Protein: P15303

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P15303 (Uniprot) SEC23_YEAST SEC23 Protein transport protein SEC23 yeast No
Uniprot: Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SEC23 interacts with BET3 in order to target TRAPPI complex to COPII involved in internalisation of plasma membrane proteins like the maltose transporter. more..
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0006139 nucleobase-containing compound metabolic process 1004 GO:0016192 vesicle-mediated transport 1134 1.23e-52 1.21e-92
Module ID (MoonGO) GO ID (BP) GO Name
1004 GO:0090304 nucleic acid metabolic process
1134 GO:0048193 Golgi vesicle transport
1134 GO:0022607 cellular component assembly
1134 GO:0034613 cellular protein localization
1134 GO:0051649 establishment of localization in cell
1134 GO:0043933 macromolecular complex subunit organization
1134 GO:0015031 protein transport
Module ID (MoonGO) GO ID (CC) GO Name
1004 GO:0005634 nucleus
1134 GO:0005783 endoplasmic reticulum
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0003400 regulation of COPII vesicle coating IDA
GO:0006886 intracellular protein transport IEA
GO:0006888 ER to Golgi vesicle-mediated transport IEA
GO:0016236 macroautophagy IMP
GO:0043547 positive regulation of GTPase activity IDA
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0000139 Golgi membrane IEA
GO:0005789 endoplasmic reticulum membrane IEA
GO:0030127 COPII vesicle coat IDA
No pairs of PrOnto dissimilar CC GO terms found.
PMID Article Title
1498369 Sec23p and a novel 105-kDa protein function as a multimeric complex to promote vesicle budding and protein transport from the endoplasmic reticulum.
2188733 Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway.
2670558 Yeast Sec23p acts in the cytoplasm to promote protein transport from the endoplasmic reticulum to the Golgi complex in vivo and in vitro.
3049622 Reconstitution of protein transport from the endoplasmic reticulum to the Golgi complex in yeast: the acceptor Golgi compartment is defective in the sec23 mutant.
3293799 Reconstitution of SEC gene product-dependent intercompartmental protein transport.
6996832 Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway.
7026045 Order of events in the yeast secretory pathway.
7593161 Yeast SEC16 gene encodes a multidomain vesicle coat protein that interacts with Sec23p.
7925484 Multicopy STS1 restores both protein transport and ribosomal RNA stability in a new yeast sec23 mutant allele.
8451644 Requirement for a GTPase-activating protein in vesicle budding from the endoplasmic reticulum.
8548805 COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast.
8909535 Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro.
8930902 COPII coat subunit interactions: Sec24p and Sec23p bind to adjacent regions of Sec16p.
9023343 Selective packaging of cargo molecules into endoplasmic reticulum-derived COPII vesicles.
9169875 The nucleotide sequence of Saccharomyces cerevisiae chromosome XVI.
9325247 COPII subunit interactions in the assembly of the vesicle coat.
9427388 Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast.
9428766 COPII-cargo interactions direct protein sorting into ER-derived transport vesicles.
9568718 COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes.
9624457 Role of endoplasmic reticulum-derived vesicles in the formation of Golgi elements in sec23 and sec18 Saccharomyces Cerevisiae mutants.
9685263 Nucleation of COPII vesicular coat complex by endoplasmic reticulum to Golgi vesicle SNAREs.
10198022 Clathrin and two components of the COPII complex, Sec23p and Sec24p, could be involved in endocytosis of the Saccharomyces cerevisiae maltose transporter.
10564255 Shr3p mediates specific COPII coatomer-cargo interactions required for the packaging of amino acid permeases into ER-derived transport vesicles.
10712514 Sec24p and Iss1p function interchangeably in transport vesicle formation from the endoplasmic reticulum in Saccharomyces cerevisiae.
10720463 The use of liposomes to study COPII- and COPI-coated vesicle formation and membrane protein sorting.
11086000 Lst1p and Sec24p cooperate in sorting of the plasma membrane ATPase into COPII vesicles in Saccharomyces cerevisiae.
11389436 Dynamics of the COPII coat with GTP and stable analogues.
11535824 Structure of the Sec23p/24p and Sec13p/31p complexes of COPII.
11560939 Distinct roles for the cytoplasmic tail sequences of Emp24p and Erv25p in transport between the endoplasmic reticulum and Golgi complex.
11717432 Surface structure of the COPII-coated vesicle.
11726510 An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export.
12235121 Sec16p potentiates the action of COPII proteins to bud transport vesicles.
12239560 Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat.
12671686 Self-assembly of minimal COPII cages.
12778054 Ubp3 requires a cofactor, Bre5, to specifically de-ubiquitinate the COPII protein, Sec23.
12941276 SNARE selectivity of the COPII coat.
14627716 Reconstitution of coat protein complex II (COPII) vesicle formation from cargo-reconstituted proteoliposomes reveals the potential role of GTP hydrolysis by Sar1p in protein sorting.
16269340 Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile.
17261844 The yeast orthologue of GRASP65 forms a complex with a coiled-coil protein that contributes to ER to Golgi traffic.
17287728 TRAPPI tethers COPII vesicles by binding the coat subunit Sec23.
19779198 Global analysis of Cdk1 substrate phosphorylation sites provides insights into evolution.
22814378 N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
Znf_Sec23_Sec24 IPR006895 InterPro
Sec23/24_trunk_dom IPR006896 InterPro
Sec23/24_helical_dom IPR006900 InterPro
Gelsolin-like_dom IPR007123 InterPro
Sec23_24_beta_S IPR012990 InterPro
ADF-H/Gelsolin-like_dom_sf IPR029006 InterPro
Znf_Sec23_Sec24_sf IPR036174 InterPro
Sec23/24_helical_dom_sf IPR036175 InterPro
Gelsolin-like_dom_sf IPR036180 InterPro
vWFA_dom_sf IPR036465 InterPro
Sec23 IPR037364 InterPro
Sec23_C IPR037550 InterPro
Gelsolin PF00626 Pfam
zf-Sec23_Sec24 PF04810 Pfam
Sec23_trunk PF04811 Pfam
Sec23_helical PF04815 Pfam
Sec23_BS PF08033 Pfam
BVBY23 S05742 PIR
SSF53300 SSF53300 SUPFAM
SSF81811 SSF81811 SUPFAM
SSF82754 SSF82754 SUPFAM
SSF82919 SSF82919 SUPFAM
Sec23_C cd11287 CDD