Protein: Q9H190

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
Q9H190 (Uniprot) SDCB2_HUMAN SDCBP2 Syntenin-2 human No
Uniprot: Binds phosphatidylinositol 4,5-bisphosphate (PIP2). May play a role in the organization of nuclear PIP2, cell division and cell survival (PubMed:15961997).
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0019538 protein metabolic process 56 GO:0016070 RNA metabolic process 689 5.15e-08 2.82e-13
GO:0016070 RNA metabolic process 689 GO:0036211 protein modification process 695 5.81e-04 8.44e-05
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
47 GO:0044271 cellular nitrogen compound biosynthetic process
47 GO:0051252 regulation of RNA metabolic process
47 GO:0010468 regulation of gene expression
56 GO:0044267 cellular protein metabolic process
56 GO:0060255 regulation of macromolecule metabolic process
96 GO:0016070 RNA metabolic process
96 GO:0010467 gene expression
340 GO:0016070 RNA metabolic process
340 GO:0010467 gene expression
340 GO:0060255 regulation of macromolecule metabolic process
530 GO:0016070 RNA metabolic process
530 GO:0060255 regulation of macromolecule metabolic process
689 GO:0006396 RNA processing
689 GO:0051252 regulation of RNA metabolic process
689 GO:0010468 regulation of gene expression
695 GO:0006464 cellular protein modification process
695 GO:0035556 intracellular signal transduction
695 GO:0016310 phosphorylation
695 GO:0060255 regulation of macromolecule metabolic process
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
47 GO:0005654 nucleoplasm
56 GO:0005829 cytosol
96 GO:0005654 nucleoplasm
117 GO:0005634 nucleus
322 GO:0005634 nucleus
340 GO:0005634 nucleus
530 GO:0070013 intracellular organelle lumen
530 GO:0005634 nucleus
548 GO:0070013 intracellular organelle lumen
548 GO:0005634 nucleus
689 GO:0005654 nucleoplasm
695 GO:0005829 cytosol
695 GO:0005634 nucleus
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0007399 nervous system development NAS
GO:0008283 cell proliferation IMP
GO:0035556 intracellular signal transduction NAS
GO:0046907 intracellular transport NAS
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0005730 nucleolus IDA
GO:0005737 cytoplasm IDA
GO:0005886 plasma membrane IDA
GO:0016607 nuclear speck IDA
GO:0070062 extracellular exosome IDA
GO ID 1 Component 1 GO ID 2 Component 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0005730 nucleolus GO:0005886 plasma membrane 7.70e-47 3.09e-07
GO:0005886 plasma membrane GO:0016607 nuclear speck 2.37e-16 9.27e-101
GO:0016607 nuclear speck GO:0070062 extracellular exosome 7.04e-04 3.03e-123
PMID Article Title
11102519 The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein.
11152476 The neural cell recognition molecule neurofascin interacts with syntenin-1 but not with syntenin-2, both of which reveal self-associating activity.
11780052 The DNA sequence and comparative analysis of human chromosome 20.
15489334 The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15961997 Nuclear speckles and nucleoli targeting by PIP2-PDZ domain interactions.
16959974 The consensus coding sequences of human breast and colorectal cancers.
22623796 Human papillomavirus type 8 E6 oncoprotein inhibits transcription of the PDZ protein syntenin-2.
23300061 The characterization of the nuclear dynamics of syntenin-2, a PIP2 binding PDZ protein.
No results found.
Domain Name Domain ID Source
PDZ IPR001478 InterPro
PDZ_sf IPR036034 InterPro
PDZ PF00595 Pfam
PDZ PS50106 PROSITE
PDZ SM00228 SMART
SSF50156 SSF50156 SUPFAM