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A Database of Extreme Multifunctional and Moonlighting Proteins
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About
Protein: O17670
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
O17670 (Uniprot)
O17670_CAEEL
eya-1
Eyes absent homolog
worm
No
Protein Function
No associated function.
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0019219
regulation of nucleobase-containing compound metabolic process
2308
GO:0019538
protein metabolic process
2333
3.12e-03
1.26e-07
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
2158
GO:0006355
regulation of transcription, DNA-templated
2187
GO:0016070
RNA metabolic process
2187
GO:0010467
gene expression
2200
GO:0006355
regulation of transcription, DNA-templated
2247
GO:0006355
regulation of transcription, DNA-templated
2307
GO:0006355
regulation of transcription, DNA-templated
2308
GO:0051252
regulation of RNA metabolic process
2308
GO:0010468
regulation of gene expression
2311
GO:0006355
regulation of transcription, DNA-templated
2333
GO:0044267
cellular protein metabolic process
2333
GO:0006355
regulation of transcription, DNA-templated
2333
GO:0007165
signal transduction
2343
GO:0006355
regulation of transcription, DNA-templated
2346
GO:0016070
RNA metabolic process
2346
GO:0010467
gene expression
2372
GO:0006355
regulation of transcription, DNA-templated
2382
GO:0044271
cellular nitrogen compound biosynthetic process
2382
GO:0010467
gene expression
2382
GO:0006139
nucleobase-containing compound metabolic process
2386
GO:0006355
regulation of transcription, DNA-templated
2407
GO:0006355
regulation of transcription, DNA-templated
2408
GO:0006355
regulation of transcription, DNA-templated
2429
GO:0006355
regulation of transcription, DNA-templated
2446
GO:0060255
regulation of macromolecule metabolic process
2499
GO:0006355
regulation of transcription, DNA-templated
2509
GO:0006357
regulation of transcription from RNA polymerase II promoter
2515
GO:0016070
RNA metabolic process
2545
GO:0044271
cellular nitrogen compound biosynthetic process
2545
GO:0051252
regulation of RNA metabolic process
2545
GO:2000112
regulation of cellular macromolecule biosynthetic process
2545
GO:0010468
regulation of gene expression
2549
GO:0006355
regulation of transcription, DNA-templated
2557
GO:0016070
RNA metabolic process
2557
GO:0010467
gene expression
2557
GO:0060255
regulation of macromolecule metabolic process
2608
GO:0006355
regulation of transcription, DNA-templated
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
2158
GO:0005634
nucleus
2187
GO:0005634
nucleus
2200
GO:0005634
nucleus
2247
GO:0005634
nucleus
2307
GO:0005634
nucleus
2308
GO:0005634
nucleus
2311
GO:0005634
nucleus
2333
GO:0005634
nucleus
2343
GO:0005634
nucleus
2372
GO:0005634
nucleus
2386
GO:0005634
nucleus
2407
GO:0005634
nucleus
2408
GO:0005634
nucleus
2429
GO:0005634
nucleus
2489
GO:0005634
nucleus
2499
GO:0005634
nucleus
2509
GO:0005634
nucleus
2515
GO:0005634
nucleus
2545
GO:0005634
nucleus
2549
GO:0005634
nucleus
2557
GO:0005634
nucleus
2608
GO:0005634
nucleus
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0002119
nematode larval development
IMP
GO:0006355
regulation of transcription, DNA-templated
IEA
GO:0007501
mesodermal cell fate specification
IMP
GO:0016576
histone dephosphorylation
IBA
GO:0018991
oviposition
IMP
GO:0035335
peptidyl-tyrosine dephosphorylation
IEA
GO:0040011
locomotion
IMP
GO:0043066
negative regulation of apoptotic process
IMP
GO:0045739
positive regulation of DNA repair
IBA
GO:0048598
embryonic morphogenesis
IMP
GO:0048729
tissue morphogenesis
IMP
GO:2001240
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand
IBA
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005634
nucleus
IDA
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
G5EGG0_CAEEL
No
TBX9_CAEEL
Yes:
Q22289 (MoonDB)
YTE4_CAEEL
No
ABL1_CAEEL
No
SIN3_CAEEL
No
A0A131MBF9_CAEEL
No
A3RMS1_CAEEL
No
ASD2_CAEEL
No
B5U8M3_CAEEL
No
CLP1_CAEEL
No
CSK2B_CAEEL
No
D3YT69_CAEEL
No
DYC1_CAEEL
No
EGL13_CAEEL
No
EGL27_CAEEL
No
ELT7_CAEEL
No
FOS1_CAEEL
No
FOX1_CAEEL
No
FOZI1_CAEEL
No
G5EBS8_CAEEL
No
G5EBV4_CAEEL
No
G5EC57_CAEEL
No
G5ECJ4_CAEEL
No
G5ED66_CAEEL
No
G5EDS1_CAEEL
No
G5EDU4_CAEEL
No
G5EEG5_CAEEL
No
G5EEM0_CAEEL
No
G5EEW2_CAEEL
No
G5EEW7_CAEEL
No
G5EF74_CAEEL
No
G5EF87_CAEEL
No
G5EFF4_CAEEL
No
G5EFY6_CAEEL
No
GLD3_CAEEL
No
GUAA_CAEEL
No
H2KZ64_CAEEL
No
H2KZ78_CAEEL
No
H2KZI6_CAEEL
No
H2KZU4_CAEEL
No
H2L008_CAEEL
No
H2L031_CAEEL
No
H2L0B3_CAEEL
No
H2L0D2_CAEEL
No
H2L0D3_CAEEL
No
H2L0M8_CAEEL
No
H8ESF3_CAEEL
No
HM30_CAEEL
No
HM33_CAEEL
No
HM34_CAEEL
No
LAG3_CAEEL
No
MAB5_CAEEL
No
MED8_CAEEL
No
MOE2_CAEEL
No
MOE3_CAEEL
No
NH111_CAEEL
No
NHR13_CAEEL
No
NHR22_CAEEL
No
NHR49_CAEEL
No
NHR67_CAEEL
No
NU301_CAEEL
No
O02289_CAEEL
No
O16213_CAEEL
No
O17894_CAEEL
No
O44447_CAEEL
No
O44505_CAEEL
No
O45784_CAEEL
No
O61708_CAEEL
No
O62020_CAEEL
No
O62159_CAEEL
No
O62259_CAEEL
No
ODD2_CAEEL
No
P91820_CAEEL
No
PHA4_CAEEL
No
PICAL_CAEEL
No
POP1_CAEEL
No
Q10923_CAEEL
No
Q10924_CAEEL
No
Q17508_CAEEL
No
Q17979_CAEEL
No
Q18043_CAEEL
No
Q18171_CAEEL
No
Q18241_CAEEL
No
Q18299_CAEEL
No
Q18477_CAEEL
No
Q18694_CAEEL
No
Q18937_CAEEL
No
Q18999_CAEEL
No
Q19007_CAEEL
No
Q19418_CAEEL
No
Q19610_CAEEL
No
Q19760_CAEEL
No
Q20677_CAEEL
No
Q20956_CAEEL
No
Q20968_CAEEL
No
Q21021_CAEEL
No
Q21126_CAEEL
No
Q21127_CAEEL
No
Q21361_CAEEL
No
Q21372_CAEEL
No
Q22178_CAEEL
No
Q22805_CAEEL
No
Q22826_CAEEL
No
Q27420_CAEEL
No
Q2EEM5_CAEEL
No
Q65XX7_CAEEL
No
Q65ZG6_CAEEL
No
Q86DA8_CAEEL
No
Q86G90_CAEEL
No
Q8MQ25_CAEEL
No
Q8T3E6_CAEEL
No
Q93616_CAEEL
No
Q93619_CAEEL
No
Q95X37_CAEEL
No
Q9BIC1_CAEEL
No
Q9GUC8_CAEEL
No
Q9GYQ9_CAEEL
No
Q9N2W3_CAEEL
No
Q9N3A3_CAEEL
No
Q9N410_CAEEL
No
Q9N4L9_CAEEL
No
Q9N4P3_CAEEL
No
Q9N582_CAEEL
No
Q9NAE4_CAEEL
No
Q9NAE9_CAEEL
No
Q9TXN8_CAEEL
No
Q9U1R1_CAEEL
No
Q9U1S2_CAEEL
No
Q9U1W1_CAEEL
No
Q9U226_CAEEL
No
Q9U289_CAEEL
No
Q9U3S8_CAEEL
No
Q9XUK2_CAEEL
No
Q9XV36_CAEEL
No
Q9XVN4_CAEEL
No
Q9XXU2_CAEEL
No
RLE1_CAEEL
No
SMA4_CAEEL
No
TAF1_CAEEL
No
TBX39_CAEEL
No
UNC30_CAEEL
No
UNC37_CAEEL
No
V6CLE9_CAEEL
No
W6RTE4_CAEEL
No
WBS14_CAEEL
No
X5LV54_CAEEL
No
YL18_CAEEL
No
YL87_CAEEL
No
YR01_CAEEL
No
Publications Associated
PMID
Article Title
9851916
Genome sequence of the nematode C. elegans: a platform for investigating biology.
OMIM Diseases Associated
No results found.
Protein Domains Associated
Domain Name
Domain ID
Source
EYA_dom
IPR006545
InterPro
EYA_fam
IPR028472
InterPro
PTHR10190
PTHR10190
PANTHER
T20047
T20047
PIR
HAD_Eya
cd02601
CDD