Protein: Q5VVX9

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
Q5VVX9 (Uniprot) UBE2U_HUMAN UBE2U Ubiquitin-conjugating enzyme E2 U human No
Uniprot: Catalyzes the covalent attachment of ubiquitin to other proteins.
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0009056 catabolic process 125 GO:0009059 macromolecule biosynthetic process 270, 384 6.37e-04 1.88e-40
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
125 GO:0044248 cellular catabolic process
125 GO:0016567 protein ubiquitination
125 GO:0060255 regulation of macromolecule metabolic process
164 GO:0044267 cellular protein metabolic process
164 GO:0060255 regulation of macromolecule metabolic process
164 GO:0007165 signal transduction
270 GO:0034645 cellular macromolecule biosynthetic process
270 GO:0010467 gene expression
270 GO:0090304 nucleic acid metabolic process
270 GO:0032446 protein modification by small protein conjugation
270 GO:0060255 regulation of macromolecule metabolic process
270 GO:0007165 signal transduction
375 GO:0070647 protein modification by small protein conjugation or removal
375 GO:0060255 regulation of macromolecule metabolic process
384 GO:0034645 cellular macromolecule biosynthetic process
384 GO:0006464 cellular protein modification process
384 GO:0090304 nucleic acid metabolic process
384 GO:0031326 regulation of cellular biosynthetic process
384 GO:0060255 regulation of macromolecule metabolic process
384 GO:0007165 signal transduction
575 GO:0016567 protein ubiquitination
575 GO:0060255 regulation of macromolecule metabolic process
713 GO:0090304 nucleic acid metabolic process
713 GO:0070647 protein modification by small protein conjugation or removal
713 GO:0007165 signal transduction
807 GO:0070647 protein modification by small protein conjugation or removal
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
18 GO:0005829 cytosol
18 GO:0070062 extracellular exosome
125 GO:0005829 cytosol
125 GO:0005634 nucleus
270 GO:0005829 cytosol
270 GO:0070013 intracellular organelle lumen
270 GO:0005634 nucleus
289 GO:0005634 nucleus
375 GO:0005829 cytosol
375 GO:0005634 nucleus
384 GO:0005829 cytosol
384 GO:0031981 nuclear lumen
575 GO:0005654 nucleoplasm
697 GO:0043232 intracellular non-membrane-bounded organelle
697 GO:0005634 nucleus
713 GO:0005829 cytosol
713 GO:0005634 nucleus
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0000209 protein polyubiquitination IBA
GO:0006281 DNA repair IBA
GO:0016574 histone ubiquitination IBA
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0000790 nuclear chromatin IBA
GO:0005737 cytoplasm IBA
GO:0033503 HULC complex IBA
GO ID 1 Component 1 GO ID 2 Component 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0000790 nuclear chromatin GO:0005737 cytoplasm 4.55e-08 5.17e-23
PMID Article Title
15489334 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
16710414 The DNA sequence and biological annotation of human chromosome 1.
22496338 A human ubiquitin conjugating enzyme (E2)-HECT E3 ligase structure-function screen.
No results found.
Domain Name Domain ID Source
UBQ-conjugat_E2 IPR000608 InterPro
UBQ-conjugating_enzyme/RWD IPR016135 InterPro
UBQ-conjugating_AS IPR023313 InterPro
UQ_con PF00179 Pfam
UBIQUITIN_CONJUGAT_1 PS00183 PROSITE
UBIQUITIN_CONJUGAT_2 PS50127 PROSITE
SSF54495 SSF54495 SUPFAM
UBCc cd00195 CDD