Protein: P62136

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P62136 (Uniprot) PP1A_HUMAN PPP1CA Serine/threonine-protein phosphatase PP1-alpha catalytic subunit human No
Uniprot: Protein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase 1 (PP1) is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. May play an important role in dephosphorylating substrates such as the postsynaptic density-associated Ca(2+)/calmodulin dependent protein kinase II. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Regulates NEK2 function in terms of kinase activity and centrosome number and splitting, both in the presence and absence of radiation-induced DNA damage. Regulator of neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208). Dephosphorylates CENPA (PubMed:25556658). Dephosphorylates the 'Ser-139' residue of ATG16L1 causing dissociation of ATG12-ATG5-ATG16L1 complex, thereby inhibiting autophagy (PubMed:26083323). more..
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0006793 phosphorus metabolic process 491 GO:0009059 macromolecule biosynthetic process 87 1.25e-35 4.53e-23
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
3 GO:0022607 cellular component assembly
3 GO:0060255 regulation of macromolecule metabolic process
24 GO:0016070 RNA metabolic process
24 GO:0006464 cellular protein modification process
24 GO:0034654 nucleobase-containing compound biosynthetic process
24 GO:0006796 phosphate-containing compound metabolic process
24 GO:0031325 positive regulation of cellular metabolic process
24 GO:0010604 positive regulation of macromolecule metabolic process
24 GO:0051173 positive regulation of nitrogen compound metabolic process
24 GO:2000112 regulation of cellular macromolecule biosynthetic process
24 GO:0010468 regulation of gene expression
24 GO:0019219 regulation of nucleobase-containing compound metabolic process
24 GO:0051246 regulation of protein metabolic process
24 GO:0007165 signal transduction
25 GO:0006464 cellular protein modification process
25 GO:0010467 gene expression
25 GO:0060255 regulation of macromolecule metabolic process
25 GO:0007165 signal transduction
26 GO:0006464 cellular protein modification process
26 GO:0090304 nucleic acid metabolic process
26 GO:0010468 regulation of gene expression
87 GO:0034645 cellular macromolecule biosynthetic process
87 GO:0060255 regulation of macromolecule metabolic process
106 GO:0006464 cellular protein modification process
106 GO:0031325 positive regulation of cellular metabolic process
106 GO:0010604 positive regulation of macromolecule metabolic process
106 GO:0051173 positive regulation of nitrogen compound metabolic process
106 GO:0009966 regulation of signal transduction
106 GO:0006355 regulation of transcription, DNA-templated
107 GO:0016070 RNA metabolic process
107 GO:0044267 cellular protein metabolic process
107 GO:0034654 nucleobase-containing compound biosynthetic process
107 GO:2000112 regulation of cellular macromolecule biosynthetic process
107 GO:0010468 regulation of gene expression
107 GO:0019219 regulation of nucleobase-containing compound metabolic process
107 GO:0007165 signal transduction
122 GO:0016070 RNA metabolic process
122 GO:0044271 cellular nitrogen compound biosynthetic process
122 GO:0006464 cellular protein modification process
122 GO:0031324 negative regulation of cellular metabolic process
122 GO:0010605 negative regulation of macromolecule metabolic process
122 GO:0051172 negative regulation of nitrogen compound metabolic process
122 GO:2000112 regulation of cellular macromolecule biosynthetic process
122 GO:0010468 regulation of gene expression
122 GO:0019219 regulation of nucleobase-containing compound metabolic process
122 GO:0007165 signal transduction
134 GO:0044267 cellular protein metabolic process
134 GO:0060255 regulation of macromolecule metabolic process
134 GO:0007165 signal transduction
165 GO:0006464 cellular protein modification process
165 GO:0070887 cellular response to chemical stimulus
165 GO:0031325 positive regulation of cellular metabolic process
165 GO:0010604 positive regulation of macromolecule metabolic process
165 GO:0051173 positive regulation of nitrogen compound metabolic process
165 GO:0051246 regulation of protein metabolic process
165 GO:0006355 regulation of transcription, DNA-templated
165 GO:0007165 signal transduction
169 GO:0030522 intracellular receptor signaling pathway
169 GO:0045892 negative regulation of transcription, DNA-templated
169 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
169 GO:0043401 steroid hormone mediated signaling pathway
175 GO:0044267 cellular protein metabolic process
175 GO:0006139 nucleobase-containing compound metabolic process
175 GO:0010468 regulation of gene expression
181 GO:0044267 cellular protein metabolic process
181 GO:0010467 gene expression
181 GO:0009059 macromolecule biosynthetic process
181 GO:0090304 nucleic acid metabolic process
181 GO:0060255 regulation of macromolecule metabolic process
181 GO:0007165 signal transduction
292 GO:0044267 cellular protein metabolic process
292 GO:0010467 gene expression
330 GO:0006464 cellular protein modification process
330 GO:0006796 phosphate-containing compound metabolic process
330 GO:0031325 positive regulation of cellular metabolic process
330 GO:0010604 positive regulation of macromolecule metabolic process
330 GO:0051173 positive regulation of nitrogen compound metabolic process
330 GO:2000112 regulation of cellular macromolecule biosynthetic process
330 GO:0010468 regulation of gene expression
330 GO:0019219 regulation of nucleobase-containing compound metabolic process
330 GO:0051246 regulation of protein metabolic process
330 GO:0007165 signal transduction
330 GO:0006351 transcription, DNA-templated
357 GO:0071310 cellular response to organic substance
357 GO:0031324 negative regulation of cellular metabolic process
357 GO:0010605 negative regulation of macromolecule metabolic process
357 GO:0051172 negative regulation of nitrogen compound metabolic process
357 GO:0031325 positive regulation of cellular metabolic process
357 GO:0010604 positive regulation of macromolecule metabolic process
357 GO:0051173 positive regulation of nitrogen compound metabolic process
357 GO:0009966 regulation of signal transduction
357 GO:0006357 regulation of transcription from RNA polymerase II promoter
362 GO:0006464 cellular protein modification process
362 GO:0060255 regulation of macromolecule metabolic process
380 GO:0010467 gene expression
380 GO:0019538 protein metabolic process
380 GO:0060255 regulation of macromolecule metabolic process
413 GO:0044267 cellular protein metabolic process
413 GO:0031326 regulation of cellular biosynthetic process
413 GO:0010468 regulation of gene expression
413 GO:0010556 regulation of macromolecule biosynthetic process
413 GO:0007165 signal transduction
413 GO:0006351 transcription, DNA-templated
482 GO:0006464 cellular protein modification process
482 GO:0007167 enzyme linked receptor protein signaling pathway
482 GO:0006796 phosphate-containing compound metabolic process
482 GO:0032268 regulation of cellular protein metabolic process
482 GO:0009966 regulation of signal transduction
490 GO:0031325 positive regulation of cellular metabolic process
490 GO:0010604 positive regulation of macromolecule metabolic process
490 GO:0051173 positive regulation of nitrogen compound metabolic process
490 GO:0009966 regulation of signal transduction
490 GO:0006357 regulation of transcription from RNA polymerase II promoter
491 GO:0006796 phosphate-containing compound metabolic process
516 GO:0019538 protein metabolic process
521 GO:0060255 regulation of macromolecule metabolic process
534 GO:0007166 cell surface receptor signaling pathway
534 GO:0006464 cellular protein modification process
534 GO:0033554 cellular response to stress
534 GO:0010467 gene expression
534 GO:0006796 phosphate-containing compound metabolic process
534 GO:0060255 regulation of macromolecule metabolic process
534 GO:0009966 regulation of signal transduction
534 GO:0009628 response to abiotic stimulus
547 GO:0060255 regulation of macromolecule metabolic process
549 GO:0008219 cell death
549 GO:0070887 cellular response to chemical stimulus
549 GO:0033554 cellular response to stress
549 GO:0035556 intracellular signal transduction
549 GO:0031325 positive regulation of cellular metabolic process
549 GO:0010604 positive regulation of macromolecule metabolic process
549 GO:0051173 positive regulation of nitrogen compound metabolic process
549 GO:0048584 positive regulation of response to stimulus
549 GO:0006468 protein phosphorylation
549 GO:0051252 regulation of RNA metabolic process
549 GO:2000112 regulation of cellular macromolecule biosynthetic process
549 GO:0032268 regulation of cellular protein metabolic process
549 GO:0010468 regulation of gene expression
549 GO:0009966 regulation of signal transduction
549 GO:0006351 transcription, DNA-templated
577 GO:0006464 cellular protein modification process
577 GO:0033554 cellular response to stress
577 GO:0006796 phosphate-containing compound metabolic process
577 GO:0031326 regulation of cellular biosynthetic process
577 GO:0010556 regulation of macromolecule biosynthetic process
577 GO:0009966 regulation of signal transduction
610 GO:0008219 cell death
610 GO:0007166 cell surface receptor signaling pathway
610 GO:0006464 cellular protein modification process
610 GO:0031324 negative regulation of cellular metabolic process
610 GO:0051172 negative regulation of nitrogen compound metabolic process
610 GO:0016310 phosphorylation
610 GO:0010604 positive regulation of macromolecule metabolic process
610 GO:0051173 positive regulation of nitrogen compound metabolic process
610 GO:0008104 protein localization
610 GO:0051128 regulation of cellular component organization
610 GO:0032268 regulation of cellular protein metabolic process
610 GO:0009966 regulation of signal transduction
610 GO:0006355 regulation of transcription, DNA-templated
629 GO:0007165 signal transduction
668 GO:0006464 cellular protein modification process
668 GO:0006796 phosphate-containing compound metabolic process
674 GO:0006464 cellular protein modification process
674 GO:0031324 negative regulation of cellular metabolic process
674 GO:0010605 negative regulation of macromolecule metabolic process
674 GO:0051172 negative regulation of nitrogen compound metabolic process
674 GO:0010604 positive regulation of macromolecule metabolic process
674 GO:2000112 regulation of cellular macromolecule biosynthetic process
674 GO:0010468 regulation of gene expression
674 GO:1903506 regulation of nucleic acid-templated transcription
674 GO:0007165 signal transduction
674 GO:0006351 transcription, DNA-templated
705 GO:0060255 regulation of macromolecule metabolic process
706 GO:0044267 cellular protein metabolic process
706 GO:0090304 nucleic acid metabolic process
706 GO:0034654 nucleobase-containing compound biosynthetic process
706 GO:2000112 regulation of cellular macromolecule biosynthetic process
706 GO:0010468 regulation of gene expression
706 GO:0019219 regulation of nucleobase-containing compound metabolic process
706 GO:0007165 signal transduction
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
3 GO:0044430 cytoskeletal part
3 GO:0005829 cytosol
3 GO:0005634 nucleus
24 GO:0005829 cytosol
24 GO:0005654 nucleoplasm
25 GO:0005829 cytosol
25 GO:0005634 nucleus
26 GO:0005654 nucleoplasm
87 GO:0005634 nucleus
105 GO:0005634 nucleus
106 GO:0005829 cytosol
106 GO:0005654 nucleoplasm
107 GO:0005829 cytosol
107 GO:0005654 nucleoplasm
122 GO:0005829 cytosol
122 GO:0043232 intracellular non-membrane-bounded organelle
122 GO:0005654 nucleoplasm
134 GO:0005829 cytosol
134 GO:0005634 nucleus
165 GO:0005829 cytosol
165 GO:0043232 intracellular non-membrane-bounded organelle
165 GO:0005654 nucleoplasm
169 GO:0005654 nucleoplasm
175 GO:0005829 cytosol
175 GO:0005634 nucleus
181 GO:0005829 cytosol
181 GO:0005654 nucleoplasm
190 GO:0005829 cytosol
190 GO:0043232 intracellular non-membrane-bounded organelle
292 GO:0043232 intracellular non-membrane-bounded organelle
292 GO:0031981 nuclear lumen
317 GO:0005829 cytosol
328 GO:0005829 cytosol
328 GO:0043232 intracellular non-membrane-bounded organelle
328 GO:0005654 nucleoplasm
330 GO:0005829 cytosol
330 GO:0005654 nucleoplasm
357 GO:0005654 nucleoplasm
361 GO:0005829 cytosol
362 GO:0070013 intracellular organelle lumen
362 GO:0005634 nucleus
380 GO:0005634 nucleus
413 GO:0005654 nucleoplasm
443 GO:0005829 cytosol
443 GO:0005634 nucleus
482 GO:0005576 extracellular region
490 GO:0005654 nucleoplasm
491 GO:0005829 cytosol
491 GO:0043232 intracellular non-membrane-bounded organelle
491 GO:0005634 nucleus
516 GO:0005634 nucleus
521 GO:0070013 intracellular organelle lumen
521 GO:0005634 nucleus
534 GO:0005829 cytosol
534 GO:0012505 endomembrane system
534 GO:0005654 nucleoplasm
547 GO:0005654 nucleoplasm
549 GO:0005829 cytosol
549 GO:0005634 nucleus
577 GO:0005829 cytosol
577 GO:0043232 intracellular non-membrane-bounded organelle
577 GO:0070013 intracellular organelle lumen
577 GO:0044428 nuclear part
577 GO:0031982 vesicle
610 GO:0031981 nuclear lumen
629 GO:0005829 cytosol
629 GO:0031982 vesicle
674 GO:0005829 cytosol
674 GO:0043232 intracellular non-membrane-bounded organelle
674 GO:0005654 nucleoplasm
705 GO:0070013 intracellular organelle lumen
706 GO:0005829 cytosol
706 GO:0031981 nuclear lumen
739 GO:0043232 intracellular non-membrane-bounded organelle
739 GO:0005654 nucleoplasm
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0005977 glycogen metabolic process IEA
GO:0006470 protein dephosphorylation IMP
GO:0007049 cell cycle IEA
GO:0016311 dephosphorylation IDA
GO:0032091 negative regulation of protein binding ISS
GO:0032922 circadian regulation of gene expression ISS
GO:0036496 regulation of translational initiation by eIF2 alpha dephosphorylation ISS
GO:0042752 regulation of circadian rhythm IMP
GO:0043153 entrainment of circadian clock by photoperiod ISS
GO:0051301 cell division IEA
GO:0060828 regulation of canonical Wnt signaling pathway IC
GO:0098609 cell-cell adhesion IEA
GO:1904886 beta-catenin destruction complex disassembly ISS
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0000784 nuclear chromosome, telomeric region IDA
GO:0005634 nucleus IDA
GO:0005654 nucleoplasm IDA
GO:0005730 nucleolus IEA
GO:0005737 cytoplasm IDA
GO:0005829 cytosol TAS
GO:0005886 plasma membrane IDA
GO:0005913 cell-cell adherens junction IDA
GO:0070062 extracellular exosome IDA
GO:0072357 PTW/PP1 phosphatase complex IDA
GO ID 1 Component 1 GO ID 2 Component 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0000784 nuclear chromosome, telomeric region GO:0005886 plasma membrane 2.99e-06 4.16e-73
GO:0005634 nucleus GO:0005886 plasma membrane 5.35e-300 7.52e-165
GO:0005634 nucleus GO:0070062 extracellular exosome 6.30e-13 4.54e-26
GO:0005654 nucleoplasm GO:0005886 plasma membrane 9.14e-199 6.17e-196
GO:0005654 nucleoplasm GO:0070062 extracellular exosome 3.37e-20 1.23e-35
GO:0005730 nucleolus GO:0005886 plasma membrane 7.70e-47 3.09e-07
Interactor Also a MoonDB EMF protein
ASPP2_HUMAN No
SKP1_HUMAN Yes: P63208 (MoonDB)
PPR18_HUMAN No
BHE40_HUMAN Yes: O14503 (MoonDB)
A1DRY3_HUMAN No
PP1G_HUMAN Yes: P36873 (MoonDB)
2A5E_HUMAN No
A0A0A0MT80_HUMAN No
AKT1_HUMAN No
APAF_HUMAN No
ASPP1_HUMAN No
ATD3A_HUMAN No
ATM_HUMAN No
AURKB_HUMAN No
B2CL1_HUMAN No
BCL2_HUMAN No
BTBDA_HUMAN No
C1QA_HUMAN No
CADH1_HUMAN No
CC181_HUMAN No
CC85B_HUMAN No
CC85C_HUMAN No
CD2B2_HUMAN No
CDK1_HUMAN No
CDK2_HUMAN No
CDK4_HUMAN No
CE126_HUMAN No
CE170_HUMAN No
CHERP_HUMAN Yes: Q8IWX8 (MoonDB)
CLCN2_HUMAN No
CLH1_HUMAN Yes: Q00610 (MoonDB)
CLOCK_HUMAN No
CN37_HUMAN No
CNST_HUMAN No
CNTN1_HUMAN No
CRK_HUMAN Yes: P46108 (MoonDB)
CSK2B_HUMAN Yes: P67870 (MoonDB)
CSRN1_HUMAN No
CSRN2_HUMAN No
CXXC1_HUMAN No
DCTN1_HUMAN No
DEAF1_HUMAN No
DEC1_HUMAN No
ERBIN_HUMAN No
FRPD4_HUMAN No
GPKOW_HUMAN No
GRPL2_HUMAN No
GYS1_HUMAN No
HEYL_HUMAN No
IASPP_HUMAN No
IBTK_HUMAN No
IPP2M_HUMAN No
IPP2_HUMAN No
IPP4_HUMAN No
JPH3_HUMAN No
KANK1_HUMAN No
KCD20_HUMAN No
KCRB_HUMAN No
KI18A_HUMAN No
KNL1_HUMAN No
LARGN_HUMAN No
LMTK1_HUMAN No
LMTK2_HUMAN No
LPIN2_HUMAN No
LRRK2_HUMAN No
M4K4_HUMAN No
MAFG_HUMAN No
MAL2_HUMAN No
MAX_HUMAN No
MIIP_HUMAN No
MK01_HUMAN Yes: P28482 (MoonDB)
MK03_HUMAN Yes: P27361 (MoonDB)
MPP10_HUMAN No
NDP_HUMAN No
NEB2_HUMAN No
NEK2_HUMAN No
NINL_HUMAN No
NOM1_HUMAN No
NOP53_HUMAN No
P53_HUMAN Yes: P04637 (MoonDB)
PARD3_HUMAN No
PDRG1_HUMAN No
PEAK1_HUMAN No
PFD2_HUMAN No
PFD6_HUMAN No
PHAR1_HUMAN No
PHAR3_HUMAN No
PHC1_HUMAN No
PIAS1_HUMAN No
PIAS3_HUMAN No
PIHD1_HUMAN No
PLCL2_HUMAN No
PP13G_HUMAN No
PP16A_HUMAN No
PP1R7_HUMAN No
PP1R8_HUMAN No
PP1RA_HUMAN No
PP1RB_HUMAN No
PPR26_HUMAN No
PPR27_HUMAN No
PPR32_HUMAN No
PPR37_HUMAN No
PPR3B_HUMAN No
PPR3C_HUMAN No
PPR3D_HUMAN No
PPR3E_HUMAN No
PR15A_HUMAN No
PR15B_HUMAN No
PREX1_HUMAN No
PTEN_HUMAN No
RANB9_HUMAN No
RASF7_HUMAN No
RASF8_HUMAN No
RB_HUMAN No
RIF1_HUMAN No
RMP_HUMAN No
RORG_HUMAN No
RPAB1_HUMAN No
RPAP3_HUMAN No
RPC1_HUMAN No
RPRD2_HUMAN No
RUVB1_HUMAN No
RUVB2_HUMAN No
RYR1_HUMAN No
S45A1_HUMAN No
SAR1A_HUMAN No
SFRP1_HUMAN No
SH3R2_HUMAN No
SNCAP_HUMAN No
SORL_HUMAN No
SPRE1_HUMAN No
STAM1_HUMAN No
STAU1_HUMAN No
SYTL2_HUMAN No
TC1D4_HUMAN No
TCPZ_HUMAN No
TOE1_HUMAN No
TOIP1_HUMAN No
TOX4_HUMAN No
TPRN_HUMAN No
TUSC3_HUMAN No
UBE2Z_HUMAN No
ULK1_HUMAN No
UXT_HUMAN No
WBP11_HUMAN No
WDR82_HUMAN No
WDR92_HUMAN No
YLPM1_HUMAN No
ZBT11_HUMAN No
ZFY16_HUMAN No
ZFYV9_HUMAN No
ZN827_HUMAN No
PMID Article Title
2161401 Localization of the gene encoding a type I protein phosphatase catalytic subunit to human chromosome band 11q13.
8384581 The retinoblastoma protein associates with the protein phosphatase type 1 catalytic subunit.
8392016 Cloning and characterization of a human protein phosphatase 1-encoding cDNA.
9023344 The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase.
11564868 Growth arrest and DNA damage-inducible protein GADD34 assembles a novel signaling complex containing protein phosphatase 1 and inhibitor 1.
11739654 Dynamic targeting of protein phosphatase 1 within the nuclei of living mammalian cells.
11839776 Protein phosphatase 1 -- targeted in many directions.
12226088 Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.
14702039 Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15705855 A selective inhibitor of eIF2alpha dephosphorylation protects cells from ER stress.
16263087 The protein phosphatase-1 targeting subunit TIMAP regulates LAMR1 phosphorylation.
16554811 Human chromosome 11 DNA sequence and analysis including novel gene identification.
16732323 Downregulation of Fer induces PP1 activation and cell-cycle arrest in malignant cells.
17283141 Protein phosphatase-1alpha regulates centrosome splitting through Nek2.
17626005 Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase.
17890166 The nuclear PP1 interacting protein ZAP3 (ZAP) is a putative nucleoside kinase that complexes with SAM68, CIA, NF110/45, and HNRNP-G.
17965019 NOM1 targets protein phosphatase I to the nucleolus.
18088087 Phosphoproteome of resting human platelets.
18669648 A quantitative atlas of mitotic phosphorylation.
18992256 Crystal structures of protein phosphatase-1 bound to nodularin-R and tautomycin: a novel scaffold for structure-based drug design of serine/threonine phosphatase inhibitors.
19377461 GlcNAcylation of a histone methyltransferase in retinoic-acid-induced granulopoiesis.
19581931 Dab2 stabilizes Axin and attenuates Wnt/beta-catenin signaling by preventing protein phosphatase 1 (PP1)-Axin interactions.
20068231 Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
20305656 Spinophilin directs protein phosphatase 1 specificity by blocking substrate binding sites.
20424263 SUMOylation of the transcriptional co-repressor KAP1 is regulated by the serine and threonine phosphatase PP1.
20516061 Identification and characterization of a novel human PP1 phosphatase complex.
21269460 Initial characterization of the human central proteome.
21712997 Protein phosphatase 1 (PP1) is a post-translational regulator of the mammalian circadian clock.
22814378 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
23186163 Toward a comprehensive characterization of a human cancer cell phosphoproteome.
23396208 Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-alpha in rheumatoid arthritis.
25556658 Dynamic phosphorylation of CENP-A at Ser68 orchestrates its cell-cycle-dependent deposition at centromeres.
25944712 N-terminome analysis of the human mitochondrial proteome.
26083323 ATG16L1 phosphorylation is oppositely regulated by CSNK2/casein kinase 2 and PPP1/protein phosphatase 1 which determines the fate of cardiomyocytes during hypoxia/reoxygenation.
No results found.
Domain Name Domain ID Source
Calcineurin-like_PHP_ApaH IPR004843 InterPro
Ser/Thr-sp_prot-phosphatase IPR006186 InterPro
Metallo-depent_PP-like IPR029052 InterPro
STPPase_N IPR031675 InterPro
Metallophos PF00149 Pfam
STPPase_N PF16891 Pfam
STPHPHTASE PR00114 PRINTS
SER_THR_PHOSPHATASE PS00125 PROSITE
PP2Ac SM00156 SMART
SSF56300 SSF56300 SUPFAM