Protein: P42834 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
P42834 (Uniprot)	MDJ2_YEAST	MDJ2	Mitochondrial DnaJ homolog 2	yeast	No

Protein Function

Uniprot: Plays a role in mitochondrial biogenesis and protein folding. Participates in the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner, probably by stimulating activity of mtHSP70 (SSC1).

MoonDB Dissimilar Functions

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0006810	transport	1037	GO:0043170	macromolecule metabolic process	1195	1.58e-118	1.03e-131

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MoonDB Network Modules

Biological Processes

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Module ID (MoonGO)	GO ID (BP)	GO Name
1037	GO:0055085	transmembrane transport
1195	GO:0010467	gene expression
1195	GO:0043933	macromolecular complex subunit organization
1195	GO:0090304	nucleic acid metabolic process

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Cellular Components

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Module ID (MoonGO)	GO ID (CC)	GO Name
1037	GO:0031090	organelle membrane
1195	GO:0044428	nuclear part

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Protein GO Annotations

Biological Processes

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0030150	protein import into mitochondrial matrix	IPI
GO:0032781	positive regulation of ATPase activity	IEA

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Cellular Components

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0001405	presequence translocase-associated import motor	IPI
GO:0005743	mitochondrial inner membrane	IDA

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

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Interactor	Also a MoonDB EMF protein
ATC2_YEAST	No
ATP14_YEAST	Yes: Q12349 (MoonDB)

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Publications Associated

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PMID	Article Title
7645347	Sequencing analysis of a 15.4 kb fragment of yeast chromosome XIV identifies the RPD3, PAS8 and KRE1 loci, five new open reading frames.
9169873	The nucleotide sequence of Saccharomyces cerevisiae chromosome XIV and its evolutionary implications.
9325105	Mdj2p, a novel DnaJ homolog in the mitochondrial inner membrane of the yeast Saccharomyces cerevisiae.
14562095	Global analysis of protein localization in budding yeast.
14562106	Global analysis of protein expression in yeast.
16027163	The import motor of the yeast mitochondrial TIM23 preprotein translocase contains two different J proteins, Tim14 and Mdj2.
17322287	Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
24374639	The reference genome sequence of Saccharomyces cerevisiae: Then and now.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 7 of 7 entries

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Domain Name	Domain ID	Source
DnaJ	SM00271	SMART
DnaJ	cd06257	CDD
DNAJ_2	PS50076	PROSITE
DnaJ_dom_sf	IPR036869	InterPro
DnaJ_domain	IPR001623	InterPro
S55861	S55861	PIR
SSF46565	SSF46565	SUPFAM

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