Protein: Q12349 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q12349 (Uniprot)	ATP14_YEAST	ATP14	ATP synthase subunit H, mitochondrial	yeast	No

Protein Function

Uniprot: Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembrane more..

MoonDB Dissimilar Functions

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0006139	nucleobase-containing compound metabolic process	1059	GO:0006811	ion transport	1226	1.46e-19	8.47e-83
GO:0006725	cellular aromatic compound metabolic process	1176	GO:0006811	ion transport	1226	1.93e-19	6.20e-85
GO:0006811	ion transport	1226	GO:0034641	cellular nitrogen compound metabolic process	965	4.44e-27	1.76e-86
GO:0006811	ion transport	1226	GO:0009059	macromolecule biosynthetic process	1258	2.67e-40	7.66e-50
GO:0006811	ion transport	1226	GO:0044249	cellular biosynthetic process	1332	1.64e-27	1.21e-05
GO:0009059	macromolecule biosynthetic process	1258	GO:0015833	peptide transport	941	5.69e-13	2.89e-52
GO:0043170	macromolecule metabolic process	1073, 1086, 1132, 1195	GO:0015833	peptide transport	941	3.85e-11	1.47e-03
GO:0043170	macromolecule metabolic process	1073, 1086, 1132, 1195	GO:0006811	ion transport	1226	7.11e-80	2.62e-84
GO:0044260	cellular macromolecule metabolic process	989	GO:0015833	peptide transport	941	2.96e-17	2.61e-40
GO:0044260	cellular macromolecule metabolic process	989	GO:0006811	ion transport	1226	4.79e-76	5.35e-109

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MoonDB Network Modules

Biological Processes

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Module ID (MoonGO)	GO ID (BP)	GO Name
941	GO:0015031	protein transport
965	GO:0006139	nucleobase-containing compound metabolic process
989	GO:0016070	RNA metabolic process
989	GO:0010467	gene expression
1014	GO:0034622	cellular macromolecular complex assembly
1014	GO:0006139	nucleobase-containing compound metabolic process
1059	GO:0090304	nucleic acid metabolic process
1073	GO:0010467	gene expression
1086	GO:0010467	gene expression
1132	GO:0010467	gene expression

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Cellular Components

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Module ID (MoonGO)	GO ID (CC)	GO Name
941	GO:0012505	endomembrane system
989	GO:0005634	nucleus
1014	GO:0005634	nucleus
1059	GO:0005634	nucleus
1086	GO:0005634	nucleus
1176	GO:0005634	nucleus
1195	GO:0044428	nuclear part
1307	GO:0012505	endomembrane system
1307	GO:0016021	integral component of membrane
1307	GO:0031984	organelle subcompartment

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Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0015986	ATP synthesis coupled proton transport	IPI
GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly	IMP
GO:0042407	cristae formation	IMP
GO:0099132	ATP hydrolysis coupled cation transmembrane transport	IEA

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Cellular Components

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)	IPI

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 123 entries

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Interactor	Also a MoonDB EMF protein
ACF4_YEAST	No
AIM25_YEAST	No
AIM34_YEAST	No
ALF_YEAST	Yes: P14540 (MoonDB)
ALG13_YEAST	No
AMPL_YEAST	No
AP1_YEAST	No
APA2_YEAST	No
ASP21_YEAST	No
ATP12_YEAST	No

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Publications Associated

Showing 1 to 5 of 5 entries

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PMID	Article Title
8702761	ATP synthase of yeast mitochondria. Isolation of the subunit h and disruption of the ATP14 gene.
9169871	The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
14562106	Global analysis of protein expression in yeast.
17322287	Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
24374639	The reference genome sequence of Saccharomyces cerevisiae: Then and now.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 4 of 4 entries

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Domain Name	Domain ID	Source
ATP_sub_h	PF10775	Pfam
ATP_synth_F0_suH	IPR019711	InterPro
PTHR28207	PTHR28207	PANTHER
S50379	S50379	PIR

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