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A Database of Extreme Multifunctional and Moonlighting Proteins
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About
Protein: Q22289
UniprotKB AC
UniprotKB ID
Gene name
Full name
Species
Curated set
Q22289 (Uniprot)
TBX9_CAEEL
tbx-9
T-box transcription factor tbx-9
worm
No
Protein Function
Uniprot:
Involved in the control of early morphogenesis of the intestine, hypodermis and body-wall muscle. Appears to have partially redundant function to tbx-8.
MoonDB Dissimilar Functions
GO ID 1
Function 1
Module ID 1
GO ID 2
Function 2
Module ID 2
Association Probability
(PrOnto)
Interaction Probability
(PrOnto)
GO:0036211
protein modification process
2309
GO:0034641
cellular nitrogen compound metabolic process
2545
1.60e-15
1.37e-09
MoonDB Network Modules
Biological Processes
Module ID
(MoonGO)
GO ID (BP)
GO Name
2158
GO:0006355
regulation of transcription, DNA-templated
2200
GO:0006355
regulation of transcription, DNA-templated
2247
GO:0006355
regulation of transcription, DNA-templated
2307
GO:0006355
regulation of transcription, DNA-templated
2309
GO:0006464
cellular protein modification process
2309
GO:0010468
regulation of gene expression
2311
GO:0006355
regulation of transcription, DNA-templated
2372
GO:0006355
regulation of transcription, DNA-templated
2386
GO:0006355
regulation of transcription, DNA-templated
2407
GO:0006355
regulation of transcription, DNA-templated
2429
GO:0006355
regulation of transcription, DNA-templated
2472
GO:0006355
regulation of transcription, DNA-templated
2499
GO:0006355
regulation of transcription, DNA-templated
2545
GO:0044271
cellular nitrogen compound biosynthetic process
2545
GO:0051252
regulation of RNA metabolic process
2545
GO:2000112
regulation of cellular macromolecule biosynthetic process
2545
GO:0010468
regulation of gene expression
2546
GO:0034645
cellular macromolecule biosynthetic process
2546
GO:0044271
cellular nitrogen compound biosynthetic process
2546
GO:0010467
gene expression
2599
GO:0034645
cellular macromolecule biosynthetic process
2599
GO:0090304
nucleic acid metabolic process
2608
GO:0006355
regulation of transcription, DNA-templated
2619
GO:0006357
regulation of transcription from RNA polymerase II promoter
2629
GO:0006357
regulation of transcription from RNA polymerase II promoter
2638
GO:0006355
regulation of transcription, DNA-templated
2639
GO:0006355
regulation of transcription, DNA-templated
2718
GO:0048598
embryonic morphogenesis
2718
GO:0006357
regulation of transcription from RNA polymerase II promoter
Cellular Components
Module ID
(MoonGO)
GO ID (CC)
GO Name
2158
GO:0005634
nucleus
2200
GO:0005634
nucleus
2247
GO:0005634
nucleus
2307
GO:0005634
nucleus
2309
GO:0005634
nucleus
2311
GO:0005634
nucleus
2372
GO:0005634
nucleus
2386
GO:0005634
nucleus
2407
GO:0005634
nucleus
2427
GO:0005634
nucleus
2429
GO:0005634
nucleus
2472
GO:0005634
nucleus
2478
GO:0005634
nucleus
2499
GO:0005634
nucleus
2545
GO:0005634
nucleus
2546
GO:0005634
nucleus
2599
GO:0005634
nucleus
2608
GO:0005634
nucleus
2619
GO:0005634
nucleus
2629
GO:0005634
nucleus
2638
GO:0005634
nucleus
2639
GO:0005634
nucleus
2718
GO:0005634
nucleus
Protein GO Annotations
Biological Processes
GO ID (BP)
GO Name
Evidence Code
(GO EC)
GO:0006351
transcription, DNA-templated
IEA
GO:0006355
regulation of transcription, DNA-templated
NAS
GO:0006357
regulation of transcription from RNA polymerase II promoter
ISS
GO:0010172
embryonic body morphogenesis
IMP
Cellular Components
GO ID (CC)
GO Name
Evidence Code
(GO EC)
GO:0005634
nucleus
ISS
GO:0005667
transcription factor complex
ISS
Dissimilar Cellular Components (PrOnto)
No pairs of PrOnto dissimilar CC GO terms found.
All Protein Interactions
Interactor
Also a MoonDB EMF protein
MBTR1_CAEEL
No
BIR1_CAEEL
No
BLMP1_CAEEL
No
CEC1_CAEEL
No
CRTC1_CAEEL
No
EGL13_CAEEL
No
EGL27_CAEEL
No
FOZI1_CAEEL
No
G4SGI5_CAEEL
No
G5ECN8_CAEEL
No
G5ECP6_CAEEL
No
G5ED66_CAEEL
No
G5EDS1_CAEEL
No
G5EDS9_CAEEL
No
G5EDU6_CAEEL
No
G5EEM0_CAEEL
No
G5EGC9_CAEEL
No
G5EGQ2_CAEEL
No
H2KYB3_CAEEL
No
H2KYH4_CAEEL
No
H2KZH8_CAEEL
No
H2KZM4_CAEEL
No
H2L0J8_CAEEL
No
H2L0L6_CAEEL
No
HDA2_CAEEL
No
HLH26_CAEEL
No
HM01_CAEEL
No
HM02_CAEEL
No
HM09_CAEEL
No
HM14_CAEEL
No
HM31_CAEEL
No
HM37_CAEEL
No
HM40_CAEEL
No
HM43_CAEEL
No
KDM5_CAEEL
No
LI15A_CAEEL
No
LIN11_CAEEL
No
LIN39_CAEEL
No
LIN59_CAEEL
No
MAB3_CAEEL
No
MED11_CAEEL
No
MED13_CAEEL
No
MED22_CAEEL
No
MEP1_CAEEL
No
MNM2_CAEEL
No
NH111_CAEEL
No
NHR67_CAEEL
No
O01446_CAEEL
No
O01996_CAEEL
No
O17006_CAEEL
No
O17670_CAEEL
Yes:
O17670 (MoonDB)
O44462_CAEEL
No
O44719_CAEEL
No
O45075_CAEEL
No
O45233_CAEEL
No
O45550_CAEEL
No
O45905_CAEEL
No
O46016_CAEEL
No
O61907_CAEEL
No
O62116_CAEEL
No
O62144_CAEEL
No
O62259_CAEEL
No
O76580_CAEEL
No
ODD2_CAEEL
No
ODR7_CAEEL
No
P91983_CAEEL
No
PHA4_CAEEL
No
POP1_CAEEL
No
Q09646_CAEEL
No
Q18054_CAEEL
No
Q18056_CAEEL
No
Q18225_CAEEL
No
Q18241_CAEEL
No
Q18533_CAEEL
No
Q18694_CAEEL
No
Q19418_CAEEL
No
Q19820_CAEEL
No
Q19937_CAEEL
No
Q19953_CAEEL
No
Q20367_CAEEL
No
Q21177_CAEEL
No
Q21192_CAEEL
No
Q21263_CAEEL
No
Q22024_CAEEL
No
Q22459_CAEEL
No
Q22510_CAEEL
No
Q22676_CAEEL
No
Q22677_CAEEL
No
Q22835_CAEEL
No
Q5TYK5_CAEEL
No
Q65CM0_CAEEL
No
Q93616_CAEEL
No
Q94234_CAEEL
No
Q95QR2_CAEEL
No
Q9BHL4_CAEEL
No
Q9BKZ8_CAEEL
No
Q9BPP1_CAEEL
No
Q9N410_CAEEL
No
Q9N5H6_CAEEL
No
Q9NAE4_CAEEL
No
Q9TXN8_CAEEL
No
Q9TZF5_CAEEL
No
Q9U226_CAEEL
No
Q9U235_CAEEL
No
Q9U289_CAEEL
No
Q9XWF2_CAEEL
No
Q9XWR1_CAEEL
No
Q9XX95_CAEEL
No
Q9XXS2_CAEEL
No
SAEG1_CAEEL
No
SAP18_CAEEL
No
SET1_CAEEL
No
SMA3_CAEEL
No
TBX8_CAEEL
No
TRA1_CAEEL
No
UNC37_CAEEL
No
V6CLN5_CAEEL
No
VAB15_CAEEL
No
VAB7_CAEEL
No
Publications Associated
PMID
Article Title
9851916
Genome sequence of the nematode C. elegans: a platform for investigating biology.
15066124
Caenorhabditis elegans T-box genes tbx-9 and tbx-8 are required for formation of hypodermis and body-wall muscle in embryogenesis.
OMIM Diseases Associated
No results found.
Protein Domains Associated
Domain Name
Domain ID
Source
TF_T-box
IPR001699
InterPro
p53-like_TF_DNA-bd
IPR008967
InterPro
TF_T-box_CS
IPR018186
InterPro
T-box_sf
IPR036960
InterPro
T-box
PF00907
Pfam
TBOX
PR00937
PRINTS
TBOX_2
PS01264
PROSITE
TBOX_1
PS01283
PROSITE
TBOX_3
PS50252
PROSITE
PTHR11267
PTHR11267
PANTHER
S41019
S41019
PIR
TBOX
SM00425
SMART
SSF49417
SSF49417
SUPFAM
TBOX
cd00182
CDD