Protein: P00330 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
P00330 (Uniprot)	ADH1_YEAST	ADH1	Alcohol dehydrogenase 1	yeast	Yes

Protein Function

Uniprot: This isozyme preferentially catalyzes the conversion of primary unbranched alcohols to their corresponding aldehydes. Also also shows activity toward secondary alcohols.

Dissimilar Functions Manual Curation

Function 1: Alcohol dehydrogenase.

Function 2: Bind to plasminogen, fibronectin and vitronectin. Condition: localised to cell surface.

Publications (PMID): 16356720

MoonDB Network Modules

Biological Processes

No results found.

Cellular Components

No results found.

Protein GO Annotations

Biological Processes

Showing 1 to 3 of 3 entries

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GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0000947	amino acid catabolic process to alcohol via Ehrlich pathway	IGI
GO:0006116	NADH oxidation	IDA
GO:0043458	ethanol biosynthetic process involved in glucose fermentation to ethanol	IMP

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Cellular Components

Showing 1 to 1 of 1 entries

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GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005737	cytoplasm	IDA

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Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

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Interactor	Also a MoonDB EMF protein
TBA1_YEAST	No

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Publications Associated

Showing 1 to 10 of 17 entries

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PMID	Article Title
320000	The primary structure of yeast alcohol dehydrogenase.
6277922	The primary structure of the Saccharomyces cerevisiae gene for alcohol dehydrogenase.
6279086	The alcohol dehydrogenase genes of the yeast, Saccharomyces cerevisiae: isolation, structure, and regulation.
6985717	Isolation of the structural gene for alcohol dehydrogenase by genetic complementation in yeast.
7737086	Gene linkage of two-dimensional polyacrylamide gel electrophoresis resolved proteins from isogene families in Saccharomyces cerevisiae by microsequencing of in-gel trypsin generated peptides.
7895733	Protein identifications for a Saccharomyces cerevisiae protein database.
8533473	A 29.425 kb segment on the left arm of yeast chromosome XV contains more than twice as many unknown as known open reading frames.
9169874	The nucleotide sequence of Saccharomyces cerevisiae chromosome XV.
12702265	The three zinc-containing alcohol dehydrogenases from baker's yeast, Saccharomyces cerevisiae.
14690591	Assigning function to yeast proteins by integration of technologies.

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OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 10 of 13 entries

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Domain Name	Domain ID	Source
ADH_C	IPR013149	InterPro
ADH_N	IPR013154	InterPro
ADH_N	PF08240	Pfam
ADH_ZINC	PS00059	PROSITE
ADH_zinc_N	PF00107	Pfam
ADH_Zn_CS	IPR002328	InterPro
DEBYA	S57383	PIR
GroES-like_sf	IPR011032	InterPro
NAD(P)-bd_dom_sf	IPR036291	InterPro
PKS_ER	IPR020843	InterPro

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