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A Database of Extreme Multifunctional and Moonlighting Proteins
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About
Protein: P57086
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
P57086 (Uniprot)
SCND1_HUMAN
SCAND1
SCAN domain-containing protein 1
human
No
Protein Function
Uniprot:
May regulate transcriptional activity.
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0006139
nucleobase-containing compound metabolic process
132
GO:0007165
signal transduction
355
1.10e-111
5.07e-25
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
29
GO:0060255
regulation of macromolecule metabolic process
29
GO:0007165
signal transduction
62
GO:0034645
cellular macromolecule biosynthetic process
62
GO:0090304
nucleic acid metabolic process
62
GO:1901362
organic cyclic compound biosynthetic process
62
GO:0060255
regulation of macromolecule metabolic process
132
GO:0090304
nucleic acid metabolic process
132
GO:0060255
regulation of macromolecule metabolic process
355
GO:0007166
cell surface receptor signaling pathway
355
GO:0006464
cellular protein modification process
355
GO:0035556
intracellular signal transduction
355
GO:0016310
phosphorylation
355
GO:0010647
positive regulation of cell communication
355
GO:0048584
positive regulation of response to stimulus
355
GO:0023056
positive regulation of signaling
355
GO:0060255
regulation of macromolecule metabolic process
355
GO:0009966
regulation of signal transduction
401
GO:0034645
cellular macromolecule biosynthetic process
401
GO:0060255
regulation of macromolecule metabolic process
479
GO:0016070
RNA metabolic process
479
GO:0034645
cellular macromolecule biosynthetic process
479
GO:0044271
cellular nitrogen compound biosynthetic process
479
GO:0044267
cellular protein metabolic process
479
GO:0010468
regulation of gene expression
479
GO:0007165
signal transduction
511
GO:0010467
gene expression
511
GO:0051252
regulation of RNA metabolic process
581
GO:0031326
regulation of cellular biosynthetic process
581
GO:0060255
regulation of macromolecule metabolic process
581
GO:0019219
regulation of nucleobase-containing compound metabolic process
581
GO:0006351
transcription, DNA-templated
657
GO:0006355
regulation of transcription, DNA-templated
657
GO:0007165
signal transduction
688
GO:0006355
regulation of transcription, DNA-templated
688
GO:0007165
signal transduction
782
GO:0006355
regulation of transcription, DNA-templated
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
29
GO:0005634
nucleus
62
GO:0005829
cytosol
62
GO:0005634
nucleus
132
GO:0005634
nucleus
135
GO:0005634
nucleus
231
GO:0005634
nucleus
355
GO:0044459
plasma membrane part
401
GO:0005634
nucleus
479
GO:0070013
intracellular organelle lumen
479
GO:0044428
nuclear part
511
GO:0005634
nucleus
581
GO:0005634
nucleus
657
GO:0005634
nucleus
688
GO:0005634
nucleus
782
GO:0005634
nucleus
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0006355
regulation of transcription, DNA-templated
IEA
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005634
nucleus
IDA
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
PICK1_HUMAN
Yes:
Q9NRD5 (MoonDB)
PNMA1_HUMAN
No
PGBD1_HUMAN
No
GG6L9_HUMAN
No
TRIP6_HUMAN
No
K1C40_HUMAN
No
OBF1_HUMAN
No
ZN165_HUMAN
No
APH1A_HUMAN
No
ATRAP_HUMAN
No
CACO2_HUMAN
No
CCD51_HUMAN
No
DG2L6_HUMAN
No
GORS2_HUMAN
No
LHX4_HUMAN
No
MK03_HUMAN
Yes:
P27361 (MoonDB)
MK08_HUMAN
No
MZF1_HUMAN
No
NDUB5_HUMAN
No
NFE2_HUMAN
No
RER1_HUMAN
No
RN186_HUMAN
No
RPRM_HUMAN
No
SHSA5_HUMAN
No
SPHAR_HUMAN
No
TM207_HUMAN
No
TM239_HUMAN
No
TMM95_HUMAN
No
TV23A_HUMAN
No
ZKSC3_HUMAN
No
ZKSC4_HUMAN
No
ZKSC7_HUMAN
No
ZN174_HUMAN
No
ZN213_HUMAN
No
ZN263_HUMAN
No
ZN394_HUMAN
No
ZN396_HUMAN
No
ZN397_HUMAN
No
ZN446_HUMAN
No
ZN449_HUMAN
No
ZN483_HUMAN
No
ZN496_HUMAN
No
ZNF24_HUMAN
No
ZSC12_HUMAN
No
ZSC18_HUMAN
No
ZSC20_HUMAN
No
ZSC22_HUMAN
No
ZSC23_HUMAN
No
ZSC32_HUMAN
No
ZSC9_HUMAN
No
Publications Associated
PMID
Article Title
10747874
The SCAN domain mediates selective oligomerization.
11780052
The DNA sequence and comparative analysis of human chromosome 20.
15489334
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
OMIM Diseases Associated
No results found.
Protein Domains Associated
Domain Name
Domain ID
Source
SCAN_dom
IPR003309
InterPro
Retrov_capsid_C
IPR008916
InterPro
SCAN
PF02023
Pfam
SCAN_BOX
PS50804
PROSITE
SCAN
SM00431
SMART
SSF47353
SSF47353
SUPFAM
SCAN
cd07936
CDD