Protein: Q8N960 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q8N960 (Uniprot)	CE120_HUMAN	CEP120	Centrosomal protein of 120 kDa	human	No

Protein Function

Uniprot: Plays a role in the microtubule-dependent coupling of the nucleus and the centrosome. Involved in the processes that regulate centrosome-mediated interkinetic nuclear migration (INM) of neural progenitors and for proper positioning of neurons during brain development. Also implicated in the migration and selfrene more..

MoonDB Dissimilar Functions

Showing 1 to 1 of 1 entries

Search:

GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0006725	cellular aromatic compound metabolic process	57	GO:0033036	macromolecule localization	748	1.29e-20	6.46e-74

Previous1Next

MoonDB Network Modules

Biological Processes

Showing 1 to 9 of 9 entries

Search:

Module ID (MoonGO)	GO ID (BP)	GO Name
3	GO:0022607	cellular component assembly
3	GO:0060255	regulation of macromolecule metabolic process
36	GO:0022607	cellular component assembly
57	GO:0006139	nucleobase-containing compound metabolic process
377	GO:0007165	signal transduction
419	GO:0022607	cellular component assembly
459	GO:0007165	signal transduction
469	GO:0060255	regulation of macromolecule metabolic process
748	GO:0008104	protein localization

Previous1Next

Cellular Components

Showing 1 to 10 of 23 entries

Search:

Module ID (MoonGO)	GO ID (CC)	GO Name
3	GO:0044430	cytoskeletal part
3	GO:0005829	cytosol
3	GO:0005634	nucleus
36	GO:0005829	cytosol
36	GO:0005815	microtubule organizing center
57	GO:0005634	nucleus
190	GO:0005829	cytosol
190	GO:0043232	intracellular non-membrane-bounded organelle
256	GO:0043232	intracellular non-membrane-bounded organelle
256	GO:0005634	nucleus

Previous1 2 3Next

Protein GO Annotations

Biological Processes

Showing 1 to 8 of 8 entries

Search:

GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0007098	centrosome cycle	ISS
GO:0010825	positive regulation of centrosome duplication	ISS
GO:0021987	cerebral cortex development	IEA
GO:0022008	neurogenesis	IEA
GO:0022027	interkinetic nuclear migration	IEA
GO:0030953	astral microtubule organization	IEA
GO:0032880	regulation of protein localization	IEA
GO:0045724	positive regulation of cilium assembly	ISS

Previous1Next

Cellular Components

Showing 1 to 2 of 2 entries

Search:

GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005813	centrosome	IDA
GO:0005814	centriole	ISS

Previous1Next

Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 87 entries

Search:

Interactor	Also a MoonDB EMF protein
ADIP_HUMAN	Yes: Q9Y2D8 (MoonDB)
ALMS1_HUMAN	No
ANK2_HUMAN	No
APC1_HUMAN	No
ASPP2_HUMAN	No
BTF3_HUMAN	No
CAMP1_HUMAN	No
CC138_HUMAN	No
CCD66_HUMAN	No
CCD77_HUMAN	No

Previous1 2 3 4 5…9Next

Publications Associated

Showing 1 to 8 of 8 entries

Search:

PMID	Article Title
14702039	Complete sequencing and characterization of 21,243 full-length human cDNAs.
15372022	The DNA sequence and comparative analysis of human chromosome 5.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
17974005	The full-ORF clone resource of the German cDNA consortium.
23186163	Toward a comprehensive characterization of a human cancer cell phosphoproteome.
24275569	An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
25361962	A founder CEP120 mutation in Jeune asphyxiating thoracic dystrophy expands the role of centriolar proteins in skeletal ciliopathies.
27208211	Mutations in CEP120 cause Joubert syndrome as well as complex ciliopathy phenotypes.

Previous1Next

OMIM Diseases Associated

Showing 1 to 1 of 1 entries

Search:

OMIM ID	Disease Name
616300	Short-rib thoracic dysplasia 13 with or without polydactyly

Previous1Next

Protein Domains Associated

Showing 1 to 6 of 6 entries

Search:

Domain Name	Domain ID	Source
C2	PF00168	Pfam
C2_dom	IPR000008	InterPro
C2_domain_sf	IPR035892	InterPro
DUF3668	IPR022136	InterPro
DUF3668	PF12416	Pfam
SSF49562	SSF49562	SUPFAM

Previous1Next