Protein: P32835

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P32835 (Uniprot) GSP1_YEAST GSP1 GTP-binding nuclear protein GSP1/CNR1 yeast No
Uniprot: GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Essential for cell viability. By analogy with Ras, Ran may be activated when GTP is exchanged for bound GDP by RCC1 and inactivated when GTP is hydrolyzed by Ran upon activation by RanGAP1. more..
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0008104 protein localization 1184 GO:0044260 cellular macromolecule metabolic process 1268, 1275 7.50e-19 5.37e-13
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
1184 GO:0034613 cellular protein localization
1268 GO:0016070 RNA metabolic process
1268 GO:0051656 establishment of organelle localization
1268 GO:0010467 gene expression
1268 GO:0071426 ribonucleoprotein complex export from nucleus
1275 GO:0016070 RNA metabolic process
1275 GO:0034613 cellular protein localization
1275 GO:0051649 establishment of localization in cell
1275 GO:0010467 gene expression
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
1184 GO:0005634 nucleus
1268 GO:0005634 nucleus
1275 GO:0044428 nuclear part
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0000054 ribosomal subunit export from nucleus IBA
GO:0000467 exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IMP
GO:0006606 protein import into nucleus IBA
GO:0006913 nucleocytoplasmic transport TAS
GO:0006997 nucleus organization ISS
GO:0031938 regulation of chromatin silencing at telomere IMP
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0005634 nucleus IDA
GO:0005737 cytoplasm TAS
GO ID 1 Component 1 GO ID 2 Component 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0005634 nucleus GO:0005737 cytoplasm 5.14e-51 7.30e-86
PMID Article Title
7687541 Regulation of RNA processing and transport by a nuclear guanine nucleotide release protein and members of the Ras superfamily.
7895733 Protein identifications for a Saccharomyces cerevisiae protein database.
8455603 GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.
8896453 Dis3, implicated in mitotic control, binds directly to Ran and enhances the GEF activity of RCC1.
9169871 The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
11523802 Functional analysis of the yeast Ran exchange factor Prp20p: in vivo evidence for the RanGTP gradient model.
11589573 Overexpression of Bud5p can suppress mutations in the Gsp1p guanine nucleotide exchange factor Prp20p in Saccharomyces cerevisiae.
14729571 A pre-ribosome-associated HEAT-repeat protein is required for export of both ribosomal subunits.
15665377 Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.
17203074 Cex1p is a novel cytoplasmic component of the Saccharomyces cerevisiae nuclear tRNA export machinery.
17322287 Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
Small_GTPase IPR001806 InterPro
Ran_GTPase IPR002041 InterPro
Small_GTP-bd_dom IPR005225 InterPro
P-loop_NTPase IPR027417 InterPro
Ras PF00071 Pfam
GTPRANTC4 PR00627 PRINTS
RAN PS51418 PROSITE
PTHR24071 PTHR24071 PANTHER
S35504 S35504 PIR
SSF52540 SSF52540 SUPFAM
small_GTP TIGR00231 TIGRFAMs