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A Database of Extreme Multifunctional and Moonlighting Proteins
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About
Protein: P24278
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
P24278 (Uniprot)
ZBT25_HUMAN
ZBTB25
Zinc finger and BTB domain-containing protein 25
human
No
Protein Function
Uniprot:
May be involved in transcriptional regulation.
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0044260
cellular macromolecule metabolic process
364
GO:0033036
macromolecule localization
517
4.56e-06
3.25e-28
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
364
GO:0016070
RNA metabolic process
364
GO:0010468
regulation of gene expression
517
GO:0008104
protein localization
517
GO:0019538
protein metabolic process
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
84
GO:0005634
nucleus
364
GO:0005634
nucleus
517
GO:0005829
cytosol
517
GO:0012505
endomembrane system
517
GO:0031982
vesicle
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0006351
transcription, DNA-templated
IEA
GO:0006355
regulation of transcription, DNA-templated
IEA
GO:0010467
gene expression
IEP
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005654
nucleoplasm
IDA
GO:0005737
cytoplasm
IDA
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
CRTP1_HUMAN
No
KR108_HUMAN
No
MDFI_HUMAN
No
VINEX_HUMAN
No
COIL_HUMAN
No
TRAF2_HUMAN
No
FHL2_HUMAN
No
MTNB_HUMAN
No
TNIP1_HUMAN
No
PNMA5_HUMAN
No
MK09_HUMAN
No
DDIT3_HUMAN
No
LZTS2_HUMAN
No
KCTD9_HUMAN
No
HSBP1_HUMAN
No
CP2J2_HUMAN
No
EFC4A_HUMAN
No
FCG3A_HUMAN
No
HCLS1_HUMAN
No
KCTD1_HUMAN
No
KR171_HUMAN
No
KXDL1_HUMAN
No
PHS_HUMAN
Yes:
P61457 (MoonDB)
SPS1_HUMAN
No
SSX3_HUMAN
No
TBCD5_HUMAN
No
TERA_HUMAN
Yes:
P55072 (MoonDB)
TRAF6_HUMAN
Yes:
Q9Y4K3 (MoonDB)
TSSK3_HUMAN
No
VMAC_HUMAN
No
ZBTB1_HUMAN
No
ZBTB2_HUMAN
No
Publications Associated
PMID
Article Title
2027750
The KUP gene, located on human chromosome 14, encodes a protein with two distant zinc fingers.
14702039
Complete sequencing and characterization of 21,243 full-length human cDNAs.
15489334
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
25755297
System-wide analysis of SUMOylation dynamics in response to replication stress reveals novel small ubiquitin-like modified target proteins and acceptor lysines relevant for genome stability.
28112733
Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
OMIM Diseases Associated
No results found.
Protein Domains Associated
Domain Name
Domain ID
Source
BTB/POZ_dom
IPR000210
InterPro
SKP1/BTB/POZ_sf
IPR011333
InterPro
Znf_RING/FYVE/PHD
IPR013083
InterPro
Znf_C2H2_type
IPR013087
InterPro
Znf_C2H2_sf
IPR036236
InterPro
BTB
PF00651
Pfam
ZINC_FINGER_C2H2_1
PS00028
PROSITE
BTB
PS50097
PROSITE
ZINC_FINGER_C2H2_2
PS50157
PROSITE
S15647
S15647
PIR
BTB
SM00225
SMART
ZnF_C2H2
SM00355
SMART
SSF54695
SSF54695
SUPFAM
SSF57667
SSF57667
SUPFAM