Skip to main content
A Database of Extreme Multifunctional and Moonlighting Proteins
Main navigation
Home
Browse
Downloads
Help
About
Protein: Q12349
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
Q12349 (Uniprot)
ATP14_YEAST
ATP14
ATP synthase subunit H, mitochondrial
yeast
No
Protein Function
Uniprot:
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembrane
ous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane.
more..
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0044260
cellular macromolecule metabolic process
989
GO:0015833
peptide transport
941
2.96e-17
2.61e-40
GO:0044260
cellular macromolecule metabolic process
989
GO:0006811
ion transport
1226
4.79e-76
5.35e-109
GO:0006139
nucleobase-containing compound metabolic process
1059
GO:0006811
ion transport
1226
1.46e-19
8.47e-83
GO:0043170
macromolecule metabolic process
1073
,
1086
,
1132
,
1195
GO:0015833
peptide transport
941
3.85e-11
1.47e-03
GO:0043170
macromolecule metabolic process
1073
,
1086
,
1132
,
1195
GO:0006811
ion transport
1226
7.11e-80
2.62e-84
GO:0006725
cellular aromatic compound metabolic process
1176
GO:0006811
ion transport
1226
1.93e-19
6.20e-85
GO:0006811
ion transport
1226
GO:0034641
cellular nitrogen compound metabolic process
965
4.44e-27
1.76e-86
GO:0006811
ion transport
1226
GO:0009059
macromolecule biosynthetic process
1258
2.67e-40
7.66e-50
GO:0006811
ion transport
1226
GO:0044249
cellular biosynthetic process
1332
1.64e-27
1.21e-05
GO:0009059
macromolecule biosynthetic process
1258
GO:0015833
peptide transport
941
5.69e-13
2.89e-52
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
941
GO:0015031
protein transport
965
GO:0006139
nucleobase-containing compound metabolic process
989
GO:0016070
RNA metabolic process
989
GO:0010467
gene expression
1014
GO:0034622
cellular macromolecular complex assembly
1014
GO:0006139
nucleobase-containing compound metabolic process
1059
GO:0090304
nucleic acid metabolic process
1073
GO:0010467
gene expression
1086
GO:0010467
gene expression
1132
GO:0010467
gene expression
1132
GO:0006139
nucleobase-containing compound metabolic process
1132
GO:0060255
regulation of macromolecule metabolic process
1176
GO:0006139
nucleobase-containing compound metabolic process
1195
GO:0010467
gene expression
1195
GO:0043933
macromolecular complex subunit organization
1195
GO:0090304
nucleic acid metabolic process
1226
GO:0006820
anion transport
1226
GO:0034654
nucleobase-containing compound biosynthetic process
1258
GO:0034645
cellular macromolecule biosynthetic process
1307
GO:1901566
organonitrogen compound biosynthetic process
1327
GO:0006289
nucleotide-excision repair
1327
GO:0070816
phosphorylation of RNA polymerase II C-terminal domain
1332
GO:0044271
cellular nitrogen compound biosynthetic process
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
941
GO:0012505
endomembrane system
989
GO:0005634
nucleus
1014
GO:0005634
nucleus
1059
GO:0005634
nucleus
1086
GO:0005634
nucleus
1176
GO:0005634
nucleus
1195
GO:0044428
nuclear part
1307
GO:0012505
endomembrane system
1307
GO:0016021
integral component of membrane
1307
GO:0031984
organelle subcompartment
1327
GO:0000439
core TFIIH complex
1327
GO:0005675
holo TFIIH complex
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0015986
ATP synthesis coupled proton transport
IPI
GO:0033615
mitochondrial proton-transporting ATP synthase complex assembly
IMP
GO:0042407
cristae formation
IMP
GO:0099132
ATP hydrolysis coupled cation transmembrane transport
IEA
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0000276
mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)
IPI
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
TF2B_YEAST
Yes:
P29055 (MoonDB)
G3P2_YEAST
Yes:
P00358 (MoonDB)
ACF4_YEAST
No
AIM25_YEAST
No
AIM34_YEAST
No
ALF_YEAST
Yes:
P14540 (MoonDB)
ALG13_YEAST
No
AMPL_YEAST
No
AP1_YEAST
No
APA2_YEAST
No
ASP21_YEAST
No
ATP12_YEAST
No
AYR1_YEAST
No
BET1_YEAST
No
BIT61_YEAST
No
BZRD_YEAST
No
CAB3_YEAST
No
CACM_YEAST
No
CD123_YEAST
No
CIN4_YEAST
No
COA1_YEAST
No
COG3_YEAST
No
COPE_YEAST
No
COQ10_YEAST
No
COX5B_YEAST
No
DFG5_YEAST
No
DID4_YEAST
No
EPS1_YEAST
No
FAD1_YEAST
No
GIS3_YEAST
No
GPP1_YEAST
No
GTR1_YEAST
No
GYP6_YEAST
No
HGH1_YEAST
No
HIS4_YEAST
No
HPH1_YEAST
No
HPM1_YEAST
No
IDHH_YEAST
No
IF4B_YEAST
No
IGD1_YEAST
No
IRC6_YEAST
No
LSB6_YEAST
No
LSM6_YEAST
Yes:
Q06406 (MoonDB)
LTV1_YEAST
No
MDJ2_YEAST
Yes:
P42834 (MoonDB)
MED8_YEAST
No
MFG1_YEAST
No
MMF1_YEAST
No
MMT1_YEAST
No
MTC3_YEAST
No
MTNA_YEAST
No
NACA_YEAST
No
NOP14_YEAST
No
NUP53_YEAST
Yes:
Q03790 (MoonDB)
PBP1_YEAST
No
PCL7_YEAST
No
PGM1_YEAST
No
PNO1_YEAST
No
PRM5_YEAST
No
PRS8_YEAST
No
PRY3_YEAST
No
PSB1_YEAST
No
QCR8_YEAST
No
RAD25_YEAST
No
RL24B_YEAST
No
RLA1_YEAST
No
RMR1_YEAST
No
RPB4_YEAST
No
RRN5_YEAST
No
RUXF_YEAST
No
SEC9_YEAST
No
SERC_YEAST
No
SLX8_YEAST
No
SLX9_YEAST
No
SML1_YEAST
No
SMT3_YEAST
No
SNO3_YEAST
No
SPC29_YEAST
No
SRC1_YEAST
No
SUB1_YEAST
No
SUN4_YEAST
No
TMN1_YEAST
No
TRPF_YEAST
No
UPP_YEAST
No
UPS2_YEAST
No
VATC_YEAST
No
VPS25_YEAST
No
XPT1_YEAST
No
YD118_YEAST
No
YD172_YEAST
No
YD445_YEAST
No
YD455_YEAST
No
YFT2_YEAST
No
YG1O_YEAST
No
YG34_YEAST
No
YG3O_YEAST
No
YGB0_YEAST
No
YHS7_YEAST
No
YHT8_YEAST
No
YHU0_YEAST
No
YID2_YEAST
No
YIF1_YEAST
No
YIF9_YEAST
No
YIM1_YEAST
No
YIW0_YEAST
No
YJ07_YEAST
No
YJ90_YEAST
No
YJ9I_YEAST
No
YJ9S_YEAST
No
YJG7_YEAST
No
YJW5_YEAST
No
YL455_YEAST
No
YL460_YEAST
No
YM21_YEAST
No
YM22_YEAST
No
YM46_YEAST
No
YMH9_YEAST
No
YMY0_YEAST
No
YN64_YEAST
No
YNT4_YEAST
No
YNU5_YEAST
No
YO050_YEAST
No
ZUO1_YEAST
No
Publications Associated
PMID
Article Title
8702761
ATP synthase of yeast mitochondria. Isolation of the subunit h and disruption of the ATP14 gene.
9169871
The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
14562106
Global analysis of protein expression in yeast.
17322287
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
24374639
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
OMIM Diseases Associated
No results found.
Protein Domains Associated
Domain Name
Domain ID
Source
ATP_synth_F0_suH
IPR019711
InterPro
ATP_sub_h
PF10775
Pfam
PTHR28207
PTHR28207
PANTHER
S50379
S50379
PIR