Protein: P06243

UniprotKB AC UniprotKB ID Gene name Full name Species Curated set
P06243 (Uniprot) CDC7_YEAST CDC7 Cell division control protein 7 yeast No
Uniprot: Serine/threonine-protein kinase. Needed for the initiation of DNA synthesis during mitosis as well as for synaptonemal complex formation and commitment to recombination during meiosis. Required for HTA1-HTB1 locus transcription repression.
MoonDB Dissimilar Functions
GO ID 1 Function 1 Module ID 1 GO ID 2 Function 2 Module ID 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0009059 macromolecule biosynthetic process 1139 GO:0009056 catabolic process 1141 3.10e-17 2.99e-04
Biological Processes
Module ID (MoonGO) GO ID (BP) GO Name
1139 GO:0034645 cellular macromolecule biosynthetic process
1139 GO:0044271 cellular nitrogen compound biosynthetic process
1139 GO:0044267 cellular protein metabolic process
1141 GO:0044248 cellular catabolic process
1141 GO:1903047 mitotic cell cycle process
1141 GO:0090304 nucleic acid metabolic process
1141 GO:2000112 regulation of cellular macromolecule biosynthetic process
1141 GO:0010468 regulation of gene expression
1141 GO:0019219 regulation of nucleobase-containing compound metabolic process
Cellular Components
Module ID (MoonGO) GO ID (CC) GO Name
1139 GO:0005634 nucleus
1141 GO:0044427 chromosomal part
1141 GO:0005634 nucleus
GO ID (BP) GO Name Evidence Code (GO EC)
GO:0000727 double-strand break repair via break-induced replication IMP
GO:0001100 negative regulation of exit from mitosis IPI
GO:0006270 DNA replication initiation IMP
GO:0006279 premeiotic DNA replication IMP
GO:0006468 protein phosphorylation IDA
GO:0006909 phagocytosis IBA
GO:0008360 regulation of cell shape IBA
GO:0010673 positive regulation of transcription from RNA polymerase II promoter involved in meiotic cell cycle IMP
GO:0018105 peptidyl-serine phosphorylation IDA
GO:0018107 peptidyl-threonine phosphorylation IMP
GO:0031334 positive regulation of protein complex assembly IDA
GO:0031938 regulation of chromatin silencing at telomere IMP
GO:0033314 mitotic DNA replication checkpoint IGI
GO:0034629 cellular protein complex localization IMP
GO:0046777 protein autophosphorylation IMP
GO:0051301 cell division IEA
GO:0060903 positive regulation of meiosis I IGI
GO:1902977 mitotic DNA replication preinitiation complex assembly IDA
GO:1904968 positive regulation of attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation IMP
GO:1905263 positive regulation of meiotic DNA double-strand break formation involved in reciprocal meiotic recombination IGI
GO ID (CC) GO Name Evidence Code (GO EC)
GO:0000775 chromosome, centromeric region IDA
GO:0000785 chromatin IDA
GO:0005634 nucleus IDA
GO:0005737 cytoplasm IBA
GO:0031431 Dbf4-dependent protein kinase complex IPI
GO ID 1 Component 1 GO ID 2 Component 2 Association Probability (PrOnto) Interaction Probability (PrOnto)
GO:0000775 chromosome, centromeric region GO:0005737 cytoplasm 2.93e-06 2.51e-08
GO:0000785 chromatin GO:0005737 cytoplasm 4.24e-25 3.35e-30
GO:0005634 nucleus GO:0005737 cytoplasm 5.14e-51 7.30e-86
PMID Article Title
1865880 CDC7 protein kinase activity is required for mitosis and meiosis in Saccharomyces cerevisiae.
2668893 Transcriptional analysis of the CDC7 protein kinase gene of Saccharomyces cerevisiae.
2850010 Characterisation of the CDC7 gene product of Saccharomyces cerevisiae as a protein kinase needed for the initiation of mitotic DNA synthesis.
3537706 Molecular characterization of cell cycle gene CDC7 from Saccharomyces cerevisiae.
9169867 The nucleotide sequence of Saccharomyces cerevisiae chromosome IV.
14562106 Global analysis of protein expression in yeast.
18407956 A multidimensional chromatography technology for in-depth phosphoproteome analysis.
24374639 The reference genome sequence of Saccharomyces cerevisiae: Then and now.
No results found.
Domain Name Domain ID Source
A25228 A25228 PIR
Prot_kinase_dom IPR000719 InterPro
Ser/Thr_kinase_AS IPR008271 InterPro
Kinase-like_dom_sf IPR011009 InterPro
Pkinase PF00069 Pfam
PROTEIN_KINASE_ST PS00108 PROSITE
PROTEIN_KINASE_DOM PS50011 PROSITE
S_TKc SM00220 SMART
SSF56112 SSF56112 SUPFAM