Protein: P37370 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
P37370 (Uniprot)	VRP1_YEAST	VRP1	Verprolin	yeast	No

Protein Function

Uniprot: Involved in cytoskeletal organization and cellular growth. May exert its effects on the cytoskeleton directly, or indirectly via proline-binding proteins (e.g. profilin) or proteins possessing SH3 domains.

MoonDB Dissimilar Functions

Showing 1 to 1 of 1 entries

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GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0097435	supramolecular fiber organization	1177, 1242	GO:0006725	cellular aromatic compound metabolic process	962	4.17e-09	4.54e-39

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MoonDB Network Modules

Biological Processes

Showing 1 to 10 of 11 entries

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Module ID (MoonGO)	GO ID (BP)	GO Name
962	GO:0006139	nucleobase-containing compound metabolic process
1177	GO:0007015	actin filament organization
1177	GO:0022607	cellular component assembly
1177	GO:0044087	regulation of cellular component biogenesis
1177	GO:0033043	regulation of organelle organization
1242	GO:0051666	actin cortical patch localization
1242	GO:0007015	actin filament organization
1242	GO:0034622	cellular macromolecular complex assembly
1242	GO:0006897	endocytosis
1242	GO:1903047	mitotic cell cycle process

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Cellular Components

Showing 1 to 3 of 3 entries

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Module ID (MoonGO)	GO ID (CC)	GO Name
1177	GO:0005856	cytoskeleton
1177	GO:0005634	nucleus
1242	GO:0030479	actin cortical patch

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Protein GO Annotations

Biological Processes

Showing 1 to 5 of 5 entries

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0006897	endocytosis	IMP
GO:0007121	bipolar cellular bud site selection	IMP
GO:0032465	regulation of cytokinesis	IMP
GO:0051666	actin cortical patch localization	IMP
GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	IDA

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Cellular Components

Showing 1 to 3 of 3 entries

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0000131	incipient cellular bud site	IDA
GO:0005935	cellular bud neck	IDA
GO:0030479	actin cortical patch	IDA

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 8 of 8 entries

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Interactor	Also a MoonDB EMF protein
ACT_YEAST	Yes: P60010 (MoonDB)
ASG1_YEAST	No
BBC1_YEAST	Yes: P47068 (MoonDB)
CYK2_YEAST	Yes: Q05080 (MoonDB)
LAS17_YEAST	No
MYO3_YEAST	Yes: P36006 (MoonDB)
MYO5_YEAST	Yes: Q04439 (MoonDB)
RV167_YEAST	Yes: P39743 (MoonDB)

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Publications Associated

Showing 1 to 7 of 7 entries

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PMID	Article Title
7968536	A proline-rich protein, verprolin, involved in cytoskeletal organization and cellular growth in the yeast Saccharomyces cerevisiae.
9169871	The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
14562095	Global analysis of protein localization in budding yeast.
18407956	A multidimensional chromatography technology for in-depth phosphoproteome analysis.
19756047	Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes.
19779198	Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
24374639	The reference genome sequence of Saccharomyces cerevisiae: Then and now.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 5 of 5 entries

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Domain Name	Domain ID	Source
S51342	S51342	PIR
WH2	PF02205	Pfam
WH2	PS51082	PROSITE
WH2	SM00246	SMART
WH2_dom	IPR003124	InterPro

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