Protein: Q96D03 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q96D03 (Uniprot)	DDT4L_HUMAN	DDIT4L	DNA damage-inducible transcript 4-like protein	human	No

Protein Function

Uniprot: Inhibits cell growth by regulating the TOR signaling pathway upstream of the TSC1-TSC2 complex and downstream of AKT1.

MoonDB Dissimilar Functions

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0019538	protein metabolic process	181	GO:0016070	RNA metabolic process	719	5.15e-08	2.82e-13

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MoonDB Network Modules

Biological Processes

Showing 1 to 10 of 12 entries

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Module ID (MoonGO)	GO ID (BP)	GO Name
181	GO:0044267	cellular protein metabolic process
181	GO:0010467	gene expression
181	GO:0009059	macromolecule biosynthetic process
181	GO:0090304	nucleic acid metabolic process
181	GO:0060255	regulation of macromolecule metabolic process
181	GO:0007165	signal transduction
364	GO:0016070	RNA metabolic process
364	GO:0010468	regulation of gene expression
719	GO:0006401	RNA catabolic process
719	GO:0016071	mRNA metabolic process

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Cellular Components

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Module ID (MoonGO)	GO ID (CC)	GO Name
181	GO:0005829	cytosol
181	GO:0005654	nucleoplasm
208	GO:0005634	nucleus
364	GO:0005634	nucleus
634	GO:0005829	cytosol
634	GO:0005634	nucleus
719	GO:0005829	cytosol
719	GO:0043232	intracellular non-membrane-bounded organelle
719	GO:0005634	nucleus

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Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0009968	negative regulation of signal transduction	IEA

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Cellular Components

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005737	cytoplasm	ISS

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 149 entries

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Interactor	Also a MoonDB EMF protein
4EBP1_HUMAN	No
A0A024R4Q5_HUMAN	No
AAKB2_HUMAN	No
ACBP_HUMAN	No
ACY3_HUMAN	No
AIDA_HUMAN	No
AKT1_HUMAN	No
AP4A_HUMAN	No
ARPIN_HUMAN	No
B2L14_HUMAN	No

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Publications Associated

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PMID	Article Title
12453409	REDD1, a developmentally regulated transcriptional target of p63 and p53, links p63 to regulation of reactive oxygen species.
14702039	Complete sequencing and characterization of 21,243 full-length human cDNAs.
15308555	REDD2 gene is upregulated by modified LDL or hypoxia and mediates human macrophage cell death.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15545625	Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex.
15632201	The stress-inducted proteins RTP801 and RTP801L are negative regulators of the mammalian target of rapamycin pathway.
17974005	The full-ORF clone resource of the German cDNA consortium.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 3 of 3 entries

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Domain Name	Domain ID	Source
PTHR12478	PTHR12478	PANTHER
RTP801-like	IPR012918	InterPro
RTP801_C	PF07809	Pfam

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