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A Database of Extreme Multifunctional and Moonlighting Proteins
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About
Protein: P47068
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
P47068 (Uniprot)
BBC1_YEAST
BBC1
Myosin tail region-interacting protein MTI1
yeast
No
Protein Function
Uniprot:
Involved in the regulation of actin cytoskeleton.
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0009059
macromolecule biosynthetic process
1121
GO:0097435
supramolecular fiber organization
1177
2.11e-07
3.47e-31
GO:0097435
supramolecular fiber organization
1177
GO:0044260
cellular macromolecule metabolic process
932
6.22e-07
4.50e-41
GO:0097435
supramolecular fiber organization
1177
GO:0043170
macromolecule metabolic process
1300
4.36e-08
1.57e-47
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
932
GO:0016070
RNA metabolic process
932
GO:0010467
gene expression
1121
GO:0034645
cellular macromolecule biosynthetic process
1121
GO:0044271
cellular nitrogen compound biosynthetic process
1121
GO:0010467
gene expression
1121
GO:0090304
nucleic acid metabolic process
1177
GO:0007015
actin filament organization
1177
GO:0022607
cellular component assembly
1177
GO:0044087
regulation of cellular component biogenesis
1177
GO:0033043
regulation of organelle organization
1300
GO:0010467
gene expression
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
884
GO:0043232
intracellular non-membrane-bounded organelle
932
GO:0005634
nucleus
954
GO:0043232
intracellular non-membrane-bounded organelle
1121
GO:0005634
nucleus
1140
GO:0005634
nucleus
1177
GO:0005856
cytoskeleton
1177
GO:0005634
nucleus
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0007010
cytoskeleton organization
IGI
GO:0030036
actin cytoskeleton organization
IPI
GO:0034316
negative regulation of Arp2/3 complex-mediated actin nucleation
IDA
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0030479
actin cortical patch
IDA
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
MYO3_YEAST
Yes:
P36006 (MoonDB)
SSN8_YEAST
No
LSM8_YEAST
No
CYK2_YEAST
Yes:
Q05080 (MoonDB)
BZZ1_YEAST
Yes:
P38822 (MoonDB)
MYO5_YEAST
Yes:
Q04439 (MoonDB)
KPC1_YEAST
No
FIR1_YEAST
No
PCL6_YEAST
No
YRF13_YEAST
No
TGL5_YEAST
No
THDH_YEAST
No
2AAA_YEAST
No
2ABA_YEAST
No
2NDP_YEAST
No
ACAC_YEAST
No
AIM21_YEAST
No
AIM3_YEAST
No
APP1_YEAST
No
ATC8_YEAST
No
BNR1_YEAST
No
CDC6_YEAST
No
ENT2_YEAST
No
FAP1_YEAST
No
GCR2_YEAST
No
GDE_YEAST
No
HAP4_YEAST
No
HRQ1_YEAST
No
IF5A2_YEAST
No
IME2_YEAST
No
KAR9_YEAST
No
KEG1_YEAST
No
LAS17_YEAST
No
LRG1_YEAST
No
MIC19_YEAST
No
MIG1_YEAST
No
MTH1_YEAST
No
MUS81_YEAST
No
NDC80_YEAST
No
NOT5_YEAST
No
PBS2_YEAST
No
PEX13_YEAST
No
PIF1_YEAST
No
RL19A_YEAST
No
RMR1_YEAST
No
RRP7_YEAST
No
RS26A_YEAST
No
RS26B_YEAST
No
RT106_YEAST
No
SIZ1_YEAST
No
SIZ2_YEAST
No
SNF2_YEAST
No
SPR6_YEAST
No
STD1_YEAST
No
STE20_YEAST
No
UFD1_YEAST
No
VRP1_YEAST
Yes:
P37370 (MoonDB)
YD129_YEAST
No
YHY2_YEAST
No
YJ85_YEAST
No
YJL8_YEAST
No
YJT5_YEAST
No
YJZ3_YEAST
No
YN93_YEAST
No
YP091_YEAST
No
YP245_YEAST
No
Publications Associated
PMID
Article Title
8641269
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X.
11901111
The novel adaptor protein, Mti1p, and Vrp1p, a homolog of Wiskott-Aldrich syndrome protein-interacting protein (WIP), may antagonistically regulate type I myosins in Saccharomyces cerevisiae.
15665377
Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
17287358
Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.
17330950
Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
18407956
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
19779198
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
22106047
Sites of ubiquitin attachment in Saccharomyces cerevisiae.
24374639
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
OMIM Diseases Associated
No results found.
Protein Domains Associated
Domain Name
Domain ID
Source
SH3_domain
IPR001452
InterPro
Mti1_SH3
IPR035552
InterPro
SH3-like_dom_sf
IPR036028
InterPro
SH3_1
PF00018
Pfam
SH3
PS50002
PROSITE
S56791
S56791
PIR
S56792
S56792
PIR
SH3
SM00326
SMART
SSF50044
SSF50044
SUPFAM
SH3_Bbc1
cd11887
CDD