Protein: Q8IZH2

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
Q8IZH2 (Uniprot) XRN1_HUMAN XRN1 5'-3' exoribonuclease 1 human No
Uniprot: Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replica more..
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