Protein: Q96RG2 | MoonDB v2.0

UniprotKB AC	UniprotKB ID	Gene name	Full name	Species	Curated set
Q96RG2 (Uniprot)	PASK_HUMAN	PASK	PAS domain-containing serine/threonine-protein kinase	human	No

Protein Function

Uniprot: Serine/threonine-protein kinase involved in energy homeostasis and protein translation. Phosphorylates EEF1A1, GYS1, PDX1 and RPS6. Probably plays a role under changing environmental conditions (oxygen, glucose, nutrition), rather than under standard conditions. Acts as a sensor involved in energy homeostasis: re more..

MoonDB Dissimilar Functions

Showing 1 to 1 of 1 entries

Search:

GO ID 1	Function 1	Module ID 1	GO ID 2	Function 2	Module ID 2	Association Probability (PrOnto)	Interaction Probability (PrOnto)
GO:0043170	macromolecule metabolic process	412	GO:0042886	amide transport	663	2.11e-04	2.73e-69

Previous1Next

MoonDB Network Modules

Biological Processes

Showing 1 to 7 of 7 entries

Search:

Module ID (MoonGO)	GO ID (BP)	GO Name
178	GO:0060255	regulation of macromolecule metabolic process
178	GO:0007165	signal transduction
249	GO:0060255	regulation of macromolecule metabolic process
412	GO:0019538	protein metabolic process
412	GO:0060255	regulation of macromolecule metabolic process
663	GO:0015833	peptide transport
663	GO:0008104	protein localization

Previous1Next

Cellular Components

Showing 1 to 8 of 8 entries

Search:

Module ID (MoonGO)	GO ID (CC)	GO Name
178	GO:0005634	nucleus
249	GO:0005829	cytosol
249	GO:0005634	nucleus
249	GO:0031982	vesicle
412	GO:0005829	cytosol
412	GO:0005634	nucleus
663	GO:0005829	cytosol
663	GO:0031982	vesicle

Previous1Next

Protein GO Annotations

Biological Processes

Showing 1 to 7 of 7 entries

Search:

GO ID (BP)	GO Name	Evidence Code (GO EC)
GO:0006468	protein phosphorylation	IDA
GO:0043576	regulation of respiratory gaseous exchange	ISS
GO:0045719	negative regulation of glycogen biosynthetic process	IDA
GO:0045727	positive regulation of translation	TAS
GO:0046777	protein autophosphorylation	IDA
GO:0070092	regulation of glucagon secretion	ISS
GO:2000505	regulation of energy homeostasis	ISS

Previous1Next

Cellular Components

Showing 1 to 3 of 3 entries

Search:

GO ID (CC)	GO Name	Evidence Code (GO EC)
GO:0005634	nucleus	IDA
GO:0005737	cytoplasm	IDA
GO:0005829	cytosol	IDA

Previous1Next

Dissimilar Cellular Components (PrOnto)

No pairs of PrOnto dissimilar CC GO terms found.

All Protein Interactions

Showing 1 to 10 of 28 entries

Search:

Interactor	Also a MoonDB EMF protein
4ET_HUMAN	No
B9D2_HUMAN	No
CEP44_HUMAN	No
CREB1_HUMAN	No
EF1A1_HUMAN	No
F261_HUMAN	No
FIBA_HUMAN	No
FRDA_HUMAN	No
GYS1_HUMAN	No
HS90B_HUMAN	Yes: P08238 (MoonDB)

Previous1 2 3Next

Publications Associated

Showing 1 to 10 of 20 entries

Search:

PMID	Article Title
8590280	Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1.
9110174	Large-scale concatenation cDNA sequencing.
11459942	PAS kinase: an evolutionarily conserved PAS domain-regulated serine/threonine kinase.
12168954	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.
12377121	Structure and interactions of PAS kinase N-terminal PAS domain: model for intramolecular kinase regulation.
15489334	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
15815621	Generation and annotation of the DNA sequences of human chromosomes 2 and 4.
16275910	Control of mammalian glycogen synthase by PAS kinase.
17052199	Regulation by Per-Arnt-Sim (PAS) kinase of pancreatic duodenal homeobox-1 nuclear import in pancreatic beta-cells.
17344846	Patterns of somatic mutation in human cancer genomes.

Previous1 2Next

OMIM Diseases Associated

No results found.

Protein Domains Associated

Showing 1 to 10 of 19 entries

Search:

Domain Name	Domain ID	Source
Kinase-like_dom_sf	IPR011009	InterPro
PAS	IPR000014	InterPro
PAS	PS50112	PROSITE
PAS	SM00091	SMART
PAS	cd00130	CDD
PAS-like_dom_sf	IPR035965	InterPro
PAS_9	PF13426	Pfam
Pkinase	PF00069	Pfam
Prot_kinase_dom	IPR000719	InterPro
PROTEIN_KINASE_ATP	PS00107	PROSITE

Previous1 2Next