Protein: Q9H6Y7 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q9H6Y7 (Uniprot)	RN167_HUMAN	RNF167	E3 ubiquitin-protein ligase RNF167	human	No

Protein Function

Uniprot: May act as an E3 ubiquitin-protein ligase, or as part of the E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, such as UBE2E1, and then transfers it to substrates, such as SLC22A18. May play a role in growth regulation involved in G1/S transition.

MoonDB Dissimilar Functions

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0009056	catabolic process	125	GO:0009059	macromolecule biosynthetic process	286	6.37e-04	1.88e-40

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MoonDB Network Modules

Biological Processes

Showing 1 to 8 of 8 entries

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Module ID (MoonGO)	GO ID (BP)	GO Name
125	GO:0044248	cellular catabolic process
125	GO:0016567	protein ubiquitination
125	GO:0060255	regulation of macromolecule metabolic process
286	GO:0034645	cellular macromolecule biosynthetic process
286	GO:0090304	nucleic acid metabolic process
286	GO:0034654	nucleobase-containing compound biosynthetic process
286	GO:0010468	regulation of gene expression
458	GO:0006139	nucleobase-containing compound metabolic process

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Cellular Components

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Module ID (MoonGO)	GO ID (CC)	GO Name
125	GO:0005829	cytosol
125	GO:0005634	nucleus
286	GO:0044428	nuclear part
458	GO:0005634	nucleus

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Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0000209	protein polyubiquitination	IDA
GO:0045786	negative regulation of cell cycle	IMP

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Cellular Components

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005737	cytoplasm	IDA
GO:0012505	endomembrane system	IEA
GO:0016021	integral component of membrane	IEA

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Dissimilar Cellular Components (PrOnto)

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GO ID 1	Component 1	GO ID 2	Component 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0005737	cytoplasm	GO:0016021	integral component of membrane	2.01e-156	1.16e-04

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All Protein Interactions

Showing 1 to 10 of 17 entries

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Interactor	Also a MoonDB EMF protein
ACTS_HUMAN	No
AFG32_HUMAN	No
AT2A1_HUMAN	No
CAN3_HUMAN	No
MYH7_HUMAN	No
S22AI_HUMAN	No
SUMO1_HUMAN	Yes: P63165 (MoonDB)
TITIN_HUMAN	Yes: Q8WZ42 (MoonDB)
UB2D1_HUMAN	Yes: P51668 (MoonDB)
UB2D2_HUMAN	Yes: P62837 (MoonDB)

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Publications Associated

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PMID	Article Title
14702039	Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15498874	Large-scale cDNA transfection screening for genes related to cancer development and progression.
16314844	Tumor suppressor candidate TSSC5 is regulated by UbcH6 and a novel ubiquitin ligase RING105.
17974005	The full-ORF clone resource of the German cDNA consortium.
24275569	An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 10 of 10 entries

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Domain Name	Domain ID	Source
PA	PF02225	Pfam
PA_domain	IPR003137	InterPro
RING	SM00184	SMART
RINGv	SM00744	SMART
T08729	T08729	PIR
zf-RING_2	PF13639	Pfam
ZF_RING_2	PS50089	PROSITE
Znf_RING	IPR001841	InterPro
Znf_RING-CH	IPR011016	InterPro
Znf_RING/FYVE/PHD	IPR013083	InterPro

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