Protein: Q9BZR9 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q9BZR9 (Uniprot)	TRIM8_HUMAN	TRIM8	Probable E3 ubiquitin-protein ligase TRIM8	human	No

Protein Function

Uniprot: Probable E3 ubiquitin-protein ligase which may promote proteasomal degradation of SOCS1.

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0009056	catabolic process	125	GO:0009059	macromolecule biosynthetic process	5, 384	6.37e-04	1.88e-40

MoonDB Network Modules

Biological Processes

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Module ID (MoonGO)	GO ID (BP)	GO Name
5	GO:0034645	cellular macromolecule biosynthetic process
5	GO:0006464	cellular protein modification process
5	GO:0090304	nucleic acid metabolic process
5	GO:0034654	nucleobase-containing compound biosynthetic process
5	GO:0060255	regulation of macromolecule metabolic process
53	GO:0006139	nucleobase-containing compound metabolic process
53	GO:0016567	protein ubiquitination
53	GO:0060255	regulation of macromolecule metabolic process
79	GO:0007165	signal transduction
125	GO:0044248	cellular catabolic process

Cellular Components

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Module ID (MoonGO)	GO ID (CC)	GO Name
5	GO:0005829	cytosol
5	GO:0005634	nucleus
53	GO:0005829	cytosol
53	GO:0005654	nucleoplasm
79	GO:0005634	nucleus
125	GO:0005829	cytosol
125	GO:0005634	nucleus
131	GO:0005829	cytosol
131	GO:0043232	intracellular non-membrane-bounded organelle
131	GO:0005634	nucleus

Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0010508	positive regulation of autophagy	IMP
GO:0016567	protein ubiquitination	IEA
GO:0019827	stem cell population maintenance	IEA
GO:0032897	negative regulation of viral transcription	IEA
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	IDA
GO:0045087	innate immune response	IDA
GO:0046597	negative regulation of viral entry into host cell	IEA
GO:0051091	positive regulation of DNA binding transcription factor activity	IDA
GO:0051092	positive regulation of NF-kappaB transcription factor activity	IDA
GO:0060333	interferon-gamma-mediated signaling pathway	TAS

Cellular Components

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005829	cytosol	TAS
GO:0016605	PML body	IDA

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

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Publications Associated

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PMID	Article Title
11118312	A novel RING finger-B box-coiled-coil protein, GERP.
11331580	The tripartite motif family identifies cell compartments.
15164054	The DNA sequence and comparative analysis of human chromosome 10.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

OMIM Diseases Associated

No results found.

Protein Domains Associated

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