Protein: P32856 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
P32856 (Uniprot)	STX2_HUMAN	STX2	Syntaxin-2	human	Yes

Protein Function

Uniprot: Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

Function 1: Epithelial morphogen signalling, binds alpha-intergrins. Condition: extracellular localisation.

Function 2: Vesicle fusion. Condition: intracellular localisation.

Publications (PMID): 18354082, 17535848

MoonDB Network Modules

Biological Processes

No results found.

Cellular Components

Showing 1 to 8 of 8 entries

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Module ID (MoonGO)	GO ID (CC)	GO Name
65	GO:0012505	endomembrane system
65	GO:0016021	integral component of membrane
85	GO:0016021	integral component of membrane
389	GO:0012505	endomembrane system
389	GO:0016021	integral component of membrane
633	GO:0005829	cytosol
633	GO:0031982	vesicle
858	GO:0005634	nucleus

Protein GO Annotations

Biological Processes

Showing 1 to 10 of 12 entries

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0006886	intracellular protein transport	IBA
GO:0007165	signal transduction	TAS
GO:0007340	acrosome reaction	ISS
GO:0007398	ectoderm development	TAS
GO:0009887	animal organ morphogenesis	TAS
GO:0030154	cell differentiation	IEA
GO:0030193	regulation of blood coagulation	IMP
GO:0031629	synaptic vesicle fusion to presynaptic active zone membrane	IBA
GO:0033194	response to hydroperoxide	IDA
GO:0048278	vesicle docking	IBA

Cellular Components

Showing 1 to 9 of 9 entries

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005615	extracellular space	IDA
GO:0005886	plasma membrane	IDA
GO:0008021	synaptic vesicle	IBA
GO:0016021	integral component of membrane	IBA
GO:0016323	basolateral plasma membrane	IDA
GO:0030027	lamellipodium	IDA
GO:0031201	SNARE complex	IBA
GO:0043231	intracellular membrane-bounded organelle	TAS
GO:0070062	extracellular exosome	IDA

Showing 1 to 3 of 3 entries

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GO ID 1	Component 1	GO ID 2	Component 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0005615	extracellular space	GO:0043231	intracellular membrane-bounded organelle	5.04e-30	2.07e-03
GO:0005886	plasma membrane	GO:0043231	intracellular membrane-bounded organelle	0.00e+00	3.79e-47
GO:0016021	integral component of membrane	GO:0043231	intracellular membrane-bounded organelle	3.85e-142	2.23e-72

All Protein Interactions

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Publications Associated

Showing 1 to 3 of 3 entries

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PMID	Article Title
8466509	Molecular cloning of human epimorphin: identification of isoforms and their unique properties.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
16541075	The finished DNA sequence of human chromosome 12.

OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 10 of 14 entries

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