Protein: P46527

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P46527 (Uniprot) CDN1B_HUMAN CDKN1B Cyclin-dependent kinase inhibitor 1B human No
Uniprot: Important regulator of cell cycle progression. Inhibits the kinase activity of CDK2 bound to cyclin A, but has little inhibitory activity on CDK2 bound to SPDYA (PubMed:28666995). Involved in G1 arrest. Potent inhibitor of cyclin E- and cyclin A-CDK2 complexes. Forms a complex with cyclin type D-CDK4 complexes an more..