Protein: Q06208

Uniprot: Involved in transcriptional silencing and telomere length regulation. Its role in telomere length regulation results from either a block in elongation or promoting degradation of the telomere ends. Loss of RIF1 function results in derepression of an HMR silencer, whose ARS consensus element has been deleted, and in the elongation of telomeres. RAP1 may target the binding of RIF1 to silencers and telomeres. more..
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0044260 cellular macromolecule metabolic process 1063, 1123 GO:0033036 macromolecule localization 1156 1.18e-20 4.59e-11
GO:0009059 macromolecule biosynthetic process 1121, 1144 GO:0033036 macromolecule localization 1156 3.71e-18 5.96e-60
Module ID (MoonGO) GO ID (BP) GO Name
921 GO:0034645 cellular macromolecule biosynthetic process
921 GO:0044271 cellular nitrogen compound biosynthetic process
921 GO:0090304 nucleic acid metabolic process
962 GO:0006139 nucleobase-containing compound metabolic process
979 GO:0006139 nucleobase-containing compound metabolic process
1019 GO:0034314 Arp2/3 complex-mediated actin nucleation
1059 GO:0090304 nucleic acid metabolic process
1063 GO:0016070 RNA metabolic process
1063 GO:0034645 cellular macromolecule biosynthetic process
1063 GO:0010467 gene expression
1063 GO:0034654 nucleobase-containing compound biosynthetic process
1121 GO:0034645 cellular macromolecule biosynthetic process
1121 GO:0044271 cellular nitrogen compound biosynthetic process
1121 GO:0010467 gene expression
1121 GO:0090304 nucleic acid metabolic process
1123 GO:0016070 RNA metabolic process
1123 GO:0010467 gene expression
1144 GO:0034645 cellular macromolecule biosynthetic process
1144 GO:0034654 nucleobase-containing compound biosynthetic process
1156 GO:0070727 cellular macromolecule localization
1191 GO:0090304 nucleic acid metabolic process
1258 GO:0034645 cellular macromolecule biosynthetic process
1285 GO:0034645 cellular macromolecule biosynthetic process
1361 GO:0090304 nucleic acid metabolic process
Module ID (MoonGO) GO ID (CC) GO Name
921 GO:0005634 nucleus
960 GO:0005634 nucleus
982 GO:0043232 intracellular non-membrane-bounded organelle
982 GO:0005634 nucleus
986 GO:0016021 integral component of membrane
1019 GO:0030479 actin cortical patch
1059 GO:0005634 nucleus
1063 GO:0070013 intracellular organelle lumen
1063 GO:0005634 nucleus
1121 GO:0005634 nucleus
1123 GO:0031981 nuclear lumen
1144 GO:0005634 nucleus
1191 GO:0043232 intracellular non-membrane-bounded organelle
1191 GO:0005634 nucleus
1203 GO:0005634 nucleus
1272 GO:0005634 nucleus
1285 GO:0005634 nucleus
1361 GO:0044427 chromosomal part
1361 GO:0031981 nuclear lumen
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0007004 telomere maintenance via telomerase IMP
GO:0016233 telomere capping IMP
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0000784 nuclear chromosome, telomeric region IDA
GO:0070187 shelterin complex IPI
No pairs of PrOnto dissimilar CC GO terms found.
PMID Article Title
9087429 A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.
9169871 The nucleotide sequence of Saccharomyces cerevisiae chromosome XII.
14562106 Global analysis of protein expression in yeast.
17322287 Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
S55975 S55975 PIR