UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q9UJV3 (Uniprot)	TRIM1_HUMAN	MID2	Probable E3 ubiquitin-protein ligase MID2	human	No

Protein Function

Uniprot: May play a role in microtubule stabilization.

MoonDB Dissimilar Functions

Showing 1 to 1 of 1 entries

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0009056	catabolic process	359	GO:0009059	macromolecule biosynthetic process	401, 593	6.37e-04	1.88e-40

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MoonDB Network Modules

Biological Processes

Showing 1 to 10 of 51 entries

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Module ID (MoonGO)	GO ID (BP)	GO Name
63	GO:0010467	gene expression
63	GO:0090304	nucleic acid metabolic process
63	GO:0060255	regulation of macromolecule metabolic process
67	GO:0060255	regulation of macromolecule metabolic process
73	GO:0006355	regulation of transcription, DNA-templated
127	GO:0016070	RNA metabolic process
127	GO:0010467	gene expression
132	GO:0090304	nucleic acid metabolic process
132	GO:0060255	regulation of macromolecule metabolic process
151	GO:0060255	regulation of macromolecule metabolic process

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Cellular Components

Showing 1 to 10 of 35 entries

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Module ID (MoonGO)	GO ID (CC)	GO Name
63	GO:0005634	nucleus
67	GO:0005634	nucleus
73	GO:0005634	nucleus
82	GO:0005634	nucleus
84	GO:0005634	nucleus
89	GO:0005634	nucleus
127	GO:0005634	nucleus
132	GO:0005634	nucleus
151	GO:0005634	nucleus
231	GO:0005634	nucleus

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Protein GO Annotations

Biological Processes

Showing 1 to 10 of 10 entries

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0010508	positive regulation of autophagy	IMP
GO:0016567	protein ubiquitination	IEA
GO:0032897	negative regulation of viral transcription	IDA
GO:0035372	protein localization to microtubule	IMP
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IDA
GO:0045087	innate immune response	IDA
GO:0046597	negative regulation of viral entry into host cell	IDA
GO:0051091	positive regulation of DNA binding transcription factor activity	IMP
GO:0051092	positive regulation of NF-kappaB transcription factor activity	IMP
GO:1902187	negative regulation of viral release from host cell	IDA

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Cellular Components

Showing 1 to 3 of 3 entries

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005737	cytoplasm	IEA
GO:0005874	microtubule	IDA
GO:0070062	extracellular exosome	IDA

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 234 entries

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Interactor	Also a MoonDB EMF protein
A0A024R857_HUMAN	No
A8KA13_HUMAN	No
ADT3_HUMAN	No
AEN_HUMAN	No
AL3B1_HUMAN	No
AP1M1_HUMAN	No
AQP1_HUMAN	No
ARHG5_HUMAN	No
ATL4_HUMAN	No
ATRIP_HUMAN	No

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Publications Associated

Showing 1 to 6 of 6 entries

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PMID	Article Title
10400986	MID2, a homologue of the Opitz syndrome gene MID1: similarities in a sub-cellular localization and differences in expression during development.
10644436	FXY2/MID2, a gene related to the X-linked Opitz syndrome gene FXY/MID1, maps to Xq22 and encodes a FNIII domain-containing protein that associates with microtubules.
11806752	MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, Alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15772651	The DNA sequence of the human X chromosome.
24115387	Targeted deep resequencing identifies MID2 mutation for X-linked intellectual disability with varied disease severity in a large kindred from India.

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OMIM Diseases Associated

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OMIM ID	Disease Name
300928	Mental retardation, X-linked 101

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Protein Domains Associated

Showing 1 to 10 of 36 entries

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Domain Name	Domain ID	Source
B30.2/SPRY	IPR001870	InterPro
B302_SPRY	PS50188	PROSITE
BBC	SM00502	SMART
BBOX	SM00336	SMART
BBOX	cd00021	CDD
Bbox_C	IPR003649	InterPro
BUTYPHLNCDUF	PR01407	PRINTS
Butyrophylin_SPRY	IPR003879	InterPro
ConA-like_dom_sf	IPR013320	InterPro
COS	PS51262	PROSITE

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