Protein: Q9Y2X8 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q9Y2X8 (Uniprot)	UB2D4_HUMAN	UBE2D4	Ubiquitin-conjugating enzyme E2 D4	human	No

Protein Function

Uniprot: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro able to promote polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11' and 'Lys-48'-linked polyubiquitination.

MoonDB Dissimilar Functions

Showing 1 to 1 of 1 entries

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0009056	catabolic process	125	GO:0009059	macromolecule biosynthetic process	270	6.37e-04	1.88e-40

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MoonDB Network Modules

Biological Processes

Showing 1 to 10 of 23 entries

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Module ID (MoonGO)	GO ID (BP)	GO Name
53	GO:0006139	nucleobase-containing compound metabolic process
53	GO:0016567	protein ubiquitination
53	GO:0060255	regulation of macromolecule metabolic process
125	GO:0044248	cellular catabolic process
125	GO:0016567	protein ubiquitination
125	GO:0060255	regulation of macromolecule metabolic process
270	GO:0034645	cellular macromolecule biosynthetic process
270	GO:0010467	gene expression
270	GO:0090304	nucleic acid metabolic process
270	GO:0032446	protein modification by small protein conjugation

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Cellular Components

Showing 1 to 10 of 14 entries

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Module ID (MoonGO)	GO ID (CC)	GO Name
53	GO:0005829	cytosol
53	GO:0005654	nucleoplasm
125	GO:0005829	cytosol
125	GO:0005634	nucleus
270	GO:0005829	cytosol
270	GO:0070013	intracellular organelle lumen
270	GO:0005634	nucleus
359	GO:0005634	nucleus
375	GO:0005829	cytosol
375	GO:0005634	nucleus

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Protein GO Annotations

Biological Processes

Showing 1 to 7 of 7 entries

Search:

GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0016567	protein ubiquitination	IDA
GO:0035519	protein K29-linked ubiquitination	IDA
GO:0044314	protein K27-linked ubiquitination	IDA
GO:0070534	protein K63-linked ubiquitination	IDA
GO:0070936	protein K48-linked ubiquitination	IDA
GO:0070979	protein K11-linked ubiquitination	IDA
GO:0085020	protein K6-linked ubiquitination	IDA

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Cellular Components

No results found.

Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 103 entries

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Interactor	Also a MoonDB EMF protein
AL1A2_HUMAN	No
AMFR_HUMAN	No
ARI2_HUMAN	No
BFAR_HUMAN	No
BIRC8_HUMAN	No
CAPS2_HUMAN	No
CARM1_HUMAN	No
CHFR_HUMAN	No
CNOT4_HUMAN	No
DAZP2_HUMAN	Yes: Q15038 (MoonDB)

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Publications Associated

Showing 1 to 4 of 4 entries

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PMID	Article Title
12690205	Human chromosome 7: DNA sequence and biology.
14702039	Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
20061386	The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 8 of 8 entries

Search:

Domain Name	Domain ID	Source
SSF54495	SSF54495	SUPFAM
UBCc	cd00195	CDD
UBIQUITIN_CONJUGAT_1	PS00183	PROSITE
UBIQUITIN_CONJUGAT_2	PS50127	PROSITE
UBQ-conjugat_E2	IPR000608	InterPro
UBQ-conjugating_AS	IPR023313	InterPro
UBQ-conjugating_enzyme/RWD	IPR016135	InterPro
UQ_con	PF00179	Pfam

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