Protein: P60411

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P60411 (Uniprot) KR109_HUMAN KRTAP10-9 Keratin-associated protein 10-9 human No
Uniprot: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins. more..
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0043170 macromolecule metabolic process 114 GO:0033036 macromolecule localization 517 2.48e-08 1.95e-27
GO:0044260 cellular macromolecule metabolic process 127, 340 GO:0033036 macromolecule localization 517 4.56e-06 3.25e-28
GO:0009059 macromolecule biosynthetic process 461 GO:0033036 macromolecule localization 517 2.32e-08 6.09e-30
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
62 GO:0034645 cellular macromolecule biosynthetic process
62 GO:0090304 nucleic acid metabolic process
62 GO:1901362 organic cyclic compound biosynthetic process
62 GO:0060255 regulation of macromolecule metabolic process
80 GO:0051252 regulation of RNA metabolic process
80 GO:0010468 regulation of gene expression
114 GO:0019538 protein metabolic process
127 GO:0016070 RNA metabolic process
127 GO:0010467 gene expression
160 GO:0006355 regulation of transcription, DNA-templated
340 GO:0016070 RNA metabolic process
340 GO:0010467 gene expression
340 GO:0060255 regulation of macromolecule metabolic process
461 GO:0034645 cellular macromolecule biosynthetic process
461 GO:0090304 nucleic acid metabolic process
461 GO:0034654 nucleobase-containing compound biosynthetic process
517 GO:0008104 protein localization
517 GO:0019538 protein metabolic process
646 GO:0060255 regulation of macromolecule metabolic process
646 GO:0006351 transcription, DNA-templated
718 GO:0016070 RNA metabolic process
718 GO:0010467 gene expression
874 GO:0034645 cellular macromolecule biosynthetic process
874 GO:0010646 regulation of cell communication
874 GO:0023051 regulation of signaling
874 GO:0007165 signal transduction
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
62 GO:0005829 cytosol
62 GO:0005634 nucleus
80 GO:0005634 nucleus
127 GO:0005634 nucleus
160 GO:0005634 nucleus
340 GO:0005634 nucleus
461 GO:0043232 intracellular non-membrane-bounded organelle
461 GO:0005634 nucleus
517 GO:0005829 cytosol
517 GO:0012505 endomembrane system
517 GO:0031982 vesicle
562 GO:0005829 cytosol
562 GO:0043232 intracellular non-membrane-bounded organelle
567 GO:0005634 nucleus
646 GO:0005856 cytoskeleton
646 GO:0005634 nucleus
718 GO:0043232 intracellular non-membrane-bounded organelle
718 GO:0005634 nucleus
755 GO:0005829 cytosol
874 GO:0043232 intracellular non-membrane-bounded organelle
874 GO:0005634 nucleus
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0031424 keratinization TAS
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0005829 cytosol TAS
GO:0045095 keratin filament IEA
No pairs of PrOnto dissimilar CC GO terms found.
Interactor Also a MoonDB EMF protein
PRP31_HUMAN No
CRTP1_HUMAN No
KRA59_HUMAN No
KR123_HUMAN No
KR108_HUMAN No
KRA92_HUMAN No
A0A024R4S4_HUMAN No
KR107_HUMAN No
3BHS7_HUMAN No
6PGL_HUMAN No
A8KA13_HUMAN No
AAKB2_HUMAN No
AAPK2_HUMAN No
ACHG_HUMAN No
AES_HUMAN Yes: Q08117 (MoonDB)
AL3B1_HUMAN No
ANFB_HUMAN No
ARFG1_HUMAN No
AT7L1_HUMAN No
ATL4_HUMAN No
AVPI1_HUMAN No
AXIN2_HUMAN No
BCL6B_HUMAN No
BMP7_HUMAN No
CATIP_HUMAN No
CBX2_HUMAN No
CCD26_HUMAN No
CDKL3_HUMAN No
CE060_HUMAN No
CGB2_HUMAN No
CHIC2_HUMAN No
CHRD_HUMAN No
CJ062_HUMAN No
CK087_HUMAN No
CKS1_HUMAN No
CLK4_HUMAN No
CLM9_HUMAN No
CNNM3_HUMAN No
CP059_HUMAN No
CRCT1_HUMAN No
CREB5_HUMAN No
CS057_HUMAN No
CST9L_HUMAN No
CTSR1_HUMAN No
CXL16_HUMAN No
DHRS1_HUMAN No
DHX57_HUMAN No
DMRT3_HUMAN No
DOCK2_HUMAN No
EZH2_HUMAN No
F124B_HUMAN No
F161A_HUMAN No
FA76B_HUMAN No
FAM74_HUMAN No
FBXW5_HUMAN No
GATA2_HUMAN No
GBRL1_HUMAN No
GBRL2_HUMAN Yes: P60520 (MoonDB)
GLCNE_HUMAN No
GLP1R_HUMAN No
GLRX3_HUMAN No
GPT2L_HUMAN No
GSTP1_HUMAN No
GUCD1_HUMAN No
HBAZ_HUMAN No
HBG1_HUMAN No
HCK_HUMAN No
HES6_HUMAN No
HPCL1_HUMAN No
HSBP1_HUMAN No
HXA1_HUMAN No
HXB9_HUMAN No
HXC8_HUMAN No
IF4E2_HUMAN No
IGSF8_HUMAN No
IQUB_HUMAN No
ITB4_HUMAN No
ITB5_HUMAN No
K1C20_HUMAN No
KAT5_HUMAN No
KCC2B_HUMAN No
KIF9_HUMAN No
KLH38_HUMAN No
KR103_HUMAN No
KR121_HUMAN No
KR261_HUMAN No
KR411_HUMAN No
KR412_HUMAN No
KR511_HUMAN No
KRA11_HUMAN No
KRA42_HUMAN No
KRA56_HUMAN No
KRA93_HUMAN No
KRA94_HUMAN No
KRT83_HUMAN No
LCE1A_HUMAN No
LCE1B_HUMAN No
LCE1D_HUMAN No
LCE1E_HUMAN No
LCE1F_HUMAN No
LCE2A_HUMAN No
LCE2B_HUMAN No
LCE2C_HUMAN No
LCE2D_HUMAN No
LCE3A_HUMAN No
LCE3B_HUMAN No
LCE3C_HUMAN No
LCE3D_HUMAN No
LCE3E_HUMAN No
LCE4A_HUMAN No
LCE5A_HUMAN No
LUZP4_HUMAN No
MABP1_HUMAN No
MAZ_HUMAN No
MB213_HUMAN No
MCSP_HUMAN No
MED30_HUMAN No
MEOX2_HUMAN Yes: P50222 (MoonDB)
MOBP_HUMAN No
MT1DP_HUMAN No
MXI1_HUMAN No
MYPOP_HUMAN No
NECT3_HUMAN No
NKD1_HUMAN No
NNRD_HUMAN No
NPBW2_HUMAN No
NPDC1_HUMAN No
NR1D2_HUMAN No
NT2NL_HUMAN No
NUFP2_HUMAN No
OTX1_HUMAN No
PCSK5_HUMAN No
PDE9A_HUMAN No
PE2R3_HUMAN No
PGAP2_HUMAN No
PGFRB_HUMAN No
PIGS_HUMAN No
PIN1_HUMAN No
PLS1_HUMAN No
PPBI_HUMAN No
PVR_HUMAN No
Q49AR9_HUMAN No
Q6NSM0_HUMAN No
Q9NWL9_HUMAN No
RAB7A_HUMAN No
RASD1_HUMAN No
RHNO1_HUMAN No
RSPO2_HUMAN No
RYDEN_HUMAN No
S23A1_HUMAN No
S6A20_HUMAN No
SACA9_HUMAN No
SCNM1_HUMAN No
SCRB1_HUMAN No
SEM3B_HUMAN No
SHIP1_HUMAN No
SMCE1_HUMAN No
SPAT8_HUMAN No
SPG7_HUMAN No
SPTA3_HUMAN No
SPY1_HUMAN No
SPY2_HUMAN No
STK16_HUMAN No
STP2_HUMAN No
SYFM_HUMAN No
TBC16_HUMAN No
TBC23_HUMAN No
TGON2_HUMAN No
THA10_HUMAN No
TNF6B_HUMAN No
TRI41_HUMAN Yes: Q8WV44 (MoonDB)
TRI42_HUMAN No
TXND5_HUMAN No
TYMOS_HUMAN No
TYRO3_HUMAN No
TYY1_HUMAN No
U633C_HUMAN No
UTP23_HUMAN No
VGLL3_HUMAN No
WIT1_HUMAN No
WNT11_HUMAN No
XCL2_HUMAN No
YIPF3_HUMAN No
Z286A_HUMAN No
ZBT24_HUMAN No
ZBT38_HUMAN No
ZBTB9_HUMAN No
ZFY26_HUMAN No
ZN124_HUMAN No
ZN155_HUMAN No
ZN165_HUMAN No
ZN264_HUMAN No
ZN317_HUMAN No
ZN319_HUMAN No
ZN417_HUMAN Yes: Q8TAU3 (MoonDB)
ZN433_HUMAN No
ZN439_HUMAN No
ZN440_HUMAN No
ZN473_HUMAN No
ZN497_HUMAN No
ZN524_HUMAN No
ZN564_HUMAN No
ZN572_HUMAN No
ZN578_HUMAN No
ZN581_HUMAN No
ZN587_HUMAN No
ZN599_HUMAN No
ZN625_HUMAN No
ZN646_HUMAN No
ZN696_HUMAN No
ZN697_HUMAN No
ZN699_HUMAN No
ZN764_HUMAN No
ZN774_HUMAN No
ZN777_HUMAN No
ZN792_HUMAN No
ZN837_HUMAN No
ZN844_HUMAN No
ZNF20_HUMAN No
ZNF80_HUMAN No
ZSC21_HUMAN No
ZSC26_HUMAN No
PMID Article Title
10830953 The DNA sequence of human chromosome 21.
14962103 Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.
15028290 A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.
15489334 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
No results found.
Domain Name Domain ID Source
KAP IPR002494 InterPro
Keratin_B2_2 PF13885 Pfam
PTHR23262 PTHR23262 PANTHER