Protein: Q06449

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
Q06449 (Uniprot) PIN3_YEAST PIN3 [PSI+] inducibility protein 3 yeast No
Uniprot: Overproduction promotes the de novo induction of the [PSI+] prion form of SUP35. The prion-inducing effect depends on the association with the actin cytoskeleton. Also implicated in prion maintenance during heat stress.
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0043170 macromolecule metabolic process 1073 GO:0097435 supramolecular fiber organization 1177 4.36e-08 1.57e-47
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
1073 GO:0010467 gene expression
1177 GO:0007015 actin filament organization
1177 GO:0022607 cellular component assembly
1177 GO:0044087 regulation of cellular component biogenesis
1177 GO:0033043 regulation of organelle organization
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
884 GO:0043232 intracellular non-membrane-bounded organelle
984 GO:0012505 endomembrane system
996 GO:0005634 nucleus
1000 GO:0005634 nucleus
1177 GO:0005856 cytoskeleton
1177 GO:0005634 nucleus
1199 GO:0005634 nucleus
1216 GO:0005634 nucleus
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation IPI
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0005634 nucleus IEA
GO:0005737 cytoplasm IDA
GO:0030479 actin cortical patch IDA
GO ID 1 Component 1 GO ID 2 Component 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0005634 nucleus GO:0005737 cytoplasm 5.14e-51 7.30e-86
PMID Article Title
9169875 The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
10512884 The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.
11511345 Prions affect the appearance of other prions: the story of [PIN(+)].
12872131 A proteomics approach to understanding protein ubiquitination.
14562095 Global analysis of protein localization in budding yeast.
14562106 Global analysis of protein expression in yeast.
17322287 Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
19779198 Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
21777813 Prion induction by the short-lived, stress-induced protein Lsb2 is regulated by ubiquitination and association with the actin cytoskeleton.
22000681 Yeast Rsp5 ubiquitin ligase affects the actin cytoskeleton in vivo and in vitro.
22106047 Sites of ubiquitin attachment in Saccharomyces cerevisiae.
22814378 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
SH3_domain IPR001452 InterPro
SH3-like_dom_sf IPR036028 InterPro
SH3_1 PF00018 Pfam
SH3DOMAIN PR00452 PRINTS
SH3 PS50002 PROSITE
S61138 S61138 PIR
SH3 SM00326 SMART
SSF50044 SSF50044 SUPFAM