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A Database of Extreme Multifunctional and Moonlighting Proteins
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About
Protein: P38822
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
P38822 (Uniprot)
BZZ1_YEAST
BZZ1
Protein BZZ1
yeast
No
Protein Function
Uniprot:
Plays a role in endocytosis and trafficking to the vacuole. Functions with type I myosins to restore polarity of the actin cytoskeleton after NaCl stress.
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0034641
cellular nitrogen compound metabolic process
1024
GO:0006810
transport
936
1.51e-114
6.30e-204
GO:0090304
nucleic acid metabolic process
1135
GO:0006810
transport
936
2.35e-98
2.13e-244
GO:0043170
macromolecule metabolic process
1300
GO:0006810
transport
936
1.58e-118
1.03e-131
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
936
GO:0071705
nitrogen compound transport
1024
GO:0006139
nucleobase-containing compound metabolic process
1135
GO:0016070
RNA metabolic process
1135
GO:0010467
gene expression
1300
GO:0010467
gene expression
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
884
GO:0043232
intracellular non-membrane-bounded organelle
936
GO:0016021
integral component of membrane
936
GO:0031090
organelle membrane
954
GO:0043232
intracellular non-membrane-bounded organelle
1012
GO:0043232
intracellular non-membrane-bounded organelle
1135
GO:0005634
nucleus
1187
GO:0005634
nucleus
1211
GO:0005634
nucleus
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0006897
endocytosis
IGI
GO:0007015
actin filament organization
IPI
GO:0009651
response to salt stress
IPI
GO:0043085
positive regulation of catalytic activity
IEA
GO:0045010
actin nucleation
IMP
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005886
plasma membrane
IDA
GO:0030479
actin cortical patch
IDA
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
MYO3_YEAST
Yes:
P36006 (MoonDB)
CSM2_YEAST
No
PSA2_YEAST
No
PAU4_YEAST
No
2ABA_YEAST
No
ABM1_YEAST
No
ACAC_YEAST
No
AIM21_YEAST
No
AIM3_YEAST
No
ALE1_YEAST
No
ALG10_YEAST
No
APC2_YEAST
No
APE2_YEAST
No
APP1_YEAST
No
ARGI_YEAST
No
ARPC2_YEAST
No
ATC8_YEAST
No
ATG19_YEAST
No
ATG3_YEAST
No
ATP12_YEAST
No
ATU2_YEAST
No
BBC1_YEAST
Yes:
P47068 (MoonDB)
BOS1_YEAST
No
BSC1_YEAST
No
BSP1_YEAST
No
CAPZA_YEAST
No
CARME_YEAST
No
CLD1_YEAST
No
CSE1_YEAST
No
CTH2_YEAST
No
CUL8_YEAST
No
DAL81_YEAST
No
DIG1_YEAST
No
DIG2_YEAST
No
DLDH_YEAST
No
DLS1_YEAST
No
DS1P1_YEAST
No
ECO1_YEAST
No
EDC1_YEAST
No
END3_YEAST
No
ERG24_YEAST
No
ERG6_YEAST
No
FIR1_YEAST
No
FUS2_YEAST
No
GAL2_YEAST
No
GDS1_YEAST
No
GET3_YEAST
No
GMH1_YEAST
No
GMT1_YEAST
No
GRR1_YEAST
No
GTR1_YEAST
No
GTT3_YEAST
No
HS150_YEAST
No
IMH1_YEAST
No
IMO32_YEAST
No
INP53_YEAST
No
IZH2_YEAST
No
JAC1_YEAST
No
KRE9_YEAST
No
KTR3_YEAST
No
LAS17_YEAST
No
LDB17_YEAST
No
LDS1_YEAST
No
LSB5_YEAST
No
MCFS2_YEAST
No
MCM6_YEAST
No
MKK1_YEAST
No
MPT5_YEAST
No
MRS1_YEAST
No
MTH1_YEAST
No
MTO1_YEAST
No
MYO5_YEAST
Yes:
Q04439 (MoonDB)
NCB1_YEAST
No
NDC80_YEAST
No
NHP6A_YEAST
No
NIP80_YEAST
No
NIS1_YEAST
No
NOP6_YEAST
No
NOP9_YEAST
No
NSG1_YEAST
No
ODO2_YEAST
No
PDR11_YEAST
No
PER1_YEAST
No
PER33_YEAST
No
PEX30_YEAST
No
PEX31_YEAST
No
PHO86_YEAST
No
PIG2_YEAST
No
PLP2_YEAST
No
PNC1_YEAST
No
PP2A1_YEAST
No
PPQ1_YEAST
No
PRP21_YEAST
No
PTPA2_YEAST
No
QCR7_YEAST
No
RBD2_YEAST
No
RDS3_YEAST
No
RIM2_YEAST
No
RL19A_YEAST
No
RL23A_YEAST
No
RL30_YEAST
No
RNQ1_YEAST
No
RPAB3_YEAST
No
RRP43_YEAST
No
RRP7_YEAST
No
RS26A_YEAST
No
RSP5_YEAST
No
RT23_YEAST
No
RT27_YEAST
No
SA155_YEAST
No
SEN2_YEAST
No
SHC1_YEAST
No
SIP1_YEAST
No
SLF1_YEAST
No
SNA3_YEAST
No
SPC29_YEAST
No
SPC97_YEAST
No
SPO75_YEAST
No
SUR1_YEAST
No
SVL3_YEAST
No
SYF1_YEAST
No
TAT1_YEAST
No
TDA5_YEAST
No
TECR_YEAST
No
TGL3_YEAST
No
TIM22_YEAST
No
TLG2_YEAST
No
UBP4_YEAST
No
UBP7_YEAST
No
UBR2_YEAST
No
URM1_YEAST
No
VMR1_YEAST
No
VPS73_YEAST
No
VTC4_YEAST
No
YAG4_YEAST
No
YB09A_YEAST
No
YCR2_YEAST
No
YD042_YEAST
No
YD056_YEAST
No
YD172_YEAST
No
YD271_YEAST
No
YEQ9_YEAST
No
YFB2_YEAST
No
YFT2_YEAST
No
YG2Z_YEAST
No
YHE4_YEAST
No
YJI6_YEAST
No
YJP2_YEAST
No
YK12_YEAST
No
YKR7_YEAST
No
YL054_YEAST
No
YL112_YEAST
No
YM87_YEAST
No
YMN1_YEAST
No
YO059_YEAST
No
YO389_YEAST
No
YOR1_YEAST
No
YP277_YEAST
No
ZRT3_YEAST
No
Publications Associated
PMID
Article Title
8091229
Complete nucleotide sequence of Saccharomyces cerevisiae chromosome VIII.
12391157
Saccharomyces cerevisiae Bzz1p is implicated with type I myosins in actin patch polarization and is able to recruit actin-polymerizing machinery in vitro.
14562106
Global analysis of protein expression in yeast.
16231105
The WASP/Las17p-interacting protein Bzz1p functions with Myo5p in an early stage of endocytosis.
17322287
Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
18407956
A multidimensional chromatography technology for in-depth phosphoproteome analysis.
19779198
Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
24374639
The reference genome sequence of Saccharomyces cerevisiae: Then and now.
OMIM Diseases Associated
No results found.
Protein Domains Associated
Domain Name
Domain ID
Source
FCH_dom
IPR001060
InterPro
SH3_domain
IPR001452
InterPro
AH/BAR_dom_sf
IPR027267
InterPro
F_BAR
IPR031160
InterPro
SH3-like_dom_sf
IPR036028
InterPro
SH3_1
PF00018
Pfam
FCH
PF00611
Pfam
SH3_9
PF14604
Pfam
SH3
PS50002
PROSITE
F_BAR
PS51741
PROSITE
S48956
S48956
PIR
FCH
SM00055
SMART
SH3
SM00326
SMART
SSF103657
SSF103657
SUPFAM
SSF50044
SSF50044
SUPFAM