Protein: Q9Y2D8 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q9Y2D8 (Uniprot)	ADIP_HUMAN	SSX2IP	Afadin- and alpha-actinin-binding protein	human	No

Protein Function

Uniprot: Belongs to an adhesion system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). May connect the nectin-afadin and E-cadherin-catenin system through alpha-actinin and may be involved in organization of the actin cytoskeleton at AJs through afadi more..

MoonDB Dissimilar Functions

Showing 1 to 2 of 2 entries

Search:

GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile	294	GO:0019538	protein metabolic process	665	1.88e-02	4.66e-37
GO:0044260	cellular macromolecule metabolic process	24	GO:0033036	macromolecule localization	748	4.56e-06	3.25e-28

Previous1Next

MoonDB Network Modules

Biological Processes

Showing 1 to 10 of 25 entries

Search:

Module ID (MoonGO)	GO ID (BP)	GO Name
3	GO:0022607	cellular component assembly
3	GO:0060255	regulation of macromolecule metabolic process
24	GO:0016070	RNA metabolic process
24	GO:0006464	cellular protein modification process
24	GO:0034654	nucleobase-containing compound biosynthetic process
24	GO:0006796	phosphate-containing compound metabolic process
24	GO:0031325	positive regulation of cellular metabolic process
24	GO:0010604	positive regulation of macromolecule metabolic process
24	GO:0051173	positive regulation of nitrogen compound metabolic process
24	GO:2000112	regulation of cellular macromolecule biosynthetic process

Previous1 2 3Next

Cellular Components

Showing 1 to 10 of 37 entries

Search:

Module ID (MoonGO)	GO ID (CC)	GO Name
3	GO:0044430	cytoskeletal part
3	GO:0005829	cytosol
3	GO:0005634	nucleus
24	GO:0005829	cytosol
24	GO:0005654	nucleoplasm
36	GO:0005829	cytosol
36	GO:0005815	microtubule organizing center
84	GO:0005634	nucleus
131	GO:0005829	cytosol
131	GO:0043232	intracellular non-membrane-bounded organelle

Previous1 2 3 4Next

Protein GO Annotations

Biological Processes

Showing 1 to 6 of 6 entries

Search:

GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0007098	centrosome cycle	IMP
GO:0007155	cell adhesion	IEA
GO:0035020	regulation of Rac protein signal transduction	IEA
GO:0035735	intraciliary transport involved in cilium assembly	IMP
GO:0060271	cilium assembly	IMP
GO:2000145	regulation of cell motility	IEA

Previous1Next

Cellular Components

Showing 1 to 6 of 6 entries

Search:

GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005634	nucleus	IEA
GO:0005913	cell-cell adherens junction	IEA
GO:0031252	cell leading edge	IEA
GO:0034451	centriolar satellite	IDA
GO:0036064	ciliary basal body	IDA
GO:0043234	protein complex	IDA

Previous1Next

Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 201 entries

Search:

Interactor	Also a MoonDB EMF protein
1433T_HUMAN	No
1433Z_HUMAN	Yes: P63104 (MoonDB)
4ET_HUMAN	No
AAPK1_HUMAN	No
ABLM1_HUMAN	No
ABLM3_HUMAN	No
AEN_HUMAN	No
AFAD_HUMAN	No
AHI1_HUMAN	No
AKTIP_HUMAN	No

Previous1 2 3 4 5…21Next

Publications Associated

Showing 1 to 10 of 16 entries

Search:

PMID	Article Title
10231032	Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
12007189	The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP.
14702039	Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
16710414	The DNA sequence and biological annotation of human chromosome 1.
17686061	The leukaemia-associated antigen, SSX2IP, is expressed during mitosis on the surface of myeloid leukaemia cells.
17974005	The full-ORF clone resource of the German cDNA consortium.
18669648	A quantitative atlas of mitotic phosphorylation.
19179477	Elevated expression of the leukemia-associated antigen SSX2IP predicts survival in acute myeloid leukemia patients who lack detectable cytogenetic rearrangements.
19690332	Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

Previous1 2Next

OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 3 of 3 entries

Search:

Domain Name	Domain ID	Source
ADIP	PF11559	Pfam
Afadin/alpha-actinin-bd	IPR021622	InterPro
T42649	T42649	PIR

Previous1Next