|Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway.
|Expression of constitutively active alpha-PAK reveals effects of the kinase on actin and focal complexes.
|Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells.
|A conserved negative regulatory region in alphaPAK: inhibition of PAK kinases reveals their morphological roles downstream of Cdc42 and Rac1.
|Differential effects of PAK1-activating mutations reveal activity-dependent and -independent effects on cytoskeletal regulation.
|Identification of Grb4/Nckbeta, a src homology 2 and 3 domain-containing adapter protein having similar binding and biological properties to Nck.
|Identification of a central phosphorylation site in p21-activated kinase regulating autoinhibition and kinase activity.
|Structure of PAK1 in an autoinhibited conformation reveals a multistage activation switch.
|p21-activated kinase (PAK1) is phosphorylated and activated by 3-phosphoinositide-dependent kinase-1 (PDK1).
|Interaction between active Pak1 and Raf-1 is necessary for phosphorylation and activation of Raf-1.
|Pak1 kinase homodimers are autoinhibited in trans and dissociated upon activation by Cdc42 and Rac1.
|The C-terminal kinase domain of the p34cdc2-related PITSLRE protein kinase (p110C) associates with p21-activated kinase 1 and inhibits its activity during anoikis.
|PAK1 phosphorylation of MEK1 regulates fibronectin-stimulated MAPK activation.
|Akt phosphorylation of serine 21 on Pak1 modulates Nck binding and cell migration.
|The Down syndrome cell adhesion molecule (DSCAM) interacts with and activates Pak.
|The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
|Integrin engagement differentially modulates epithelial cell motility by RhoA/ROCK and PAK1.
|p21-activated kinase 1 regulates microtubule dynamics by phosphorylating tubulin cofactor B.
|Pak1 phosphorylation of snail, a master regulator of epithelial-to-mesenchyme transition, modulates snail's subcellular localization and functions.
|The active conformation of the PAK1 kinase domain.
|Essential role of CIB1 in regulating PAK1 activation and cell migration.
|Structural analysis of the SH3 domain of beta-PIX and its interaction with alpha-p21 activated kinase (PAK).
|CRIPak, a novel endogenous Pak1 inhibitor.
|Human chromosome 11 DNA sequence and analysis including novel gene identification.
|A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
|JAK2 tyrosine kinase phosphorylates PAK1 and regulates PAK1 activity and functions.
|Identification of phosphorylation sites in betaPIX and PAK1.
|Affixin activates Rac1 via betaPIX in C2C12 myoblast.
|A quantitative atlas of mitotic phosphorylation.
|Scrib regulates PAK activity during the cell migration process.
|Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.
|Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
|Initial characterization of the human central proteome.
|System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.
|Structural insights into the autoactivation mechanism of p21-activated protein kinase.
|Synapses of amphids defective (SAD-A) kinase promotes glucose-stimulated insulin secretion through activation of p21-activated kinase (PAK1) in pancreatic beta-Cells.
|N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
|Toward a comprehensive characterization of a human cancer cell phosphoproteome.
|A novel splice variant of calcium and integrin-binding protein 1 mediates protein kinase D2-stimulated tumour growth by regulating angiogenesis.
|Beta-arrestin-dependent activation of the cofilin pathway is required for the scavenging activity of the atypical chemokine receptor D6.
|An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
|PAK1 regulates RUFY3-mediated gastric cancer cell migration and invasion.
|Glucose-regulated protein 78 (GRP78) binds directly to PIP3 phosphatase SKIP and determines its localization.