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A Database of Extreme Multifunctional and Moonlighting Proteins
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Protein: Q6ZU80
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
Q6ZU80 (Uniprot)
CE128_HUMAN
CEP128
Centrosomal protein of 128 kDa
human
No
Protein Function
No associated function.
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0043170
macromolecule metabolic process
20
GO:0033036
macromolecule localization
748
2.48e-08
1.95e-27
GO:0043170
macromolecule metabolic process
20
GO:0051641
cellular localization
872
4.90e-06
1.31e-91
GO:0000377
RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
294
GO:0019538
protein metabolic process
404
1.88e-02
4.66e-37
GO:0044260
cellular macromolecule metabolic process
526
GO:0033036
macromolecule localization
748
4.56e-06
3.25e-28
GO:0044260
cellular macromolecule metabolic process
526
GO:0051641
cellular localization
872
4.50e-03
3.02e-89
GO:0009059
macromolecule biosynthetic process
672
,
682
,
797
GO:0033036
macromolecule localization
748
2.32e-08
6.09e-30
GO:0009059
macromolecule biosynthetic process
672
,
682
,
797
GO:0051641
cellular localization
872
1.95e-13
6.68e-127
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
3
GO:0022607
cellular component assembly
3
GO:0060255
regulation of macromolecule metabolic process
20
GO:0019538
protein metabolic process
20
GO:0007165
signal transduction
36
GO:0022607
cellular component assembly
223
GO:0022607
cellular component assembly
223
GO:0007165
signal transduction
287
GO:0006464
cellular protein modification process
287
GO:0006355
regulation of transcription, DNA-templated
294
GO:0000398
mRNA splicing, via spliceosome
404
GO:0044267
cellular protein metabolic process
404
GO:0007165
signal transduction
419
GO:0022607
cellular component assembly
420
GO:0006464
cellular protein modification process
459
GO:0007165
signal transduction
513
GO:0007165
signal transduction
526
GO:0016070
RNA metabolic process
526
GO:0034645
cellular macromolecule biosynthetic process
526
GO:0033554
cellular response to stress
526
GO:0034654
nucleobase-containing compound biosynthetic process
526
GO:0031325
positive regulation of cellular metabolic process
526
GO:0010604
positive regulation of macromolecule metabolic process
526
GO:0051173
positive regulation of nitrogen compound metabolic process
526
GO:0006468
protein phosphorylation
526
GO:0010468
regulation of gene expression
526
GO:0031399
regulation of protein modification process
526
GO:0009966
regulation of signal transduction
629
GO:0007165
signal transduction
672
GO:0034645
cellular macromolecule biosynthetic process
672
GO:0006139
nucleobase-containing compound metabolic process
672
GO:1901362
organic cyclic compound biosynthetic process
672
GO:0009889
regulation of biosynthetic process
672
GO:0010468
regulation of gene expression
677
GO:0022607
cellular component assembly
682
GO:0034645
cellular macromolecule biosynthetic process
682
GO:0006464
cellular protein modification process
682
GO:0035556
intracellular signal transduction
682
GO:0090304
nucleic acid metabolic process
682
GO:0010468
regulation of gene expression
682
GO:0019219
regulation of nucleobase-containing compound metabolic process
684
GO:0022402
cell cycle process
684
GO:0051640
organelle localization
686
GO:0060271
cilium assembly
748
GO:0008104
protein localization
764
GO:0022607
cellular component assembly
797
GO:0034645
cellular macromolecule biosynthetic process
797
GO:0060255
regulation of macromolecule metabolic process
872
GO:0051649
establishment of localization in cell
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
3
GO:0044430
cytoskeletal part
3
GO:0005829
cytosol
3
GO:0005634
nucleus
20
GO:0005886
plasma membrane
36
GO:0005829
cytosol
36
GO:0005815
microtubule organizing center
104
GO:0005829
cytosol
104
GO:0005815
microtubule organizing center
179
GO:0012505
endomembrane system
190
GO:0005829
cytosol
190
GO:0043232
intracellular non-membrane-bounded organelle
223
GO:0005634
nucleus
226
GO:0005634
nucleus
256
GO:0043232
intracellular non-membrane-bounded organelle
256
GO:0005634
nucleus
287
GO:0005829
cytosol
287
GO:0043232
intracellular non-membrane-bounded organelle
287
GO:0031981
nuclear lumen
294
GO:0030529
intracellular ribonucleoprotein complex
294
GO:0005654
nucleoplasm
298
GO:0015630
microtubule cytoskeleton
404
GO:0005829
cytosol
404
GO:0012505
endomembrane system
404
GO:0031982
vesicle
411
GO:0005634
nucleus
417
GO:0005829
cytosol
417
GO:0043232
intracellular non-membrane-bounded organelle
419
GO:0044430
cytoskeletal part
419
GO:0005829
cytosol
420
GO:0005829
cytosol
420
GO:0005634
nucleus
459
GO:0005829
cytosol
459
GO:0043232
intracellular non-membrane-bounded organelle
459
GO:0005634
nucleus
488
GO:0005634
nucleus
488
GO:0031982
vesicle
495
GO:0043232
intracellular non-membrane-bounded organelle
495
GO:0005634
nucleus
513
GO:0005829
cytosol
513
GO:0005634
nucleus
524
GO:0005856
cytoskeleton
524
GO:0005829
cytosol
524
GO:0120025
plasma membrane bounded cell projection
526
GO:0005829
cytosol
526
GO:0031981
nuclear lumen
556
GO:0005829
cytosol
556
GO:0031982
vesicle
561
GO:0043232
intracellular non-membrane-bounded organelle
600
GO:0005634
nucleus
629
GO:0005829
cytosol
629
GO:0031982
vesicle
631
GO:0044430
cytoskeletal part
631
GO:0005829
cytosol
631
GO:0015630
microtubule cytoskeleton
639
GO:0005634
nucleus
672
GO:0031981
nuclear lumen
677
GO:0005813
centrosome
677
GO:0005829
cytosol
677
GO:0005634
nucleus
678
GO:0043232
intracellular non-membrane-bounded organelle
682
GO:0005634
nucleus
684
GO:0005829
cytosol
684
GO:0005815
microtubule organizing center
686
GO:0005813
centrosome
686
GO:0044441
ciliary part
686
GO:0005829
cytosol
686
GO:0044450
microtubule organizing center part
748
GO:0005815
microtubule organizing center
748
GO:0005634
nucleus
764
GO:0044430
cytoskeletal part
797
GO:0043232
intracellular non-membrane-bounded organelle
797
GO:0005634
nucleus
830
GO:0005856
cytoskeleton
830
GO:0005829
cytosol
830
GO:0070013
intracellular organelle lumen
830
GO:0005634
nucleus
856
GO:0005634
nucleus
872
GO:0005829
cytosol
875
GO:0005856
cytoskeleton
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0008104
protein localization
IMP
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0000922
spindle pole
IDA
GO:0005814
centriole
IDA
GO:0120103
centriolar subdistal appendage
IDA
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
ASPP2_HUMAN
No
CP135_HUMAN
Yes:
Q66GS9 (MoonDB)
HAUS1_HUMAN
No
CC138_HUMAN
No
TRIP6_HUMAN
No
TXLNA_HUMAN
No
PCBP3_HUMAN
No
DYL1_HUMAN
No
NDK7_HUMAN
No
APC_HUMAN
No
FBF1_HUMAN
No
FTM_HUMAN
No
DTNB_HUMAN
No
CC112_HUMAN
No
ARPC3_HUMAN
No
CCD66_HUMAN
No
PCM1_HUMAN
Yes:
Q15154 (MoonDB)
ODFP2_HUMAN
No
CE162_HUMAN
No
1433F_HUMAN
No
4ET_HUMAN
No
ABLM1_HUMAN
No
ADIP_HUMAN
Yes:
Q9Y2D8 (MoonDB)
ALMS1_HUMAN
No
AMOT_HUMAN
No
ANR26_HUMAN
No
ANR28_HUMAN
No
ANXA1_HUMAN
No
AP2A1_HUMAN
No
AP2B1_HUMAN
No
AP2S1_HUMAN
No
ARFG3_HUMAN
No
ARP2_HUMAN
No
ASCC2_HUMAN
No
ASCC3_HUMAN
No
ASPP1_HUMAN
No
ATX10_HUMAN
No
AURKA_HUMAN
No
BCAS3_HUMAN
No
BCR_HUMAN
No
BICD1_HUMAN
No
BICD2_HUMAN
No
BMI1_HUMAN
No
C102A_HUMAN
No
C170B_HUMAN
No
C2CD3_HUMAN
No
C2D1A_HUMAN
No
CA198_HUMAN
No
CAMP1_HUMAN
No
CAMP2_HUMAN
No
CAMP3_HUMAN
No
CBL_HUMAN
No
CBPC1_HUMAN
No
CC85C_HUMAN
No
CCD14_HUMAN
No
CCD18_HUMAN
No
CCD22_HUMAN
No
CCD77_HUMAN
No
CCNB1_HUMAN
No
CCNB2_HUMAN
No
CCSE2_HUMAN
No
CD123_HUMAN
No
CDC20_HUMAN
No
CDK5_HUMAN
No
CE120_HUMAN
Yes:
Q8N960 (MoonDB)
CE152_HUMAN
No
CE164_HUMAN
No
CE170_HUMAN
No
CE192_HUMAN
No
CE290_HUMAN
No
CE350_HUMAN
No
CE85L_HUMAN
No
CEP44_HUMAN
No
CEP55_HUMAN
No
CEP63_HUMAN
No
CEP72_HUMAN
No
CEP85_HUMAN
No
CEP89_HUMAN
No
CEP95_HUMAN
No
CEP97_HUMAN
No
CFA97_HUMAN
No
CIP2A_HUMAN
No
CKAP5_HUMAN
No
CMC1_HUMAN
No
CNTRB_HUMAN
No
CNTRL_HUMAN
No
COPA_HUMAN
No
CP110_HUMAN
No
CP131_HUMAN
No
CPVL_HUMAN
No
CRK_HUMAN
Yes:
P46108 (MoonDB)
CSKP_HUMAN
No
CSPP1_HUMAN
No
CTNB1_HUMAN
No
CTNL1_HUMAN
No
CYLD_HUMAN
No
DAPK3_HUMAN
No
DCLK1_HUMAN
No
DDX47_HUMAN
No
DESP_HUMAN
No
DHE3_HUMAN
No
DHX35_HUMAN
No
DLG5_HUMAN
No
DVL1_HUMAN
No
DVL2_HUMAN
No
DVL3_HUMAN
Yes:
Q92997 (MoonDB)
ECD_HUMAN
No
ECH1_HUMAN
No
ERLN2_HUMAN
No
EXOC4_HUMAN
No
F199X_HUMAN
No
FA83B_HUMAN
No
FERM2_HUMAN
No
FOPNL_HUMAN
No
FR1OP_HUMAN
No
GBB1_HUMAN
No
GGYF1_HUMAN
No
GID8_HUMAN
No
GPTC1_HUMAN
No
GPX1_HUMAN
No
HAUS2_HUMAN
No
HAUS3_HUMAN
No
HAUS4_HUMAN
No
HAUS5_HUMAN
No
HAUS6_HUMAN
No
HAUS7_HUMAN
No
HAUS8_HUMAN
No
HTSF1_HUMAN
No
IBTK_HUMAN
No
IFT22_HUMAN
No
IFT46_HUMAN
No
IFT57_HUMAN
No
IFT74_HUMAN
No
IFT81_HUMAN
No
IPO11_HUMAN
No
IPO8_HUMAN
No
IQCB1_HUMAN
No
K1671_HUMAN
No
KAPCA_HUMAN
No
KBTB6_HUMAN
No
KC1A_HUMAN
No
KC1D_HUMAN
No
KC1E_HUMAN
No
KIF14_HUMAN
No
KIF7_HUMAN
No
KIZ_HUMAN
No
LATS2_HUMAN
No
LIS1_HUMAN
No
LMO7_HUMAN
No
LRC47_HUMAN
No
LRC49_HUMAN
No
LTV1_HUMAN
No
LUZP1_HUMAN
No
LZTS2_HUMAN
No
LZTS3_HUMAN
No
M21D2_HUMAN
No
MA7D3_HUMAN
No
MED4_HUMAN
No
MIB1_HUMAN
No
MIB2_HUMAN
No
MIEAP_HUMAN
No
MOONR_HUMAN
No
MPP5_HUMAN
No
MPP9_HUMAN
No
NAV1_HUMAN
No
NCK5L_HUMAN
No
NCKP1_HUMAN
No
NDE1_HUMAN
No
NDEL1_HUMAN
Yes:
Q9GZM8 (MoonDB)
NDUA5_HUMAN
No
NDUS8_HUMAN
No
NEBL_HUMAN
No
NECP2_HUMAN
No
NEDD1_HUMAN
No
NFAC3_HUMAN
No
NGAP_HUMAN
No
NINL_HUMAN
No
NIN_HUMAN
No
NPHP1_HUMAN
No
NPHP4_HUMAN
No
NPL4_HUMAN
No
NRBF2_HUMAN
No
NU205_HUMAN
No
OCRL_HUMAN
No
ODB2_HUMAN
No
ODF2L_HUMAN
No
OFD1_HUMAN
No
P20D2_HUMAN
No
P2R3C_HUMAN
No
P53_HUMAN
Yes:
P04637 (MoonDB)
PALLD_HUMAN
No
PAWR_HUMAN
No
PDLI5_HUMAN
No
PDLI7_HUMAN
No
PDZ11_HUMAN
No
PEF1_HUMAN
No
PHLB2_HUMAN
No
PHLP_HUMAN
No
PHOCN_HUMAN
No
PIBF1_HUMAN
No
PKHG1_HUMAN
No
PKN2_HUMAN
No
PLAK_HUMAN
No
PLK1_HUMAN
Yes:
P53350 (MoonDB)
POC5_HUMAN
No
PRSR3_HUMAN
No
PUR8_HUMAN
No
RAD50_HUMAN
No
RB6I2_HUMAN
No
RHG21_HUMAN
No
RHG29_HUMAN
No
RPB1_HUMAN
No
SAHH2_HUMAN
No
SC24B_HUMAN
No
SCLT1_HUMAN
No
SDCG3_HUMAN
No
SDHA_HUMAN
No
SHLB1_HUMAN
No
SI1L1_HUMAN
No
SI1L2_HUMAN
No
SLAI2_HUMAN
No
SMG7_HUMAN
No
SPA24_HUMAN
No
SPA2L_HUMAN
No
SPAT2_HUMAN
No
SPICE_HUMAN
Yes:
Q8N0Z3 (MoonDB)
SRBS1_HUMAN
No
SRP72_HUMAN
No
SRSF2_HUMAN
No
STK3_HUMAN
No
STXB4_HUMAN
No
SYNC_HUMAN
No
TANC1_HUMAN
No
TANK_HUMAN
No
TBC31_HUMAN
No
TBK1_HUMAN
No
TCHP_HUMAN
No
TEX9_HUMAN
No
TMED2_HUMAN
No
TNR6B_HUMAN
No
TPGS1_HUMAN
No
TRI26_HUMAN
No
TRI37_HUMAN
No
TRI41_HUMAN
Yes:
Q8WV44 (MoonDB)
TRI56_HUMAN
No
TRIM9_HUMAN
No
TSNAX_HUMAN
No
TTF2_HUMAN
No
TTK_HUMAN
No
TTLL5_HUMAN
No
TXLNG_HUMAN
No
UBP54_HUMAN
No
UN45A_HUMAN
No
VPS45_HUMAN
No
WAC2A_HUMAN
No
WAC2C_HUMAN
No
WASC3_HUMAN
No
WASC4_HUMAN
No
WASC5_HUMAN
No
WASH1_HUMAN
No
WDR83_HUMAN
No
WRP73_HUMAN
No
XRN1_HUMAN
Yes:
Q8IZH2 (MoonDB)
YTHD1_HUMAN
No
ZDBF2_HUMAN
No
ZN622_HUMAN
No
ZO1_HUMAN
No
ZO2_HUMAN
No
ZSWM8_HUMAN
No
Publications Associated
PMID
Article Title
12508121
The DNA sequence and analysis of human chromosome 14.
14702039
Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
21399614
Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.
23186163
Toward a comprehensive characterization of a human cancer cell phosphoproteome.
24275569
An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
OMIM Diseases Associated
No results found.
Protein Domains Associated
No results found.