Protein: Q05080

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
Q05080 (Uniprot) CYK2_YEAST HOF1 Cytokinesis protein 2 yeast No
Uniprot: Throughout most of the cell cycle it forms a double ring that coincides with the septins. After the onset of mitosis, forms a ring-like structure which colocalizes with the medial actin ring. Mediates cytoskeletal rearrangements required for cytokinesis. In conjunction with the medial actin ring exhibits contraction-like action. more..
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0044260 cellular macromolecule metabolic process 1018 GO:0097435 supramolecular fiber organization 1177 6.22e-07 4.50e-41
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
932 GO:0016070 RNA metabolic process
932 GO:0010467 gene expression
1018 GO:0016070 RNA metabolic process
1018 GO:0010468 regulation of gene expression
1177 GO:0007015 actin filament organization
1177 GO:0022607 cellular component assembly
1177 GO:0044087 regulation of cellular component biogenesis
1177 GO:0033043 regulation of organelle organization
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
932 GO:0005634 nucleus
948 GO:0043232 intracellular non-membrane-bounded organelle
954 GO:0043232 intracellular non-membrane-bounded organelle
958 GO:0005935 cellular bud neck
980 GO:0005634 nucleus
1000 GO:0005634 nucleus
1018 GO:0043232 intracellular non-membrane-bounded organelle
1018 GO:0005634 nucleus
1165 GO:0016021 integral component of membrane
1177 GO:0005856 cytoskeleton
1177 GO:0005634 nucleus
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0000281 mitotic cytokinesis IMP
GO:0000917 division septum assembly IMP
GO:0090339 negative regulation of formin-nucleated actin cable assembly IMP
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0000142 cellular bud neck contractile ring IDA
GO:0000144 cellular bud neck septin ring IDA
GO:0005935 cellular bud neck IDA
GO:0044697 HICS complex IPI
No pairs of PrOnto dissimilar CC GO terms found.
PMID Article Title
9169872 The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.
9864366 Dual function of Cyk2, a cdc15/PSTPIP family protein, in regulating actomyosin ring dynamics and septin distribution.
14562106 Global analysis of protein expression in yeast.
18344988 Inn1 couples contraction of the actomyosin ring to membrane ingression during cytokinesis in budding yeast.
18407956 A multidimensional chromatography technology for in-depth phosphoproteome analysis.
19528296 Role of Inn1 and its interactions with Hof1 and Cyk3 in promoting cleavage furrow and septum formation in S. cerevisiae.
19779198 Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
FCH_dom IPR001060 InterPro
SH3_domain IPR001452 InterPro
AH/BAR_dom_sf IPR027267 InterPro
F_BAR IPR031160 InterPro
SH3-like_dom_sf IPR036028 InterPro
FCH PF00611 Pfam
SH3 PS50002 PROSITE
F_BAR PS51741 PROSITE
S53948 S53948 PIR
FCH SM00055 SMART
SH3 SM00326 SMART
SSF103657 SSF103657 SUPFAM
SSF50044 SSF50044 SUPFAM