Protein: P48415

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P48415 (Uniprot) SEC16_YEAST SEC16 COPII coat assembly protein SEC16 yeast No
Uniprot: Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy.
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0006139 nucleobase-containing compound metabolic process 1004 GO:0016192 vesicle-mediated transport 1134 1.23e-52 1.21e-92
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
1004 GO:0090304 nucleic acid metabolic process
1134 GO:0048193 Golgi vesicle transport
1134 GO:0022607 cellular component assembly
1134 GO:0034613 cellular protein localization
1134 GO:0051649 establishment of localization in cell
1134 GO:0043933 macromolecular complex subunit organization
1134 GO:0015031 protein transport
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
1004 GO:0005634 nucleus
1134 GO:0005783 endoplasmic reticulum
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0015031 protein transport IEA
GO:0016236 macroautophagy IMP
GO:0048208 COPII vesicle coating IDA
GO:0070973 protein localization to endoplasmic reticulum exit site IMP
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0000139 Golgi membrane IEA
GO:0005789 endoplasmic reticulum membrane IEA
GO:0012507 ER to Golgi transport vesicle membrane IDA
GO:0070971 endoplasmic reticulum exit site IDA
No pairs of PrOnto dissimilar CC GO terms found.
Interactor Also a MoonDB EMF protein
SEC23_YEAST Yes: P15303 (MoonDB)
SEC31_YEAST No
SEC24_YEAST No
SFB2_YEAST No
PMID Article Title
2188733 Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway.
7593161 Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.
7593162 SED4 encodes a yeast endoplasmic reticulum protein that binds Sec16p and participates in vesicle formation.
9023343 Selective packaging of cargo molecules into endoplasmic reticulum-derived COPII vesicles.
9169875 The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
9325247 COPII subunit interactions in the assembly of the vesicle coat.
9880808 Identification of SEC12, SED4, truncated SEC16, and EKS1/HRD3 as multicopy suppressors of ts mutants of Sar1 GTPase.
10712514 Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae.
11694599 Autophagosome requires specific early Sec proteins for its formation and NSF/SNARE for vacuolar fusion.
12235121 Sec16p potentiates the action of COPII proteins to bud transport vesicles.
14562095 Global analysis of protein localization in budding yeast.
14562106 Global analysis of protein expression in yeast.
15665377 Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
17330950 Large-scale phosphorylation analysis of alpha-factor-arrested Saccharomyces cerevisiae.
18407956 A multidimensional chromatography technology for in-depth phosphoproteome analysis.
19779198 Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
22814378 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
ACE1_Sec16_Sec31 IPR024298 InterPro
Sec16_CCD IPR024340 InterPro
Sec16_N IPR024468 InterPro
Sec16 IPR024880 InterPro
Sec16_C PF12931 Pfam
Sec16 PF12932 Pfam
Sec16_N PF12935 Pfam
S61103 S61103 PIR
ACE1-Sec16-like cd09233 CDD