Protein: P48601

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P48601 (Uniprot) PRS4_DROME Rpt2 26S proteasome regulatory subunit 4 fly No
Uniprot: The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity).
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0019538 protein metabolic process 3174 GO:0006725 cellular aromatic compound metabolic process 3198 3.53e-09 8.83e-08
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
3174 GO:0044267 cellular protein metabolic process
3198 GO:0006139 nucleobase-containing compound metabolic process
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
3174 GO:0005634 nucleus
3198 GO:0005634 nucleus
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0006974 cellular response to DNA damage stimulus IMP
GO:0007623 circadian rhythm TAS
GO:0008063 Toll signaling pathway TAS
GO:0030433 ubiquitin-dependent ERAD pathway IBA
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IC
GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly IBA
GO:1901800 positive regulation of proteasomal protein catabolic process IEA
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0005654 nucleoplasm TAS
GO:0005829 cytosol TAS
GO:0005838 proteasome regulatory particle IDA
GO:0008540 proteasome regulatory particle, base subcomplex IDA
GO:0031595 nuclear proteasome complex IBA
GO:0031597 cytosolic proteasome complex IBA
No pairs of PrOnto dissimilar CC GO terms found.
PMID Article Title
8808288 Genomic organization and mapping of the mouse P26s4 ATPase gene: a member of the remarkably conserved AAA gene family.
10731132 The genome sequence of Drosophila melanogaster.
12537569 A Drosophila full-length cDNA resource.
12537572 Annotation of the Drosophila melanogaster euchromatic genome: a systematic review.
23622245 Proteasome regulation by ADP-ribosylation.
No results found.
Domain Name Domain ID Source
AAA+_ATPase IPR003593 InterPro
ATPase_AAA_core IPR003959 InterPro
ATPase_AAA_CS IPR003960 InterPro
26S_Psome_P45-like IPR005937 InterPro
P-loop_NTPase IPR027417 InterPro
26S_subunit_4 IPR035244 InterPro
AAA PF00004 Pfam
AAA PS00674 PROSITE
PTHR23073:SF24 PTHR23073:SF24 PANTHER
AAA SM00382 SMART
SSF52540 SSF52540 SUPFAM
26Sp45 TIGR01242 TIGRFAMs