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A Database of Extreme Multifunctional and Moonlighting Proteins
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Protein: P43364
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
P43364 (Uniprot)
MAGAB_HUMAN
MAGEA11
Melanoma-associated antigen 11
human
No
Protein Function
Uniprot:
Acts as androgen receptor coregulator that increases androgen receptor activity by modulating the receptors interdomain interaction. May play a role in embryonal development and tumor transformation or aspects of tumor progression.
MoonDB Dissimilar Functions
Showing 1 to 3 of 3 entries
Search:
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0006139
nucleobase-containing compound metabolic process
497
,
616
GO:0051641
cellular localization
872
4.17e-16
1.54e-157
GO:0006725
cellular aromatic compound metabolic process
103
GO:0051641
cellular localization
872
2.74e-17
6.15e-158
GO:0009059
macromolecule biosynthetic process
662
GO:0051641
cellular localization
872
1.95e-13
6.68e-127
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MoonDB Network Modules
Biological Processes
Showing 1 to 10 of 19 entries
Search:
Module ID
(MoonGO)
GO ID (BP)
GO Name
99
GO:0031325
positive regulation of cellular metabolic process
99
GO:0010628
positive regulation of gene expression
99
GO:0051173
positive regulation of nitrogen compound metabolic process
99
GO:0019538
protein metabolic process
99
GO:0006357
regulation of transcription from RNA polymerase II promoter
99
GO:0007165
signal transduction
103
GO:0006139
nucleobase-containing compound metabolic process
497
GO:0090304
nucleic acid metabolic process
497
GO:0060255
regulation of macromolecule metabolic process
547
GO:0060255
regulation of macromolecule metabolic process
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Cellular Components
Showing 1 to 10 of 24 entries
Search:
Module ID
(MoonGO)
GO ID (CC)
GO Name
82
GO:0005634
nucleus
99
GO:0005654
nucleoplasm
103
GO:0070013
intracellular organelle lumen
103
GO:0005634
nucleus
224
GO:0070013
intracellular organelle lumen
224
GO:0005634
nucleus
231
GO:0005634
nucleus
497
GO:0005634
nucleus
538
GO:0043232
intracellular non-membrane-bounded organelle
547
GO:0005654
nucleoplasm
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Protein GO Annotations
Biological Processes
No results found.
Cellular Components
Showing 1 to 3 of 3 entries
Search:
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005654
nucleoplasm
IDA
GO:0005829
cytosol
IDA
GO:0016604
nuclear body
IDA
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Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Showing 1 to 10 of 114 entries
Search:
Interactor
Also a MoonDB EMF protein
ACMSD_HUMAN
No
ACO15_HUMAN
No
ACS2B_HUMAN
No
ACTN1_HUMAN
No
AK1C3_HUMAN
No
ANDR_HUMAN
Yes:
P10275 (MoonDB)
B2L11_HUMAN
No
BEX2_HUMAN
No
BIRC2_HUMAN
No
BRD1_HUMAN
No
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Publications Associated
Showing 1 to 4 of 4 entries
Search:
PMID
Article Title
7927540
Structure, chromosomal localization, and expression of 12 genes of the MAGE family.
14702039
Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15684378
Melanoma antigen gene protein MAGE-11 regulates androgen receptor function by modulating the interdomain interaction.
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OMIM Diseases Associated
No results found.
Protein Domains Associated
Showing 1 to 10 of 12 entries
Search:
Domain Name
Domain ID
Source
I38660
I38660
PIR
MAGE
IPR037445
InterPro
MAGE
PF01454
Pfam
MAGE
PS50838
PROSITE
MAGE
SM01373
SMART
MAGE_N
IPR021072
InterPro
MAGE_N
PF12440
Pfam
MAGE_N
SM01392
SMART
MAGEA11
IPR030099
InterPro
MHD_dom
IPR002190
InterPro
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