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A Database of Extreme Multifunctional and Moonlighting Proteins
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Protein: Q96D03
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
Q96D03 (Uniprot)
DDT4L_HUMAN
DDIT4L
DNA damage-inducible transcript 4-like protein
human
No
Protein Function
Uniprot:
Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.
MoonDB Dissimilar Functions
Showing 1 to 1 of 1 entries
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GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0019538
protein metabolic process
181
GO:0016070
RNA metabolic process
719
5.15e-08
2.82e-13
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MoonDB Network Modules
Biological Processes
Showing 1 to 10 of 12 entries
Search:
Module ID
(MoonGO)
GO ID (BP)
GO Name
181
GO:0044267
cellular protein metabolic process
181
GO:0010467
gene expression
181
GO:0009059
macromolecule biosynthetic process
181
GO:0090304
nucleic acid metabolic process
181
GO:0060255
regulation of macromolecule metabolic process
181
GO:0007165
signal transduction
364
GO:0016070
RNA metabolic process
364
GO:0010468
regulation of gene expression
719
GO:0006401
RNA catabolic process
719
GO:0016071
mRNA metabolic process
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Cellular Components
Showing 1 to 9 of 9 entries
Search:
Module ID
(MoonGO)
GO ID (CC)
GO Name
181
GO:0005829
cytosol
181
GO:0005654
nucleoplasm
208
GO:0005634
nucleus
364
GO:0005634
nucleus
634
GO:0005829
cytosol
634
GO:0005634
nucleus
719
GO:0005829
cytosol
719
GO:0043232
intracellular non-membrane-bounded organelle
719
GO:0005634
nucleus
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Protein GO Annotations
Biological Processes
Showing 1 to 1 of 1 entries
Search:
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0009968
negative regulation of signal transduction
IEA
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Cellular Components
Showing 1 to 1 of 1 entries
Search:
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005737
cytoplasm
ISS
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Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Showing 1 to 10 of 149 entries
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Interactor
Also a MoonDB EMF protein
4EBP1_HUMAN
No
A0A024R4Q5_HUMAN
No
AAKB2_HUMAN
No
ACBP_HUMAN
No
ACY3_HUMAN
No
AIDA_HUMAN
No
AKT1_HUMAN
No
AP4A_HUMAN
No
ARPIN_HUMAN
No
B2L14_HUMAN
No
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Publications Associated
Showing 1 to 7 of 7 entries
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PMID
Article Title
12453409
REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species.
14702039
Complete sequencing and characterization of 21,243 full-length human cDNAs.
15308555
REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.
15489334
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15545625
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex.
15632201
The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway.
17974005
The full-ORF clone resource of the German cDNA consortium.
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OMIM Diseases Associated
No results found.
Protein Domains Associated
Showing 1 to 3 of 3 entries
Search:
Domain Name
Domain ID
Source
PTHR12478
PTHR12478
PANTHER
RTP801-like
IPR012918
InterPro
RTP801_C
PF07809
Pfam
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