Protein: P14540

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P14540 (Uniprot) ALF_YEAST FBA1 Fructose-bisphosphate aldolase yeast Yes
Uniprot: Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
Dissimilar Functions Manual Curation

Function 1: Aldolase of the glycolysis pathway.

Function 2: Bind to vacuolar H+ATPase (V-ATPase).

Publications (PMID): 15877277

Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
941 GO:0015031 protein transport
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
941 GO:0012505 endomembrane system
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0006094 gluconeogenesis IMP
GO:0006096 glycolytic process IMP
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0005739 mitochondrion IDA
GO:0005829 cytosol IDA
GO:0005886 plasma membrane IBA
GO:0009277 fungal-type cell wall IBA
No pairs of PrOnto dissimilar CC GO terms found.
Interactor Also a MoonDB EMF protein
ATP14_YEAST Yes: Q12349 (MoonDB)
PMID Article Title
1698168 Cloning of Saccharomyces cerevisiae promoters using a probe vector based on phleomycin resistance.
2647491 Molecular cloning, primary structure and disruption of the structural gene of aldolase from Saccharomyces cerevisiae.
7895733 Protein identifications for a Saccharomyces cerevisiae protein database.
8091862 Sequence of a 28.6 kb region of yeast chromosome XI includes the FBA1 and TOA2 genes, an open reading frame (ORF) similar to a translationally controlled tumour protein, one ORF containing motifs also found in plant storage proteins and 13 ORFs with weak or no homology to known proteins.
8196765 Complete DNA sequence of yeast chromosome XI.
8935650 Protein expression during exponential growth in 0.7 M NaCl medium of Saccharomyces cerevisiae.
14562106 Global analysis of protein expression in yeast.
17287358 Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
17330950 Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
18407956 A multidimensional chromatography technology for in-depth phosphoproteome analysis.
19779198 Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
22106047 Sites of ubiquitin attachment in Saccharomyces cerevisiae.
22814378 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
FBA_II IPR000771 InterPro
Fruct_bisP_bact IPR006411 InterPro
Aldolase_TIM IPR013785 InterPro
F_bP_aldolase PF01116 Pfam
F_bP_aldolase_II PIRSF001359 PIRSF
ALDOLASE_CLASS_II_1 PS00602 PROSITE
ALDOLASE_CLASS_II_2 PS00806 PROSITE
PTHR30559 PTHR30559 PANTHER
ADBY2 S07855 PIR
cbbA TIGR00167 TIGRFAMs
FruBisAldo_II_A TIGR01520 TIGRFAMs
FBP_aldolase_IIA cd00946 CDD