|Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.
|Adenoviral E1A-associated protein p300 as a functional homologue of the transcriptional co-activator CBP.
|A p300/CBP-associated factor that competes with the adenoviral oncoprotein E1A.
|An essential role for p300/CBP in the cellular response to hypoxia.
|The transcriptional coactivators p300 and CBP are histone acetyltransferases.
|Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.
|Chromatin remodelling by the glucocorticoid receptor requires the BRG1 complex.
|Exogenous expression of a dominant negative RORalpha1 vector in muscle cells impairs differentiation: RORalpha1 directly interacts with p300 and myoD.
|Functional role of p35srj, a novel p300/CBP binding protein, during transactivation by HIF-1.
|HIV-1 tat transcriptional activity is regulated by acetylation.
|The DNA sequence of human chromosome 22.
|Mutations truncating the EP300 acetylase in human cancers.
|The MSG1 non-DNA-binding transactivator binds to the p300/CBP coactivators, enhancing their functional link to the Smad transcription factors.
|A novel transcriptional repression domain mediates p21(WAF1/CIP1) induction of p300 transactivation.
|Thyroid hormone receptor-binding protein, an LXXLL motif-containing protein, functions as a general coactivator.
|MOZ is fused to p300 in an acute monocytic leukemia with t(8;22).
|Cells degrade a novel inhibitor of differentiation with E1A-like properties upon exiting the cell cycle.
|A novel Rb- and p300-binding protein inhibits transactivation by MyoD.
|Acetylation of HIV-1 Tat by CBP/P300 increases transcription of integrated HIV-1 genome and enhances binding to core histones.
|A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression.
|Regulation of human flap endonuclease-1 activity by acetylation through the transcriptional coactivator p300.
|Acetylation control of the retinoblastoma tumour-suppressor protein.
|The oncoprotein Tax binds the SRC-1-interacting domain of CBP/p300 to mediate transcriptional activation.
|Molecular cloning and characterization of PELP1, a novel human coregulator of estrogen receptor alpha.
|Regulation of transcription by AMP-activated protein kinase: phosphorylation of p300 blocks its interaction with nuclear receptors.
|Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.
|Role of Deltex-1 as a transcriptional regulator downstream of the Notch receptor.
|Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein.
|Adenovirus DNA binding protein interacts with the SNF2-related CBP activator protein (SrCap) and inhibits SrCap-mediated transcription.
|A transcriptional switch mediated by cofactor methylation.
|Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2.
|Interaction between the hematopoietic Ets transcription factor Spi-B and the coactivator CREB-binding protein associated with negative cross-talk with c-Myb.
|Scaffold/matrix attachment region elements interact with a p300-scaffold attachment factor A complex and are bound by acetylated nucleosomes.
|Structural basis for recruitment of CBP/p300 by hypoxia-inducible factor-1 alpha.
|Synergy among nuclear receptor coactivators: selective requirement for protein methyltransferase and acetyltransferase activities.
|Acetylation inactivates the transcriptional repressor BCL6.
|Identification of a promoter-specific transcriptional activation domain at the C-terminus of the Wnt effector protein T-cell factor 4.
|Synergism between p68 RNA helicase and the transcriptional coactivators CBP and p300.
|Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.
|P300 transcriptional repression is mediated by SUMO modification.
|p29ING4 and p28ING5 bind to p53 and p300, and enhance p53 activity.
|Structural basis for negative regulation of hypoxia-inducible factor-1alpha by CITED2.
|Acetylated SP3 is a transcriptional activator.
|P300/CBP acts as a coactivator to cartilage homeoprotein-1 (Cart1), paired-like homeoprotein, through acetylation of the conserved lysine residue adjacent to the homeodomain.
|SATB1 makes a complex with p300 and represses gp91(phox) promoter activity.
|Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.
|Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.
|Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix transcription factor BETA2/neuroD.
|Regulation of the p300 HAT domain via a novel activation loop.
|Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86.
|Ordered cooperative functions of PRMT1, p300, and CARM1 in transcriptional activation by p53.
|Regulation of human SRY subcellular distribution by its acetylation/deacetylation.
|Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53.
|SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1.
|Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.
|Regulation of coactivator complex assembly and function by protein arginine methylation and demethylimination.
|The coactivator p300 directly acetylates the forkhead transcription factor Foxo1 and stimulates Foxo1-induced transcription.
|Sp1 deacetylation induced by phorbol ester recruits p300 to activate 12(S)-lipoxygenase gene transcription.
|Nuclear Rho kinase, ROCK2, targets p300 acetyltransferase.
|MTA1, a transcriptional activator of breast cancer amplified sequence 3.
|HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription.
|BCL11B participates in the activation of IL2 gene expression in CD4+ T lymphocytes.
|The transcriptional activity of CITED1 is regulated by phosphorylation in a cell cycle-dependent manner.
|Kinetic and mass spectrometric analysis of p300 histone acetyltransferase domain autoacetylation.
|Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF.
|Lysine propionylation and butyrylation are novel post-translational modifications in histones.
|Critical and functional regulation of CHOP (C/EBP homologous protein) through the N-terminal portion.
|The structural basis of protein acetylation by the p300/CBP transcriptional coactivator.
|A quantitative atlas of mitotic phosphorylation.
|PEBP2-beta/CBF-beta-dependent phosphorylation of RUNX1 and p300 by HIPK2: implications for leukemogenesis.
|Acetylation of Sirt2 by p300 attenuates its deacetylase activity.
|PML activates transcription by protecting HIPK2 and p300 from SCFFbx3-mediated degradation.
|The SIRT2 deacetylase regulates autoacetylation of p300.
|Structural basis for p300 Taz2-p53 TAD1 binding and modulation by phosphorylation.
|Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
|Lysine acetylation targets protein complexes and co-regulates major cellular functions.
|SENP3 is responsible for HIF-1 transactivation under mild oxidative stress via p300 de-SUMOylation.
|Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
|Cyclin-dependent kinase-9 is a component of the p300/GATA4 complex required for phenylephrine-induced hypertrophy in cardiomyocytes.
|Regulation of unfolded protein response modulator XBP1s by acetylation and deacetylation.
|HDAC3 is negatively regulated by the nuclear protein DBC1.
|Initial characterization of the human central proteome.
|System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
|Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
|Histone recognition and large-scale structural analysis of the human bromodomain family.
|Human ALKBH4 interacts with proteins associated with transcription.
|Toward a comprehensive characterization of a human cancer cell phosphoproteome.
|Regulation of transcription through acetylation of H3K122 on the lateral surface of the histone octamer.
|A hybrid mechanism of action for BCL6 in B cells defined by formation of functionally distinct complexes at enhancers and promoters.
|Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation.
|Kruppel-like factor 15 is critical for vascular inflammation.
|Constitutive nuclear localization of an alternatively spliced sirtuin-2 isoform.
|An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
|Zinc finger protein 451 is a novel Smad corepressor in transforming growth factor-beta signaling.
|Human Kruppel-related 3 (HKR3) is a novel transcription activator of alternate reading frame (ARF) gene.
|Differential regulation of estrogen receptor alpha expression in breast cancer cells by metastasis-associated protein 1.
|Clinical and molecular characterization of Rubinstein-Taybi syndrome patients carrying distinct novel mutations of the EP300 gene.
|Structure of the p300 histone acetyltransferase bound to acetyl-coenzyme A and its analogues.
|CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis.
|Modification of ASC1 by UFM1 is crucial for ERalpha transactivation and breast cancer development.
|Two ZNF509 (ZBTB49) isoforms induce cell-cycle arrest by activating transcription of p21/CDKN1A and RB upon exposure to genotoxic stress.
|Intracellular crotonyl-CoA stimulates transcription through p300-catalyzed histone crotonylation.
|PARP9-DTX3L ubiquitin ligase targets host histone H2BJ and viral 3C protease to enhance interferon signaling and control viral infection.
|Heat shock factor 1 mediates latent HIV reactivation.
|Multisystem anomalies in severe combined immunodeficiency with mutant BCL11B.