Protein: Q86X19

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
Q86X19 (Uniprot) TMM17_HUMAN TMEM17 Transmembrane protein 17 human No
Uniprot: Transmembrane component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity).
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0043170 macromolecule metabolic process 531 GO:0071705 nitrogen compound transport 624 9.47e-16 1.65e-67
GO:0043170 macromolecule metabolic process 531 GO:0042886 amide transport 663 2.11e-04 2.73e-69
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
10 GO:0007165 signal transduction
41 GO:0007165 signal transduction
128 GO:0007165 signal transduction
134 GO:0044267 cellular protein metabolic process
134 GO:0060255 regulation of macromolecule metabolic process
134 GO:0007165 signal transduction
212 GO:0007165 signal transduction
217 GO:0060255 regulation of macromolecule metabolic process
217 GO:0007165 signal transduction
275 GO:0022607 cellular component assembly
275 GO:0006796 phosphate-containing compound metabolic process
275 GO:0060255 regulation of macromolecule metabolic process
275 GO:0007165 signal transduction
303 GO:0007165 signal transduction
304 GO:0044267 cellular protein metabolic process
304 GO:0007165 signal transduction
333 GO:0060255 regulation of macromolecule metabolic process
333 GO:0009966 regulation of signal transduction
409 GO:0007165 signal transduction
500 GO:0007165 signal transduction
531 GO:0019538 protein metabolic process
536 GO:0010604 positive regulation of macromolecule metabolic process
536 GO:0051173 positive regulation of nitrogen compound metabolic process
536 GO:0019538 protein metabolic process
536 GO:0007165 signal transduction
540 GO:0022607 cellular component assembly
541 GO:0007165 signal transduction
585 GO:0006139 nucleobase-containing compound metabolic process
624 GO:0042886 amide transport
624 GO:0022607 cellular component assembly
663 GO:0015833 peptide transport
663 GO:0008104 protein localization
787 GO:0016070 RNA metabolic process
787 GO:0010467 gene expression
787 GO:0060255 regulation of macromolecule metabolic process
787 GO:0007165 signal transduction
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
30 GO:0005829 cytosol
30 GO:0043232 intracellular non-membrane-bounded organelle
41 GO:0030054 cell junction
41 GO:0044459 plasma membrane part
43 GO:0005634 nucleus
85 GO:0016021 integral component of membrane
128 GO:0012505 endomembrane system
128 GO:0016021 integral component of membrane
128 GO:0005886 plasma membrane
134 GO:0005829 cytosol
134 GO:0005634 nucleus
168 GO:0012505 endomembrane system
168 GO:0016021 integral component of membrane
174 GO:0016021 integral component of membrane
179 GO:0012505 endomembrane system
213 GO:0005634 nucleus
217 GO:0005829 cytosol
217 GO:0043232 intracellular non-membrane-bounded organelle
227 GO:0005634 nucleus
275 GO:0043232 intracellular non-membrane-bounded organelle
275 GO:0005634 nucleus
315 GO:0016021 integral component of membrane
315 GO:0005886 plasma membrane
315 GO:0031982 vesicle
333 GO:0016021 integral component of membrane
333 GO:0098590 plasma membrane region
350 GO:0012505 endomembrane system
350 GO:0031224 intrinsic component of membrane
361 GO:0005829 cytosol
388 GO:0016021 integral component of membrane
389 GO:0012505 endomembrane system
389 GO:0016021 integral component of membrane
402 GO:0005829 cytosol
409 GO:0005829 cytosol
500 GO:0043232 intracellular non-membrane-bounded organelle
500 GO:0070013 intracellular organelle lumen
500 GO:0005634 nucleus
500 GO:0031982 vesicle
536 GO:0005829 cytosol
536 GO:0005634 nucleus
540 GO:0005829 cytosol
540 GO:0043232 intracellular non-membrane-bounded organelle
540 GO:0005634 nucleus
585 GO:0031981 nuclear lumen
624 GO:0031090 organelle membrane
624 GO:0044459 plasma membrane part
624 GO:0031982 vesicle
663 GO:0005829 cytosol
663 GO:0031982 vesicle
666 GO:0016021 integral component of membrane
687 GO:0031981 nuclear lumen
787 GO:0005634 nucleus
815 GO:0005794 Golgi apparatus
815 GO:0098588 bounding membrane of organelle
815 GO:0016021 integral component of membrane
815 GO:0031984 organelle subcompartment
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0007224 smoothened signaling pathway ISS
GO:0060271 cilium assembly ISS
GO:1905515 non-motile cilium assembly IMP
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0016021 integral component of membrane IEA
GO:0035869 ciliary transition zone ISS
GO:0036038 MKS complex ISS
GO:0060170 ciliary membrane ISS
No pairs of PrOnto dissimilar CC GO terms found.
Interactor Also a MoonDB EMF protein
SDCB1_HUMAN Yes: O00560 (MoonDB)
AP3M1_HUMAN No
TM237_HUMAN Yes: Q96Q45 (MoonDB)
S38A1_HUMAN No
JPH1_HUMAN No
ESYT2_HUMAN No
1433F_HUMAN No
1A03_HUMAN No
4F2_HUMAN No
AAAT_HUMAN No
ABCE1_HUMAN No
ACATN_HUMAN No
ACSL3_HUMAN No
ADCY9_HUMAN No
ADDG_HUMAN No
AGRL2_HUMAN No
AKAP5_HUMAN No
AKT2_HUMAN No
AL3A2_HUMAN No
ALG9_HUMAN No
ANK3_HUMAN No
ANKL2_HUMAN No
ANO6_HUMAN No
AP1B1_HUMAN No
AP2S1_HUMAN No
AP4B1_HUMAN No
AP4E1_HUMAN No
APBB1_HUMAN No
AR13B_HUMAN No
ARFG2_HUMAN No
ARFG3_HUMAN No
ARFP1_HUMAN No
ARFP2_HUMAN No
AT11C_HUMAN No
AT1A1_HUMAN No
AT2B1_HUMAN No
AT2B4_HUMAN No
AT2C1_HUMAN No
ATP7A_HUMAN No
AUP1_HUMAN No
B9D1_HUMAN No
BAP31_HUMAN No
BET1L_HUMAN No
BET1_HUMAN No
BI2L1_HUMAN No
BTF3_HUMAN No
CAHD1_HUMAN No
CAMLG_HUMAN No
CAV1_HUMAN No
CBARP_HUMAN No
CBPD_HUMAN No
CC115_HUMAN No
CC50A_HUMAN No
CCD47_HUMAN No
CD99_HUMAN No
CDCA3_HUMAN No
CDKAL_HUMAN No
CKAP4_HUMAN No
CLCC1_HUMAN No
CLCN7_HUMAN No
CNNM2_HUMAN No
CNNM3_HUMAN No
COG3_HUMAN No
COPA_HUMAN No
COPD_HUMAN No
COPE_HUMAN No
COPG1_HUMAN No
CP51A_HUMAN No
CPNE8_HUMAN No
CSKP_HUMAN No
CTND1_HUMAN No
CTR1_HUMAN No
CTR2_HUMAN No
CXAR_HUMAN No
CYFP1_HUMAN No
DDRGK_HUMAN No
DDX54_HUMAN No
DEP1B_HUMAN No
DHRS7_HUMAN No
DLG1_HUMAN No
DP13A_HUMAN Yes: Q9UKG1 (MoonDB)
DSC2_HUMAN No
DSG2_HUMAN No
DVL1_HUMAN No
DYST_HUMAN No
E41L1_HUMAN No
E41L5_HUMAN No
EAA1_HUMAN No
EFNB1_HUMAN No
EFNB2_HUMAN No
EFR3B_HUMAN No
EHBP1_HUMAN No
EM55_HUMAN No
EMC1_HUMAN No
EMC2_HUMAN No
EMC3_HUMAN No
EMC7_HUMAN No
EMC8_HUMAN No
EMD_HUMAN No
EPHA2_HUMAN No
EPHB4_HUMAN No
EPN1_HUMAN Yes: Q9Y6I3 (MoonDB)
EPN2_HUMAN No
EPN4_HUMAN No
EPS15_HUMAN Yes: P42566 (MoonDB)
ERBIN_HUMAN No
ERIC5_HUMAN No
ESYT1_HUMAN No
EXOC3_HUMAN No
EXOC4_HUMAN No
F1711_HUMAN No
F1712_HUMAN No
F171B_HUMAN No
F219A_HUMAN No
F234A_HUMAN No
F91A1_HUMAN No
FERM2_HUMAN No
FLOT2_HUMAN No
FLVC1_HUMAN No
FNBP1_HUMAN No
FND3A_HUMAN No
FRS2_HUMAN No
FZD5_HUMAN No
FZD6_HUMAN No
GCC1_HUMAN No
GCP60_HUMAN No
GGA1_HUMAN No
GGA3_HUMAN No
GO45_HUMAN No
GOGA5_HUMAN No
GOPC_HUMAN No
GORAB_HUMAN No
GORS2_HUMAN No
GOSR1_HUMAN No
GOSR2_HUMAN No
GP107_HUMAN No
GP108_HUMAN No
GP180_HUMAN No
GPAT3_HUMAN No
GPAT4_HUMAN No
GPHRA_HUMAN No
HGS_HUMAN No
HIP1_HUMAN Yes: O00291 (MoonDB)
HM13_HUMAN No
HMOX2_HUMAN No
HS12A_HUMAN No
ICLN_HUMAN No
INSR_HUMAN No
IRS4_HUMAN No
ISCA1_HUMAN No
ITA6_HUMAN No
ITB1_HUMAN No
ITM2B_HUMAN No
ITM2C_HUMAN No
JAG2_HUMAN No
K1549_HUMAN No
K319L_HUMAN No
KDIS_HUMAN No
KIRR1_HUMAN No
KPCI_HUMAN No
KTN1_HUMAN No
L2GL1_HUMAN No
LAT1_HUMAN No
LBR_HUMAN No
LCAP_HUMAN No
LIN7C_HUMAN No
LIPB1_HUMAN No
LMAN1_HUMAN No
LNP_HUMAN No
LRBA_HUMAN No
LRP2_HUMAN No
LRP6_HUMAN No
LRP8_HUMAN No
LSR_HUMAN No
LYN_HUMAN No
LYSM3_HUMAN No
M21D2_HUMAN No
M4K4_HUMAN No
MALD2_HUMAN No
MAN1_HUMAN No
MARK2_HUMAN No
MARK3_HUMAN No
MEP50_HUMAN No
MFAP3_HUMAN No
MKS1_HUMAN No
MMGT1_HUMAN No
MPP7_HUMAN No
MPRI_HUMAN No
MPZL1_HUMAN No
MRP1_HUMAN No
MRP5_HUMAN No
MRP_HUMAN No
MSPD2_HUMAN No
MTMR6_HUMAN No
MUC18_HUMAN No
NB5R3_HUMAN No
NBEA_HUMAN No
NCKP1_HUMAN No
NDC1_HUMAN No
NDRG1_HUMAN No
NDUS3_HUMAN No
NDUS8_HUMAN No
NECT2_HUMAN No
NETO2_HUMAN No
NGAP_HUMAN No
NIBL1_HUMAN No
NIPS2_HUMAN No
NOTC1_HUMAN No
NOTC2_HUMAN No
NSA2_HUMAN No
NSDHL_HUMAN No
NSMA3_HUMAN No
NU155_HUMAN No
NUMB_HUMAN No
OCLN_HUMAN No
OCRL_HUMAN No
OSB11_HUMAN No
OSBL8_HUMAN No
OSBP1_HUMAN No
P85A_HUMAN Yes: P27986 (MoonDB)
PACE1_HUMAN No
PACN2_HUMAN No
PAK4_HUMAN No
PALD_HUMAN No
PALM_HUMAN No
PANX1_HUMAN No
PAQR1_HUMAN No
PARD3_HUMAN No
PCDH7_HUMAN No
PDXD1_HUMAN No
PDZ11_HUMAN No
PDZD8_HUMAN No
PGRC2_HUMAN No
PHAR4_HUMAN No
PIGU_HUMAN No
PKHA1_HUMAN No
PKHA5_HUMAN No
PKP2_HUMAN No
PKP4_HUMAN No
PLAK_HUMAN No
PLD3_HUMAN No
PODXL_HUMAN No
PREB_HUMAN No
PRRT3_HUMAN No
PTK7_HUMAN No
PTN13_HUMAN No
PTN1_HUMAN No
PTN2_HUMAN No
RAB23_HUMAN No
RAB2A_HUMAN No
RAB5B_HUMAN No
RAB7A_HUMAN No
RABL3_HUMAN No
RABL6_HUMAN No
RAI14_HUMAN No
RAI3_HUMAN No
RB11B_HUMAN No
RCAS1_HUMAN No
RELL1_HUMAN No
RENR_HUMAN No
RER1_HUMAN No
RFIP5_HUMAN No
RHBD2_HUMAN No
RHBD3_HUMAN No
RHG01_HUMAN No
ROR1_HUMAN No
ROR2_HUMAN No
RPF2_HUMAN No
S12A2_HUMAN No
S12A4_HUMAN No
S12A6_HUMAN No
S12A7_HUMAN No
S19A1_HUMAN No
S20A1_HUMAN No
S20A2_HUMAN No
S23IP_HUMAN No
S29A1_HUMAN No
S35B3_HUMAN No
S35F2_HUMAN No
S38A2_HUMAN No
S39A6_HUMAN No
S39AA_HUMAN No
S39AE_HUMAN No
S4A7_HUMAN No
S6A15_HUMAN No
SAHH2_HUMAN No
SATT_HUMAN No
SC11A_HUMAN No
SC22B_HUMAN No
SC23A_HUMAN No
SC23B_HUMAN No
SC24A_HUMAN No
SC24B_HUMAN No
SC31A_HUMAN No
SC5A3_HUMAN No
SC5A6_HUMAN No
SC6A6_HUMAN No
SC6A8_HUMAN No
SC6A9_HUMAN No
SCAM1_HUMAN No
SCAM2_HUMAN No
SCAM3_HUMAN No
SCAM4_HUMAN No
SCFD1_HUMAN No
SCRB1_HUMAN No
SCRIB_HUMAN Yes: Q14160 (MoonDB)
SCYL1_HUMAN No
SCYL2_HUMAN No
SEC63_HUMAN No
SEM4C_HUMAN No
SEM6A_HUMAN No
SENP2_HUMAN No
SHSA2_HUMAN No
SL9A1_HUMAN No
SMAP2_HUMAN No
SMCR8_HUMAN No
SNP23_HUMAN No
SNP47_HUMAN No
SNX2_HUMAN No
SNX3_HUMAN No
SO4A1_HUMAN No
SO4C1_HUMAN No
SOAT1_HUMAN No
SPCS3_HUMAN No
SPY4_HUMAN No
SQSTM_HUMAN Yes: Q13501 (MoonDB)
SRPRA_HUMAN No
STAM1_HUMAN No
STAM2_HUMAN No
STEA3_HUMAN No
STIM1_HUMAN No
STIM2_HUMAN No
STOM_HUMAN No
STX10_HUMAN No
STX12_HUMAN No
STX16_HUMAN No
STX5_HUMAN No
STX6_HUMAN No
STX7_HUMAN No
STX8_HUMAN No
TB22B_HUMAN No
TBCD5_HUMAN No
TEN3_HUMAN No
TFG_HUMAN Yes: Q92734 (MoonDB)
TFR1_HUMAN No
THEM6_HUMAN No
TM115_HUMAN No
TM138_HUMAN No
TM199_HUMAN No
TM209_HUMAN No
TM87A_HUMAN No
TMEM2_HUMAN No
TMEM9_HUMAN No
TMM51_HUMAN No
TMX1_HUMAN No
TNIK_HUMAN No
TOIP1_HUMAN No
TOLIP_HUMAN No
TR10B_HUMAN No
TRI13_HUMAN No
TRIPB_HUMAN No
TRM7_HUMAN No
TV23B_HUMAN No
UB2J1_HUMAN No
UBIA1_HUMAN No
UBXN4_HUMAN No
UNC5B_HUMAN No
UNC5C_HUMAN No
US6NL_HUMAN No
USO1_HUMAN No
UTRO_HUMAN No
VAMP2_HUMAN No
VAMP3_HUMAN No
VAMP4_HUMAN No
VAMP7_HUMAN No
VAMP8_HUMAN No
VANG1_HUMAN No
VANG2_HUMAN No
VAS1_HUMAN No
VATF_HUMAN No
VEZA_HUMAN No
VKORL_HUMAN No
VMA21_HUMAN No
VPS45_HUMAN No
VPS51_HUMAN No
VRK2_HUMAN No
WASF2_HUMAN No
WDR11_HUMAN No
WDR20_HUMAN No
WDR41_HUMAN No
WDR6_HUMAN No
XCT_HUMAN No
YES_HUMAN No
YIF1A_HUMAN No
YKT6_HUMAN No
ZCCHV_HUMAN No
ZDH20_HUMAN No
ZDHC5_HUMAN No
ZNT1_HUMAN No
ZNT5_HUMAN No
ZNT6_HUMAN No
PMID Article Title
15489334 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15815621 Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
26982032 MKS5 and CEP290 dependent assembly pathway of the ciliary transition zone.
OMIM ID Disease Name
277170 Orofaciodigital syndrome 6
Domain Name Domain ID Source
Uncharacterised_TM-17 IPR019184 InterPro
Transmemb_17 PF09799 Pfam
PTHR13531 PTHR13531 PANTHER