Protein: P40054

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P40054 (Uniprot) SERA_YEAST SER3 D-3-phosphoglycerate dehydrogenase 1 yeast No
Uniprot: Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L-serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate.
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0009056 catabolic process 1255 GO:0009059 macromolecule biosynthetic process 921, 1322 3.10e-17 2.99e-04
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
894 GO:0016070 RNA metabolic process
894 GO:0010467 gene expression
921 GO:0034645 cellular macromolecule biosynthetic process
921 GO:0044271 cellular nitrogen compound biosynthetic process
921 GO:0090304 nucleic acid metabolic process
1004 GO:0090304 nucleic acid metabolic process
1014 GO:0034622 cellular macromolecular complex assembly
1014 GO:0006139 nucleobase-containing compound metabolic process
1081 GO:0044267 cellular protein metabolic process
1083 GO:0010467 gene expression
1083 GO:0006139 nucleobase-containing compound metabolic process
1244 GO:0006139 nucleobase-containing compound metabolic process
1255 GO:0044248 cellular catabolic process
1255 GO:0009057 macromolecule catabolic process
1255 GO:0055114 oxidation-reduction process
1322 GO:0034645 cellular macromolecule biosynthetic process
1322 GO:0044271 cellular nitrogen compound biosynthetic process
1322 GO:0051252 regulation of RNA metabolic process
1322 GO:0010468 regulation of gene expression
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
894 GO:0044428 nuclear part
921 GO:0005634 nucleus
982 GO:0043232 intracellular non-membrane-bounded organelle
982 GO:0005634 nucleus
1004 GO:0005634 nucleus
1014 GO:0005634 nucleus
1025 GO:0005634 nucleus
1069 GO:0043232 intracellular non-membrane-bounded organelle
1069 GO:0005634 nucleus
1083 GO:0005634 nucleus
1114 GO:0005634 nucleus
1133 GO:0005634 nucleus
1155 GO:0005634 nucleus
1167 GO:0005634 nucleus
1249 GO:0016021 integral component of membrane
1289 GO:0016021 integral component of membrane
1294 GO:0043232 intracellular non-membrane-bounded organelle
1294 GO:0031981 nuclear lumen
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0006564 L-serine biosynthetic process IEA
GO:0009070 serine family amino acid biosynthetic process IMP
GO:0055114 oxidation-reduction process IEA
No results found.
No pairs of PrOnto dissimilar CC GO terms found.
PMID Article Title
9169868 The nucleotide sequence of Saccharomyces cerevisiae chromosome V.
14562106 Global analysis of protein expression in yeast.
18407956 A multidimensional chromatography technology for in-depth phosphoproteome analysis.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
26774271 Saccharomyces cerevisiae forms D-2-hydroxyglutarate and couples its degradation to D-lactate formation via a cytosolic transhydrogenase.
No results found.
Domain Name Domain ID Source
ACT_dom IPR002912 InterPro
D-isomer_2_OHA_DH_cat_dom IPR006139 InterPro
D-isomer_DH_NAD-bd IPR006140 InterPro
PGDH_2 IPR029015 InterPro
D-isomer_DH_CS1 IPR029752 InterPro
D-isomer_DH_CS IPR029753 InterPro
NAD(P)-bd_dom_sf IPR036291 InterPro
2-Hacid_dh PF00389 Pfam
2-Hacid_dh_C PF02826 Pfam
D_2_HYDROXYACID_DH_1 PS00065 PROSITE
D_2_HYDROXYACID_DH_2 PS00670 PROSITE
D_2_HYDROXYACID_DH_3 PS00671 PROSITE
ACT PS51671 PROSITE
PTHR10996:SF165 PTHR10996:SF165 PANTHER
S50584 S50584 PIR
SSF51735 SSF51735 SUPFAM