Protein: P53350

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P53350 (Uniprot) PLK1_HUMAN PLK1 Serine/threonine-protein kinase PLK1 human Yes
Uniprot: Serine/threonine-protein kinase that performs several important functions throughout M phase of the cell cycle, including the regulation of centrosome maturation and spindle assembly, the removal of cohesins from chromosome arms, the inactivation of anaphase-promoting complex/cyclosome (APC/C) inhibitors, and the more..

Function 1: Serine/threonine-protein kinase. Maintainance of genome stability (mitosis, DNA damage, Golgi checkpoint pathway). Condition: nuclear localisation.

Function 2: Regulates cell surbate beta1 integrin levels, involved in invasion through extracellular matrix. Condition: extracellular localisation.

Publications (PMID): 18056432

No pairs of PrOnto dissimilar CC GO terms found.
No results found.