Protein: P14618

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P14618 (Uniprot) KPYM_HUMAN PKM Pyruvate kinase PKM human Yes
Uniprot: Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio between the highly active tetrameric form and nearly in more..

Function 1: Pyruvate kinase, glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP. Condition: presence in a tetrameric form.

Function 2: Thyroid hormone-binding protein that regulates the transcriptional responses of the thiroid hormone receptor. Condition: presence in a monomeric form.

Publications (PMID): 15877277

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